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Sarah J. Freemantle
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Journal Articles

A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers

Masanori Kawakami, Lisa Maria Mustachio, Yulong Chen, Zibo Chen, Xiuxia Liu, Cheng-Hsin Wei, Jason Roszik, Adam S. Kittai, Alexey V. Danilov, Xiaoshan Zhang, Bingliang Fang, Jing Wang, John V. Heymach, Liliya Tyutyunyk-Massey, Sarah J. Freemantle, Jonathan M. Kurie, Xi Liu, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2021) 20 (3): 477–489.
https://doi.org/10.1158/1535-7163.MCT-19-0987
Published: 02 March 2021
View article titled, A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers
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Includes: Supplementary data
Journal Articles

Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2

Alexey V. Danilov, Shanhu Hu, Bernardo Orr, Kristina Godek, Lisa Maria Mustachio, David Sekula, Xi Liu, Masanori Kawakami, Faye M. Johnson, Duane A. Compton, Sarah J. Freemantle, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (11): 2758–2766.
https://doi.org/10.1158/1535-7163.MCT-16-0127
Published: 01 November 2016
View article titled, Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2
Open the PDF for Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2 in another window
Includes: Multimedia, Supplementary data
Journal Articles

Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Patients with Lung Cancer

Tian Ma, Fabrizio Galimberti, Cherie P. Erkmen, Vincent Memoli, Fadzai Chinyengetere, Lorenzo Sempere, Jan H. Beumer, Bean N. Anyang, William Nugent, David Johnstone, Gregory J. Tsongalis, Jonathan M. Kurie, Hua Li, James DiRenzo, Yongli Guo, Sarah J. Freemantle, Konstantin H. Dragnev, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (8): 1545–1555.
https://doi.org/10.1158/1535-7163.MCT-12-0933
Published: 08 August 2013
View article titled, Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Patients with Lung Cancer
Open the PDF for Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Patients with Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Evidence for the Ubiquitin Protease UBP43 as an Antineoplastic Target

Yongli Guo, Fadzai Chinyengetere, Andrey V. Dolinko, Alexandra Lopez-Aguiar, Yun Lu, Fabrizio Galimberti, Tian Ma, Qing Feng, David Sekula, Sarah J. Freemantle, Angeline S. Andrew, Vincent Memoli, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (9): 1968–1977.
https://doi.org/10.1158/1535-7163.MCT-12-0248
Published: 06 September 2012
View article titled, Evidence for the Ubiquitin Protease UBP43 as an Antineoplastic Target
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Includes: Supplementary data
Journal Articles

UBE1L represses PML/RARα by targeting the PML domain for ISG15ylation

Sumit J. Shah, Steven Blumen, Ian Pitha-Rowe, Sutisak Kitareewan, Sarah J. Freemantle, Qing Feng, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (4): 905–914.
https://doi.org/10.1158/1535-7163.MCT-07-0515
Published: 15 April 2008
View article titled, UBE1L represses PML/RARα by targeting the PML domain for ISG15ylation
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