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Robert Brown
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Journal Articles

Abstract B04: RAD51 expression as a biomarker of homologous recombination deficiency in ovarian cancer

Michal M. Hoppe, David SP Tan, Diana GZ Lim, Anthony Karnezis, David Huntsman, Jennifer Steel, Xinxue Liu, James Paul, Liz-Anne Lewsley, Nadeem Siddiqui, Robert Brown, Anand D. Jeyasekharan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (10_Supplement): B04.
https://doi.org/10.1158/1538-8514.SYNTHLETH-B04
Published: 02 October 2017
View article titled, Abstract B04: RAD51 expression as a biomarker of homologous recombination deficiency in ovarian cancer
Journal Articles

Abstract A162: Targeting chromatin: Small molecules reactivating H3K27me3 silenced genes.

Nadine Chapman-Rothe, Elham Shamsaei, Fanny Cherblanc, Thota Ganesh, James P. Snyder, Matthew J. Fuchter, Robert Brown
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): A162.
https://doi.org/10.1158/1535-7163.TARG-11-A162
Published: 12 November 2011
View article titled, Abstract A162: Targeting chromatin: Small molecules reactivating H3K27me3 silenced genes.
Journal Articles

Abstract B165: Structural and biological studies on analogues of the natural product histone methyltransferase inhibitor chaetocin.

Fanny L. Cherblanc, Ya-Pei Lo, Elaine M. Bignell, Laura Alcazar-Fuoli, Robert Brown, Nadine Chapman-Rothe, Henry S. Rzepa, Matthew J. Fuchter
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): B165.
https://doi.org/10.1158/1535-7163.TARG-11-B165
Published: 12 November 2011
View article titled, Abstract B165: Structural and biological studies on analogues of the natural product histone methyltransferase inhibitor chaetocin.
Journal Articles

Abstract PL05-04: Epigenetic marks as biomarkers and their mechanisms of maintenance as targets in ovarian cancer.

Robert Brown, Wei Dai, Nadine Chapman-Rothe, Edward Curry, Matt Fuchter
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): PL05-04.
https://doi.org/10.1158/1535-7163.TARG-11-PL05-04
Published: 12 November 2011
View article titled, Abstract PL05-04: Epigenetic marks as biomarkers and their mechanisms of maintenance as targets in ovarian cancer.
Journal Articles

Ovarian Cancer Stem Cell–Like Side Populations Are Enriched Following Chemotherapy and Overexpress EZH2

Siân Rizzo, Jenny M. Hersey, Paul Mellor, Wei Dai, Alessandra Santos-Silva, Daniel Liber, Louisa Luk, Ian Titley, Craig P Carden, Garry Box, David L. Hudson, Stanley B. Kaye, Robert Brown
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (2): 325–335.
https://doi.org/10.1158/1535-7163.MCT-10-0788
Published: 08 February 2011
View article titled, Ovarian Cancer Stem Cell–Like Side Populations Are Enriched Following Chemotherapy and Overexpress <em>EZH2</em>
Open the PDF for Ovarian Cancer Stem Cell–Like Side Populations Are Enriched Following Chemotherapy and Overexpress <em>EZH2</em> in another window
Includes: Supplementary data
Journal Articles

Dual repair modulation reverses Temozolomide resistance in vitro

Vincent A. Barvaux, Malcolm Ranson, Robert Brown, R. Stanley McElhinney, T. Brian H. McMurry, Geoffrey P. Margison
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (2): 123–127.
https://doi.org/10.1158/1535-7163.123.3.2
Published: 25 February 2004
View article titled, Dual repair modulation reverses Temozolomide resistance <em>in vitro</em>
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Includes: Supplementary data
Journal Articles

Pharmacodynamic Response and Inhibition of Growth of Human Tumor Xenografts by the Novel Histone Deacetylase Inhibitor PXD101

Jane A. Plumb, Paul W. Finn, Robert J. Williams, Morwenna J. Bandara, M. Rosario Romero, Claire J. Watkins, Nicholas B. La Thangue, Robert Brown
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (8): 721–728.
Published: 25 August 2003
View article titled, Pharmacodynamic Response and Inhibition of Growth of Human Tumor Xenografts by the Novel Histone Deacetylase Inhibitor PXD101
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