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Shivendra V. Singh
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Journal Articles

A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer–Induced Osteolytic Bone Resorption

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Subrata K. Pore, Eun-Ryeong Hahm, Su-Hyeong Kim, Krishna B. Singh, Lea Nyiranshuti, Joseph D. Latoche, Carolyn J. Anderson, Juraj Adamik, Deborah L. Galson, Kurt R. Weiss, Rebecca J. Watters, Boeun Lee, Prashant N. Kumta, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (2): 420–431.
https://doi.org/10.1158/1535-7163.MCT-19-0611
Published: 06 February 2020
View articletitled, A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer–Induced Osteolytic Bone Resorption
Open the PDF for A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer–Induced Osteolytic Bone Resorption in another window
Includes: Supplementary data
Journal Articles

Leelamine Is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells In Vitro and In Vivo

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Krishna B. Singh, Eun-Ryeong Hahm, Subrata K. Pore, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (10): 1800–1810.
https://doi.org/10.1158/1535-7163.MCT-19-0046
Published: 01 October 2019
View articletitled, Leelamine Is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells In Vitro and In Vivo
Open the PDF for Leelamine Is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells In Vitro and In Vivo in another window
Includes: Supplementary data
Journal Articles

Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer

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Krishna B. Singh, Xinhua Ji, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (10): 2079–2090.
https://doi.org/10.1158/1535-7163.MCT-18-0117
Published: 01 October 2018
View articletitled, Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer
Open the PDF for Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

d,l-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells

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Su-Hyeong Kim, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (7): 1946–1954.
https://doi.org/10.1158/1535-7163.MCT-09-0104
Published: 14 July 2009
View articletitled, d,l-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells
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Journal Articles

z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo

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Dong Xiao, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (1): 171–180.
https://doi.org/10.1158/1535-7163.MCT-07-0491
Published: 17 January 2008
View articletitled, z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo
Open the PDF for z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo in another window
Journal Articles

Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity

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Eun-Ryeong Hahm, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (10): 2686–2695.
https://doi.org/10.1158/1535-7163.MCT-07-0217
Published: 15 October 2007
View articletitled, Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity
Open the PDF for Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity in another window
Journal Articles

Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak

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Young-Ae Kim, Dong Xiao, Hui Xiao, Anna A. Powolny, Karen L. Lew, Megan L. Reilly, Yan Zeng, Zhou Wang, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (5): 1599–1609.
https://doi.org/10.1158/1535-7163.MCT-06-0754
Published: 18 May 2007
View articletitled, Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak
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Journal Articles

Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line

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Anna Herman-Antosiewicz, Hui Xiao, Karen L. Lew, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (5): 1673–1681.
https://doi.org/10.1158/1535-7163.MCT-06-0807
Published: 18 May 2007
View articletitled, Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line
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Journal Articles

Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1–dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic

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Anna Herman-Antosiewicz, Silvia D. Stan, Eun-Ryeong Hahm, Dong Xiao, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (4): 1249–1261.
https://doi.org/10.1158/1535-7163.MCT-06-0477
Published: 12 April 2007
View articletitled, Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1–dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic
Open the PDF for Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1–dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic in another window
Journal Articles

Benzyl isothiocyanate–induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak

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Dong Xiao, Victor Vogel, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (11): 2931–2945.
https://doi.org/10.1158/1535-7163.MCT-06-0396
Published: 22 November 2006
View articletitled, Benzyl isothiocyanate–induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak
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Journal Articles

Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak

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Shivendra V. Singh, Yan Zeng, Dong Xiao, Victor G. Vogel, Joel B. Nelson, Rajiv Dhir, Yamini B. Tripathi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (11): 1747–1754.
https://doi.org/10.1158/1535-7163.MCT-05-0223
Published: 07 November 2005
View articletitled, Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak
Open the PDF for Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak in another window
Journal Articles

Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells

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Dong Xiao, Candace S. Johnson, Donald L. Trump, Shivendra V. Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (5): 567–576.
https://doi.org/10.1158/1535-7163.567.3.5
Published: 01 May 2004
View articletitled, Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells
Open the PDF for Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells in another window
Journal Articles

JS-K, a Glutathione/Glutathione S-Transferase-activated Nitric Oxide Donor of the Diazeniumdiolate Class with Potent Antineoplastic Activity

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Paul J. Shami, Joseph E. Saavedra, Lai Y. Wang, Challice L. Bonifant, Bhalchandra A. Diwan, Shivendra V. Singh, Yijun Gu, Stephen D. Fox, Gregory S. Buzard, Michael L. Citro, David J. Waterhouse, Keith M. Davies, Xinhua Ji, Larry K. Keefer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (4): 409–417.
Published: 01 April 2003
View articletitled, JS-K, a Glutathione/Glutathione S-Transferase-activated Nitric Oxide Donor of the Diazeniumdiolate Class with Potent Antineoplastic Activity
Open the PDF for JS-K, a Glutathione/Glutathione S-Transferase-activated Nitric Oxide Donor of the Diazeniumdiolate Class with Potent Antineoplastic Activity in another window