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Sharad Sharma
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Journal Articles

Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer

Juniper A. Scribner, Jennifer G. Brown, Thomas Son, Michael Chiechi, Pam Li, Sharad Sharma, Hua Li, Anushka De Costa, Ying Li, Yan Chen, Ann Easton, Nicholas C. Yee-Toy, Francine Z. Chen, Sergey Gorlatov, Bhaswati Barat, Ling Huang, Christina R. Wolff, Jeff Hooley, Tim E. Hotaling, Timur Gaynutdinov, Valentina Ciccarone, James Tamura, Scott Koenig, Paul A. Moore, Ezio Bonvini, Deryk Loo
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2020) 19 (11): 2235–2244.
https://doi.org/10.1158/1535-7163.MCT-20-0116
Published: 03 November 2020
View article titled, Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer
Open the PDF for Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Synergistic Activities of MET/RON Inhibitor BMS-777607 and mTOR Inhibitor AZD8055 to Polyploid Cells Derived from Pancreatic Cancer and Cancer Stem Cells

Jun-Ying Zeng, Sharad Sharma, Yong-Qing Zhou, Hang-Ping Yao, Xing Hu, Ruiwen Zhang, Ming-Hai Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (1): 37–48.
https://doi.org/10.1158/1535-7163.MCT-13-0242
Published: 13 January 2014
View article titled, Synergistic Activities of MET/RON Inhibitor BMS-777607 and mTOR Inhibitor AZD8055 to Polyploid Cells Derived from Pancreatic Cancer and Cancer Stem Cells
Open the PDF for Synergistic Activities of MET/RON Inhibitor BMS-777607 and mTOR Inhibitor AZD8055 to Polyploid Cells Derived from Pancreatic Cancer and Cancer Stem Cells in another window
Includes: Supplementary data
Journal Articles

Small-Molecule Inhibitor BMS-777607 Induces Breast Cancer Cell Polyploidy with Increased Resistance to Cytotoxic Chemotherapy Agents

Sharad Sharma, Jun-Ying Zeng, Chun-Mei Zhuang, Yong-Qing Zhou, Hang-Ping Yao, Xing Hu, Ruiwen Zhang, Ming-Hai Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5): 725–736.
https://doi.org/10.1158/1535-7163.MCT-12-1079
Published: 08 May 2013
View article titled, Small-Molecule Inhibitor BMS-777607 Induces Breast Cancer Cell Polyploidy with Increased Resistance to Cytotoxic Chemotherapy Agents
Open the PDF for Small-Molecule Inhibitor BMS-777607 Induces Breast Cancer Cell Polyploidy with Increased Resistance to Cytotoxic Chemotherapy Agents in another window
Includes: Supplementary data