1-20 of 21
Stephen Safe
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

The Histone Methyltransferase Gene G9A Is Regulated by Nuclear Receptor 4A1 in Alveolar Rhabdomyosarcoma Cells

Rupesh Shrestha, Kumaravel Mohankumar, Un-ho Jin, Gregory Martin, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (3): 612–622.
https://doi.org/10.1158/1535-7163.MCT-20-0474
Published: 02 March 2021
View article titled, The Histone Methyltransferase Gene G9A Is Regulated by Nuclear Receptor 4A1 in Alveolar Rhabdomyosarcoma Cells
Open the PDF for The Histone Methyltransferase Gene G9A Is Regulated by Nuclear Receptor 4A1 in Alveolar Rhabdomyosarcoma Cells in another window
Includes: Supplementary data
Journal Articles

Interleukin-24 (IL24) Is Suppressed by PAX3-FOXO1 and Is a Novel Therapy for Rhabdomyosarcoma

Alexandra Lacey, Erik Hedrick, Yating Cheng, Kumaravel Mohankumar, Melanie Warren, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (12): 2756–2766.
https://doi.org/10.1158/1535-7163.MCT-18-0118
Published: 03 December 2018
View article titled, Interleukin-24 (IL24) Is Suppressed by PAX3-FOXO1 and Is a Novel Therapy for Rhabdomyosarcoma
Open the PDF for Interleukin-24 (IL24) Is Suppressed by PAX3-FOXO1 and Is a Novel Therapy for Rhabdomyosarcoma in another window
Includes: Supplementary data
Journal Articles

Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors

Erik Hedrick, Xi Li, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (1): 205–216.
https://doi.org/10.1158/1535-7163.MCT-16-0451
Published: 05 January 2017
View article titled, Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors
Open the PDF for Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors in another window
Includes: Supplementary data
Journal Articles

Histone Deacetylase Inhibitors Inhibit Rhabdomyosarcoma by Reactive Oxygen Species–Dependent Targeting of Specificity Protein Transcription Factors

Erik Hedrick, Lisa Crose, Corinne M. Linardic, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (9): 2143–2153.
https://doi.org/10.1158/1535-7163.MCT-15-0148
Published: 02 September 2015
View article titled, Histone Deacetylase Inhibitors Inhibit Rhabdomyosarcoma by Reactive Oxygen Species–Dependent Targeting of Specificity Protein Transcription Factors
Open the PDF for Histone Deacetylase Inhibitors Inhibit Rhabdomyosarcoma by Reactive Oxygen Species–Dependent Targeting of Specificity Protein Transcription Factors in another window
Includes: Supplementary data
Journal Articles

MicroRNA-26b Represses Colon Cancer Cell Proliferation by Inhibiting Lymphoid Enhancer Factor 1 Expression

Zichao Zhang, KyoungHyun Kim, Xiao Li, Myriam Moreno, Thad Sharp, Michael J. Goodheart, Stephen Safe, Adam J. Dupuy, Brad A. Amendt
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (7): 1942–1951.
https://doi.org/10.1158/1535-7163.MCT-13-1000
Published: 06 July 2014
View article titled, <em>MicroRNA-26b</em> Represses Colon Cancer Cell Proliferation by Inhibiting Lymphoid Enhancer Factor 1 Expression
Open the PDF for <em>MicroRNA-26b</em> Represses Colon Cancer Cell Proliferation by Inhibiting Lymphoid Enhancer Factor 1 Expression in another window
Journal Articles

The Cannabinoid WIN 55,212-2 Decreases Specificity Protein Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells

Sandeep Sreevalsan, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11): 2483–2493.
https://doi.org/10.1158/1535-7163.MCT-13-0486
Published: 06 November 2013
View article titled, The Cannabinoid WIN 55,212-2 Decreases Specificity Protein Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells
Open the PDF for The Cannabinoid WIN 55,212-2 Decreases Specificity Protein Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-Induced Targeting of MicroRNA-17-92/106b-25 Clusters

KyoungHyun Kim, Gayathri Chadalapaka, Satya S. Pathi, Un-Ho Jin, Ju-Seog Lee, Yun-Yong Park, Sung-Gook Cho, Sudhakar Chintharlapalli, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (9): 1852–1862.
https://doi.org/10.1158/1535-7163.MCT-12-0181
Published: 06 September 2012
View article titled, Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-Induced Targeting of MicroRNA-17-92/106b-25 Clusters
Open the PDF for Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-Induced Targeting of MicroRNA-17-92/106b-25 Clusters in another window
Includes: Supplementary data
Journal Articles

Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer

Xinyi Liu, Indira Jutooru, Ping Lei, KyoungHyun Kim, Syng-ook Lee, Lisa K. Brents, Paul L. Prather, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (7): 1421–1431.
https://doi.org/10.1158/1535-7163.MCT-12-0026
Published: 05 July 2012
View article titled, Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer
Open the PDF for Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells

Shu Zhang, KyoungHyun Kim, Un Ho Jin, Catherine Pfent, Huojun Cao, Brad Amendt, Xinyi Liu, Heather Wilson-Robles, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (1): 108–118.
https://doi.org/10.1158/1535-7163.MCT-11-0548
Published: 09 January 2012
View article titled, Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells
Open the PDF for Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Inhalation Delivery of a Novel Diindolylmethane Derivative for the Treatment of Lung Cancer

