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Sarina Piha-PAul
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Journal Articles

Abstract A167: Targeting HER2 (ERBB2) amplification identified by next-generation sequencing (NGS) in patients with advanced or metastatic solid tumors

Ecaterina Ileana Dumbrava, Kavitha Balaji, Kanwal Raghav, Milind Javle, Mariela Blum-Murphy, Blessy Sajan, Scott Kopetz, Russell Broaddus, Mark Routbort, Shubham Pant, Apostolia Tsimberidou, Vivek Subbiah, David S. Hong, Jordi Rodon Ahnert, Kenna Shaw, Sarina Piha-Paul, Funda Meric-Bernstam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): A167.
DOI: https://doi.org/10.1158/1535-7163.TARG-17-A167
Published: 01 January 2018
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Journal Articles

Abstract A093: Phase 1/2 study of INCB054329, a bromodomain and extraterminal (BET) protein inhibitor, in patients (pts) with advanced malignancies

Gerald Falchook, Moshe Talpaz, Monica Mita, Russ Szmulewitz, Sarina Piha-Paul, Wael Harb, Daniel Morgensztern, Jason Kaplan, Pamela Munster, Robert F. Cornell, Fred Zheng, Swamy Yeleswaram, Gongfu Zhou, Ryan Cassaday
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): A093.
DOI: https://doi.org/10.1158/1535-7163.TARG-17-A093
Published: 01 January 2018
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Journal Articles

TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics

Jennifer J. Wheler, Filip Janku, Aung Naing, Yali Li, Bettzy Stephen, Ralph Zinner, Vivek Subbiah, Siqing Fu, Daniel Karp, Gerald S. Falchook, Apostolia M. Tsimberidou, Sarina Piha-Paul, Roosevelt Anderson, Danxia Ke, Vincent Miller, Roman Yelensky, J. Jack Lee, David Hong, Razelle Kurzrock
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2016) 15 (10): 2475–2485.
DOI: https://doi.org/10.1158/1535-7163.MCT-16-0196
Published: 02 October 2016
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Includes: Supplementary data
Journal Articles

Abstract C50: Phase I dose escalation study of the oral multi-kinase VEGF inhibitor regorafenib and the anti-EGFR monoclonal antibody cetuximab in patients with advanced solid tumors including colorectal cancer

Vivek Subbiah, David S. Hong, Behrang Amini, Sarina Piha-Paul, Joanna Grace Fernandez, Siquing Fu, Apostolia M. Tsimberidou, Aung Naing, Filip Janku, Daniel D. Karp, Michael Overman, Cathy Eng, Scott Kopetz, Funda Meric-Bernstam, Gerald S. Falchook
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): C50.
DOI: https://doi.org/10.1158/1535-7163.TARG-15-C50
Published: 01 December 2015
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Journal Articles

Abstract LB-C17: A phase I study of everolimus (mTOR inhibitor) in combination with vandetanib (multikinase inhibitor of VEGFR, EGFR, and RET) in advanced solid tumors including molecularly matched aberrations

Tina Cascone, Kenneth R. Hess, Sarina Piha-Paul, David S. Hong, Michael Roxas, Ishwaria M. Subbiah, Siquing Fu, Aung Naing, Filip Janku, Daniel Karp, Steven I. Sherman, Funda Meric-Bernstam, John V. Heymach, Vivek Subbiah
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): LB-C17.
DOI: https://doi.org/10.1158/1535-7163.TARG-15-LB-C17
Published: 01 December 2015
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Journal Articles

Abstract C44: Phase I dose escalation study of temsirolimus in combination with metformin in patients with advanced cancers

Muhammad Rizwan Khawaja, Vinu Madhusudanannair, Chaan Ng, Alpa Nick, Filip Janku, Sarina Piha-Paul, Robert Coleman, Pamela Soliman, Siqing Fu, David Hong, Daniel Karp, Vivek Subbiah, Apostolia Tsimberidou, Funda Meric-Bernstam, Karen Lu, Aung Naing
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): C44.
DOI: https://doi.org/10.1158/1535-7163.TARG-15-C44
Published: 01 December 2015
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Journal Articles

Abstract A36: Circulating cell-free DNA as a marker for response and resistance to BRAF and EGFR inhibition in BRAF-mutated metastatic colorectal cancer

Van Morris, Filip Janku, Helen Huang, Siqing Fu, Michael Overman, Sarina Piha-Paul, Vivek Subbiah, Bryan Kee, Apostolia Tsimbierdou, David Fogelman, Imad Shurieqi, Shanequa Manuel, Antonio Scamardo, Richard Lanman, Nicolas Sommer, David Hong, Scott Kopetz
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A36.
DOI: https://doi.org/10.1158/1535-7163.TARG-15-A36
Published: 01 December 2015
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Journal Articles

Abstract C198: BRAF mutation testing of archival tumor samples with a novel, rapid, fully-automated molecular diagnostics prototype platform.

Helen J. Huang, Bart Claes, Gerald S. Falchook, Benoit Devogelaere, Aung Naing, Siqing Fu, Sarina Piha-Paul, David S. Hong, Veronica R. Holley, Apostolia M. Tsimberidou, Vanda M. Stepanek, Kevin B. Kim, Laura S. Angelo, Vivek Subbiah, Jennifer J. Wheler, Ralph G. Zinner, Daniel D. Karp, Rajyalakshmi Luthra, Erwin Sablon, Geert Maertens, Funda Meric-Bernstam, Razelle Kurzrock, Stefan Scherer, Filip Janku
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): C198.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-C198
Published: 01 November 2013
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Journal Articles

Abstract C69: Phase I trial of lenalidomide and valproic acid in patients with advanced cancer.

Mehmet A. Bilen, Siqing Fu, David S. Hong, Jennifer J. Wheler, Maen Abdelrahim, Gerald S. Falchook, Apostlia M. Tsimberidou, Filip Janku, Sarina Piha-Paul, Ralph Zinner, Razelle Kurzrock, Aung Naing
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): C69.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-C69
Published: 01 November 2013
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Journal Articles

Abstract A211: A phase I study of MABp1, a first-in-human, first-true human monoclonal antibody against the IL-1 in patients with advanced cancers.

David S. Hong, Aung Naing, Gerald S. Falchook, Sarina Piha-PAul, Jennifer J. Wheler, Siqing Fu, Apostolia M. Tsimberidou, David Hui, Rebecca Scott, Rabia Khan, Reena Mistry, Julia Talley, Seema Chauhan, Derrick Bermudez, Michael Stecher, John Simard, Razelle Kurzrock
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): A211.
DOI: https://doi.org/10.1158/1535-7163.TARG-11-A211
Published: 12 November 2011
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Journal Articles

Abstract B134: PIK3CA mutations in patients with advanced cancers treated in phase I clinical trials

Filip Janku, Ignacio Garrido‐Laguna, David S. Hong, Apostolia M. Tsimberidou, Aung Naing, Gerald S. Falchook, Jennifer J. Wheler, Stacy L. Moulder, Siqing Fu, Sarina Piha‐Paul, Razelle Kurzrock
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B134.
DOI: https://doi.org/10.1158/1535-7163.TARG-09-B134
Published: 10 December 2009
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