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Said Sebti
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Journal Articles

Rb–Raf-1 Interaction Disruptor RRD-251 Induces Apoptosis in Metastatic Melanoma Cells and Synergizes with Dacarbazine

Sandeep Singh, Rebecca Davis, Vignesh Alamanda, Roberta Pireddu, Daniel Pernazza, Said Sebti, Nicholas Lawrence, Srikumar Chellappan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (12): 3330–3341.
https://doi.org/10.1158/1535-7163.MCT-10-0442
Published: 14 December 2010
View article titled, Rb–Raf-1 Interaction Disruptor RRD-251 Induces Apoptosis in Metastatic Melanoma Cells and Synergizes with Dacarbazine
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Journal Articles

Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins

Jun Wei, Shinichi Kitada, Michele F. Rega, Aras Emdadi, Hongbin Yuan, Jason Cellitti, John L. Stebbins, Dayong Zhai, Jiazhi Sun, Li Yang, Russell Dahl, Ziming Zhang, Bainan Wu, Si Wang, Tyler A. Reed, Nicholas Lawrence, Said Sebti, John C. Reed, Maurizio Pellecchia
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (4): 904–913.
https://doi.org/10.1158/1535-7163.MCT-08-1050
Published: 16 April 2009
View article titled, Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins
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Includes: Supplementary data
Journal Articles

Phase I pharmacokinetic and pharmacodynamic study of the inhibitor of activation of AKT (p-Akt), triciribine phosphate monohydrate (TCN-PM), in solid malignancies

Christopher Garrett, Domenico Coppola, Robert Wenham, Christopher Cubitt, Anthony Neuger, Timothy Frost, Daniel Sullivan, Jin Cheng, Said Sebti
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B71.
Published: 01 November 2007
View article titled, Phase I pharmacokinetic and pharmacodynamic study of the inhibitor of activation of AKT (p-Akt), triciribine phosphate monohydrate (TCN-PM), in solid malignancies
Journal Articles

Identification of inhibitors of Rb-Raf-1 binding. A new target for anticancer drug design.

Daniele Pernazza, Adam Carie, Piyali Dasgupta, Rebecca Kinkade, Said Sebti, Srikumar Chellappan, Nicholas Lawrence
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): C230.
Published: 01 November 2007
View article titled, Identification of inhibitors of Rb-Raf-1 binding. A new target for anticancer drug design.
Journal Articles

p53 α-Helix mimetics antagonize p53/MDM2 interaction and activate p53

Lihong Chen, Hang Yin, Bilal Farooqi, Said Sebti, Andrew D. Hamilton, Jiandong Chen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (6): 1019–1025.
https://doi.org/10.1158/1535-7163.MCT-04-0342
Published: 14 June 2005
View article titled, p53 α-Helix mimetics antagonize p53/MDM2 interaction and activate p53
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Journal Articles

Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity

James Turkson, Shumin Zhang, Jay Palmer, Heidi Kay, Joseph Stanko, Linda B. Mora, Said Sebti, Hua Yu, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (12): 1533–1542.
https://doi.org/10.1158/1535-7163.1533.3.12
Published: 04 January 2005
View article titled, Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity
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Journal Articles

Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity

James Turkson, Joon S. Kim, Shumin Zhang, Jing Yuan, Mei Huang, Matthew Glenn, Eric Haura, Said Sebti, Andrew D. Hamilton, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (3): 261–269.
https://doi.org/10.1158/1535-7163.261.3.3
Published: 16 March 2004
View article titled, Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity
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Journal Articles

Combination Therapy with AG-490 and Interleukin 12 Achieves Greater Antitumor Effects than Either Agent Alone

Lyudmila Burdelya, Robyn Catlett-Falcone, Alexander Levitzki, Fengdong Cheng, Linda B. Mora, Eduardo Sotomayor, Domenico Coppola, JiaZhi Sun, Said Sebti, William S. Dalton, Richard Jove, Hua Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (11): 893–899.
Published: 01 September 2002
View article titled, Combination Therapy with AG-490 and Interleukin 12 Achieves Greater Antitumor Effects than Either Agent Alone
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