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Siân Jones
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Journal Articles

Abstract A027: Analytic validation of a pan-cancer tumor mutational burden assay

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Monica Nesselbush, Sian Jones, Laurel Keefer, Naomi Sengamalay, Victor Velculescu, Luis Diaz, Mark Sausen, Samuel Angiuoli
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): A027.
https://doi.org/10.1158/1535-7163.TARG-17-A027
Published: 01 January 2018
View article titled, Abstract A027: Analytic validation of a pan-cancer tumor mutational burden assay
Journal Articles

Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors

Free
Christopher A. Hamm, Diarmuid Moran, Kakuturu Rao, Patricia B. Trusk, Karen Pry, Mark Sausen, Siân Jones, Victor E. Velculescu, Massimo Cristofanilli, Sarah Bacus
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (7): 1746–1756.
https://doi.org/10.1158/1535-7163.MCT-15-0353
Published: 05 July 2016
View article titled, Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors
Open the PDF for Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors in another window
Includes: Supplementary data
Journal Articles

Therapeutic Potential of the Poly(ADP-ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer

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Maike Ihnen, Christine zu Eulenburg, Teodora Kolarova, Jing Wei Qi, Kanthinh Manivong, Meenal Chalukya, Judy Dering, Lee Anderson, Charles Ginther, Alexandra Meuter, Boris Winterhoff, Siân Jones, Victor E. Velculescu, Natarajan Venkatesan, Hong-Mei Rong, Sugandha Dandekar, Nitin Udar, Fritz Jänicke, Gerrit Los, Dennis J. Slamon, Gottfried E. Konecny
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (6): 1002–1015.
https://doi.org/10.1158/1535-7163.MCT-12-0813
Published: 09 June 2013
View article titled, Therapeutic Potential of the Poly(ADP-ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer
Open the PDF for Therapeutic Potential of the Poly(ADP-ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

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Maria C. Villarroel, N.V. Rajeshkumar, Ignacio Garrido-Laguna, Ana De Jesus-Acosta, Siân Jones, Anirban Maitra, Ralph H. Hruban, James R. Eshleman, Alison Klein, Daniel Laheru, Ross Donehower, Manuel Hidalgo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (1): 3–8.
https://doi.org/10.1158/1535-7163.MCT-10-0893
Published: 10 January 2011
View article titled, Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer
Open the PDF for Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer in another window