Nkechi Ichite, Mahavir Chougule, Apurva R. Patel, Tanise Jackson, Stephen Safe, Mandip Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (11): 3003–3014.
https://doi.org/10.1158/1535-7163.MCT-09-1104
Published: 09 November 2010
View article titled, Inhalation Delivery of a Novel Diindolylmethane Derivative for the Treatment of Lung Cancer
Open the PDF for Inhalation Delivery of a Novel Diindolylmethane Derivative for the Treatment of Lung Cancer in another window
Journal Articles

The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression

Xinyi Liu, Maen Abdelrahim, Ala Abudayyeh, Ping Lei, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (5): 1207–1217.
https://doi.org/10.1158/1535-7163.MCT-08-1097
Published: 13 May 2009
View article titled, The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression
Open the PDF for The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression in another window
Includes: Supplementary data
Journal Articles

Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression

Santhi Konduri, Jimmie Colon, Cheryl H. Baker, Stephen Safe, James L. Abbruzzese, Ala Abudayyeh, Md. Riyaz Basha, Maen Abdelrahim
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (3): 533–542.
https://doi.org/10.1158/1535-7163.MCT-08-0405
Published: 13 March 2009
View article titled, Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression
Open the PDF for Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression in another window
Includes: Supplementary data
Journal Articles

ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells

Seong-Ho Lee, Jae Hoon Bahn, Chang Kyoung Choi, Nichelle C. Whitlock, Anthony E. English, Stephen Safe, Seung Joon Baek
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (12): 3739–3750.
https://doi.org/10.1158/1535-7163.MCT-08-0548
Published: 15 December 2008
View article titled, ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells
Open the PDF for ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells in another window
Journal Articles

1,1-Bis(3′-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth

Teruo Inamoto, Sabitha Papineni, Sudhakar Chintharlapalli, Sung-Dae Cho, Stephen Safe, Ashish M. Kamat
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (12): 3825–3833.
https://doi.org/10.1158/1535-7163.MCT-08-0730
Published: 15 December 2008
View article titled, 1,1-Bis(3′-indolyl)-1-(<em>p</em>-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth
Open the PDF for 1,1-Bis(3′-indolyl)-1-(<em>p</em>-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth in another window
Includes: Supplementary data
Journal Articles

Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3′-indoly)-1-(p-substituted phenyl)methanes

Ping Lei, Maen Abdelrahim, Sung Dae Cho, Xingi Liu, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (10): 3363–3372.
https://doi.org/10.1158/1535-7163.MCT-08-0439
Published: 13 October 2008
View article titled, Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3′-indoly)-1-(p-substituted phenyl)methanes
Open the PDF for Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3′-indoly)-1-(p-substituted phenyl)methanes in another window
Journal Articles

5,5′-Dibromo-bis(3′-indolyl)methane induces Krüppel-like factor 4 and p21 in colon cancer cells

Sung Dae Cho, Sudhakar Chintharlapalli, Maen Abdelrahim, Sabitha Papineni, Shengxi Liu, Jingjing Guo, Ping Lei, Ala Abudayyeh, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (7): 2109–2120.
https://doi.org/10.1158/1535-7163.MCT-07-2311
Published: 21 July 2008
View article titled, 5,5′-Dibromo-bis(3′-indolyl)methane induces Krüppel-like factor 4 and p21 in colon cancer cells
Open the PDF for 5,5′-Dibromo-bis(3′-indolyl)methane induces Krüppel-like factor 4 and p21 in colon cancer cells in another window
Journal Articles

Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator–activated receptor γ agonists in colon cancer cells

Sudhakar Chintharlapalli, Sabitha Papineni, Indira Jutooru, Alan McAlees, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (5): 1588–1598.
https://doi.org/10.1158/1535-7163.MCT-07-0022
Published: 18 May 2007
View article titled, Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator–activated receptor γ agonists in colon cancer cells
Open the PDF for Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator–activated receptor γ agonists in colon cancer cells in another window
Journal Articles

1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator–activated receptor–dependent and independent pathways

Ping Lei, Maen Abdelrahim, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (9): 2324–2336.
https://doi.org/10.1158/1535-7163.MCT-06-0184
Published: 19 September 2006
View article titled, 1,1-Bis(3′-indolyl)-1-(<em>p</em>-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator–activated receptor–dependent and independent pathways
Open the PDF for 1,1-Bis(3′-indolyl)-1-(<em>p</em>-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator–activated receptor–dependent and independent pathways in another window
Journal Articles

1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARγ-dependent and PPARγ-independent pathways

Sudhakar Chintharlapalli, Sabitha Papineni, Stephen Safe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (5): 1362–1370.
https://doi.org/10.1158/1535-7163.MCT-06-0002
Published: 26 May 2006
View article titled, 1,1-Bis(3′-indolyl)-1-(<em>p</em>-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARγ-dependent and PPARγ-independent pathways
Open the PDF for 1,1-Bis(3′-indolyl)-1-(<em>p</em>-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARγ-dependent and PPARγ-independent pathways in another window
Journal Articles

Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure

Ismael Samudio, Marina Konopleva, Stephen Safe, Teresa McQueen, Michael Andreeff
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (12): 1982–1992.
https://doi.org/10.1158/1535-7163.MCT-05-0247
Published: 22 December 2005
View article titled, Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure
Open the PDF for Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure in another window