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Sayaka Tsukioka
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Journal Articles

Abstract P020: Schlafen 11 (SLFN11) as a predictive biomarker of the response to TAS1553, a novel small molecule ribonucleotide reductase subunit interaction inhibitor

Hiroto Fukushima, Hiroyuki Ueno, Takuya Hoshino, Wakako Yano, Hiraku Itadani, Miki Terasaka, Sayaka Tsukioka, Takamasa Suzuki, Shoki Hara, Yoshio Ogino, Khoon Tee Chong, Tatsuya Suzuki, Yoshihiro Otsu, Satoshi Ito, Nozomu Tanaka, Seiji Miyahara
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12_Supplement): P020.
https://doi.org/10.1158/1535-7163.TARG-21-P020
Published: 01 December 2021
View article titled, Abstract P020: Schlafen 11 (SLFN11) as a predictive biomarker of the response to TAS1553, a novel small molecule ribonucleotide reductase subunit interaction inhibitor
Journal Articles

Abstract A063: TAS1553, a novel class of RNR inhibitor, demonstrates synergistic antitumor efficacy in combination with nucleoside analogues

Takuya Hoshino, Hiroyuki Ueno, Wakako Yano, Sayaka Tsukioka, Seiji Miyahara, Takamasa Suzuki, Kazutaka Miyadera, Teruhiro Utsugi, Takeshi Sagara
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): A063.
https://doi.org/10.1158/1535-7163.TARG-19-A063
Published: 01 December 2019
View article titled, Abstract A063: TAS1553, a novel class of RNR inhibitor, demonstrates synergistic antitumor efficacy in combination with nucleoside analogues
Journal Articles

Abstract B88: TAS-114, a dUTPase inhibitor, in combination with pemetrexed is a novel strategy for the treatment of NSCLC.

Wakako Yano, Sayaka Tsukioka, Tatsushi Yokogawa, Satoko Ito, Keiji Ishida, Keisuke Yamamura, Akio Fujioka, Masayoshi Fukuoka, Kenichi Matsuo, Kazuharu Noguchi, Teruhiro Utsugi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): B88.
https://doi.org/10.1158/1535-7163.TARG-13-B88
Published: 01 November 2013
View article titled, Abstract B88: TAS-114, a dUTPase inhibitor, in combination with pemetrexed is a novel strategy for the treatment of NSCLC.
Journal Articles

Abstract B89: Expression of DNA damage repair enzymes determine the efficacy of a novel dUTPase inhibitor, TAS-114.

Sayaka Tsukioka, Wakako Yano, Tatsushi Yokogawa, Takeshi Wakasa, Akio Fujioka, Keisuke Yamamura, Satoko Itoh, Masayoshi Fukuoka, Kenichi Matsuo, Kazuharu Noguchi, Teruhiro Utsugi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): B89.
https://doi.org/10.1158/1535-7163.TARG-13-B89
Published: 01 November 2013
View article titled, Abstract B89: Expression of DNA damage repair enzymes determine the efficacy of a novel dUTPase inhibitor, TAS-114.
Journal Articles

Abstract B87: Preclinical investigation of the potentiation in antitumor effect of TAS-102, a novel oral anti-neoplastic nucleoside agent, in combination with irinotecan (CPT-11) in colorectal cancer.

Keiji Ishida, Nozomu Tanaka, Sayaka Tsukioka, Kokoro Eshima, Akio Fujioka, Keisuke Yamamura, Satoko Ito, Kenichi Matsuo, Teruhiro Utsugi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): B87.
https://doi.org/10.1158/1535-7163.TARG-13-B87
Published: 01 November 2013
View article titled, Abstract B87: Preclinical investigation of the potentiation in antitumor effect of TAS-102, a novel oral anti-neoplastic nucleoside agent, in combination with irinotecan (CPT-11) in colorectal cancer.
Journal Articles

Synergistic Antitumor Effect of S-1 and HER2-Targeting Agents in Gastric Cancer with HER2 Amplification

Junko Tanizaki, Isamu Okamoto, Ken Takezawa, Sayaka Tsukioka, Junji Uchida, Mamoru Kiniwa, Masahiro Fukuoka, Kazuhiko Nakagawa
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (5): 1198–1207.
https://doi.org/10.1158/1535-7163.MCT-10-0045
Published: 09 May 2010
View article titled, Synergistic Antitumor Effect of S-1 and HER2-Targeting Agents in Gastric Cancer with <em>HER2</em> Amplification
Open the PDF for Synergistic Antitumor Effect of S-1 and HER2-Targeting Agents in Gastric Cancer with <em>HER2</em> Amplification in another window
Journal Articles

Synergistic antitumor effect of S-1 and the epidermal growth factor receptor inhibitor gefitinib in non-small cell lung cancer cell lines: role of gefitinib-induced down-regulation of thymidylate synthase

Takafumi Okabe, Isamu Okamoto, Sayaka Tsukioka, Junji Uchida, Tsutomu Iwasa, Takeshi Yoshida, Erina Hatashita, Yuki Yamada, Taroh Satoh, Kenji Tamura, Masahiro Fukuoka, Kazuhiko Nakagawa
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (3): 599–606.
https://doi.org/10.1158/1535-7163.MCT-07-0567
Published: 17 March 2008
View article titled, Synergistic antitumor effect of S-1 and the epidermal growth factor receptor inhibitor gefitinib in non-small cell lung cancer cell lines: role of gefitinib-induced down-regulation of thymidylate synthase
Open the PDF for Synergistic antitumor effect of S-1 and the epidermal growth factor receptor inhibitor gefitinib in non-small cell lung cancer cell lines: role of gefitinib-induced down-regulation of thymidylate synthase in another window