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Roland E. Kontermann
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Journal Articles

Triple Targeting of HER Receptors Overcomes Heregulin-mediated Resistance to EGFR Blockade in Colorectal Cancer

Alexander Rau, Nicole Janssen, Lennart Kühl, Thomas Sell, Svetlana Kalmykova, Thomas E. Mürdter, Marc-H. Dahlke, Christine Sers, Markus Morkel, Matthias Schwab, Roland E. Kontermann, Monilola A. Olayioye
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (5): 799–809.
https://doi.org/10.1158/1535-7163.MCT-21-0818
Published: 04 May 2022
View article titled, Triple Targeting of HER Receptors Overcomes Heregulin-mediated Resistance to EGFR Blockade in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Inhibition of Tumor Cell Growth and Cancer Stem Cell Expansion by a Bispecific Antibody Targeting EGFR and HER3

Alexander Rau, Wolfgang S. Lieb, Oliver Seifert, Jonas Honer, Dennis Birnstock, Fabian Richter, Nadine Aschmoneit, Monilola A. Olayioye, Roland E. Kontermann
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (7): 1474–1485.
https://doi.org/10.1158/1535-7163.MCT-19-1095
Published: 02 July 2020
View article titled, Inhibition of Tumor Cell Growth and Cancer Stem Cell Expansion by a Bispecific Antibody Targeting EGFR and HER3
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Includes: Supplementary data
Journal Articles

IL15-Based Trifunctional Antibody-Fusion Proteins with Costimulatory TNF-Superfamily Ligands in the Single-Chain Format for Cancer Immunotherapy

Nadine Beha, Markus Harder, Sarah Ring, Roland E. Kontermann, Dafne Müller
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (7): 1278–1288.
https://doi.org/10.1158/1535-7163.MCT-18-1204
Published: 01 July 2019
View article titled, IL15-Based Trifunctional Antibody-Fusion Proteins with Costimulatory TNF-Superfamily Ligands in the Single-Chain Format for Cancer Immunotherapy
Open the PDF for IL15-Based Trifunctional Antibody-Fusion Proteins with Costimulatory TNF-Superfamily Ligands in the Single-Chain Format for Cancer Immunotherapy in another window
Includes: Supplementary data
Journal Articles

Superior Properties of Fc-comprising scTRAIL Fusion Proteins

Meike Hutt, Lisa Marquardt, Oliver Seifert, Martin Siegemund, Ines Müller, Dagmar Kulms, Klaus Pfizenmaier, Roland E. Kontermann
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (12): 2792–2802.
https://doi.org/10.1158/1535-7163.MCT-17-0551
Published: 03 December 2017
View article titled, Superior Properties of Fc-comprising scTRAIL Fusion Proteins
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Includes: Supplementary data
Journal Articles

Combining Antibody-Directed Presentation of IL-15 and 4-1BBL in a Trifunctional Fusion Protein for Cancer Immunotherapy

Vanessa Kermer, Nora Hornig, Markus Harder, Anastasiia Bondarieva, Roland E. Kontermann, Dafne Müller
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (1): 112–121.
https://doi.org/10.1158/1535-7163.MCT-13-0282
Published: 13 January 2014
View article titled, Combining Antibody-Directed Presentation of IL-15 and 4-1BBL in a Trifunctional Fusion Protein for Cancer Immunotherapy
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Includes: Supplementary data
Journal Articles

Tetravalent Antibody–scTRAIL Fusion Proteins with Improved Properties

Oliver Seifert, Aline Plappert, Sina Fellermeier, Martin Siegemund, Klaus Pfizenmaier, Roland E. Kontermann
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (1): 101–111.
https://doi.org/10.1158/1535-7163.MCT-13-0396
Published: 13 January 2014
View article titled, Tetravalent Antibody–scTRAIL Fusion Proteins with Improved Properties
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Includes: Supplementary data
Journal Articles

An Antibody Fusion Protein for Cancer Immunotherapy Mimicking IL-15 trans-Presentation at the Tumor Site

Vanessa Kermer, Volker Baum, Nora Hornig, Roland E. Kontermann, Dafne Müller
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (6): 1279–1288.
https://doi.org/10.1158/1535-7163.MCT-12-0019
Published: 10 June 2012
View article titled, An Antibody Fusion Protein for Cancer Immunotherapy Mimicking IL-15 <em>trans</em>-Presentation at the Tumor Site
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Includes: Supplementary data