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Roger J. Griffin
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Journal Articles

Chemosensitization of Cancer Cells by KU-0060648, a Dual Inhibitor of DNA-PK and PI-3K

Joanne M. Munck, Michael A. Batey, Yan Zhao, Helen Jenkins, Caroline J. Richardson, Celine Cano, Michele Tavecchio, Jody Barbeau, Julia Bardos, Liam Cornell, Roger J. Griffin, Keith Menear, Andrew Slade, Pia Thommes, Niall M.B. Martin, David R. Newell, Graeme C.M. Smith, Nicola J. Curtin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (8): 1789–1798.
https://doi.org/10.1158/1535-7163.MCT-11-0535
Published: 08 August 2012
View articletitled, Chemosensitization of Cancer Cells by KU-0060648, a Dual Inhibitor of DNA-PK and PI-3K
Open the PDF for Chemosensitization of Cancer Cells by KU-0060648, a Dual Inhibitor of DNA-PK and PI-3K in another window
Includes: Supplementary data
Journal Articles

Abstract A140: Identification of substituted isoindolinones as potent inhibitors of the MDM2‐p53 protein‐protein interaction

Anna Watson, Junfeng Liu, Elizabeth Armstrong, Timothy Blackburn, Jane A. Endicott, Bernard T. Golding, Roger J. Griffin, Xiaohong Lu, David R. Newell, Martin E.M. Noble, Christiane Riedinger, John Lunec, Ian R. Hardcastle
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): A140.
https://doi.org/10.1158/1535-7163.TARG-09-A140
Published: 10 December 2009
View articletitled, Abstract A140: Identification of substituted isoindolinones as potent inhibitors of the MDM2‐p53 protein‐protein interaction
Journal Articles

Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity

Huw D. Thomas, Kappusamy Saravanan, Lan-Zhen Wang, Mei-Ju Lin, Julian S. Northen, Hannah Barlow, Marion Barton, David R. Newell, Roger J. Griffin, Bernard T. Golding, Nicola J. Curtin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (7): 1828–1837.
https://doi.org/10.1158/1535-7163.MCT-08-1208
Published: 14 July 2009
View articletitled, Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
Open the PDF for Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity in another window
Includes: Supplementary data
Journal Articles

Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation

Marzia Pennati, Allyson J. Campbell, Maria Curto, Mara Binda, YuZhu Cheng, Lan-Zeng Wang, Nicola Curtin, Bernard T. Golding, Roger J. Griffin, Ian R. Hardcastle, Andrew Henderson, Nadia Zaffaroni, David R. Newell
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (9): 1328–1337.
https://doi.org/10.1158/1535-7163.MCT-05-0022
Published: 16 September 2005
View articletitled, Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation
Open the PDF for Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation in another window