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Sameer H. Issaq
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Journal Articles

Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the novel NAMPT Inhibitor OT-82

Susana S. Najera, Christopher J. Ricketts, Laura S. Schmidt, Julia I. Medina, Keita Saito, Lilia Ileva, Jeffrey R. Brender, Amy M. James, Cody J. Peer, Brad Gouker, Baktiar O. Karim, Olga Chernova, Catherine Wells, Ming-Hui Wei, Youfeng Yang, Xiaohu Zhang, Carleen Klumpp-Thomas, Jameson Travers, Lu Chen, Kelli M. Wilson, Sameer H. Issaq, William D. Figg, Simone Difilippantonio, Joseph D. Kalen, Murali C. Krishna, Craig J. Thomas, Michele Ceribelli, Christine M. Heske, Daniel R. Crooks, Jordan L. Meier
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024)
https://doi.org/10.1158/1535-7163.MCT-24-0225
Published: 14 October 2024
View article titled, Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the novel NAMPT Inhibitor OT-82
Open the PDF for Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the novel NAMPT Inhibitor OT-82 in another window
Includes: Supplementary data
Journal Articles

EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth

Sameer H. Issaq, Arnulfo Mendoza, Ria Kidner, Tracy I. Rosales, Damien Y. Duveau, Christine M. Heske, Jason M. Rohde, Matthew B. Boxer, Craig J. Thomas, Ralph J. DeBerardinis, Lee J. Helman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (7): 1520–1529.
https://doi.org/10.1158/1535-7163.MCT-19-0748
Published: 02 July 2020
View article titled, EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth
Open the PDF for EWS-FLI1–regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth in another window
Includes: Supplementary data