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Journal Articles

Targeting JAK1/STAT3 Signaling Suppresses Tumor Progression and Metastasis in a Peritoneal Model of Human Ovarian Cancer

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Wei Wen, Wei Liang, Jun Wu, Claudia M. Kowolik, Ralf Buettner, Anna Scuto, Meng-Yin Hsieh, Hao Hong, Christine E. Brown, Stephen J. Forman, David Horne, Robert Morgan, Mark Wakabayashi, Thanh H. Dellinger, Ernest S. Han, John H. Yim, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (12): 3037–3048.
https://doi.org/10.1158/1535-7163.MCT-14-0077
Published: 04 December 2014
View articletitled, Targeting JAK1/STAT3 Signaling Suppresses Tumor Progression and Metastasis in a Peritoneal Model of Human Ovarian Cancer
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Journal Articles

Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3

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Fan Yang, Christine Brown, Ralf Buettner, Michael Hedvat, Renate Starr, Anna Scuto, Anne Schroeder, Michael Jensen, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (4): 953–962.
https://doi.org/10.1158/1535-7163.MCT-09-0947
Published: 07 April 2010
View articletitled, Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3
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Journal Articles

Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas

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Fan Yang, Timothy E. Van Meter, Ralf Buettner, Michael Hedvat, Wei Liang, Claudia M. Kowolik, Nilesh Mepani, Janni Mirosevich, Sangkil Nam, Mike Y. Chen, Gary Tye, Mark Kirschbaum, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (11): 3519–3526.
https://doi.org/10.1158/1535-7163.MCT-08-0138
Published: 11 November 2008
View articletitled, Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas
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Journal Articles

SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells

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Adina Vultur, Ralf Buettner, Claudia Kowolik, Wei Liang, David Smith, Frank Boschelli, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (5): 1185–1194.
https://doi.org/10.1158/1535-7163.MCT-08-0126
Published: 15 May 2008
View articletitled, SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells
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Journal Articles

Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells

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Sangkil Nam, Ann Williams, Adina Vultur, Alan List, Kapil Bhalla, David Smith, Francis Y. Lee, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (4): 1400–1405.
https://doi.org/10.1158/1535-7163.MCT-06-0446
Published: 12 April 2007
View articletitled, Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells
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Journal Articles

Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein

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Anupama Kotha, Madhavi Sekharam, Lucia Cilenti, Khandaker Siddiquee, Annette Khaled, Antonis S. Zervos, Bradford Carter, James Turkson, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (3): 621–629.
https://doi.org/10.1158/1535-7163.MCT-05-0268
Published: 16 March 2006
View articletitled, Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein
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Journal Articles

Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity

Free
James Turkson, Shumin Zhang, Jay Palmer, Heidi Kay, Joseph Stanko, Linda B. Mora, Said Sebti, Hua Yu, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (12): 1533–1542.
https://doi.org/10.1158/1535-7163.1533.3.12
Published: 04 January 2005
View articletitled, Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity
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Journal Articles

Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity

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James Turkson, Joon S. Kim, Shumin Zhang, Jing Yuan, Mei Huang, Matthew Glenn, Eric Haura, Said Sebti, Andrew D. Hamilton, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (3): 261–269.
https://doi.org/10.1158/1535-7163.261.3.3
Published: 16 March 2004
View articletitled, Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity
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Journal Articles

AG490 inhibits G1-S traverse in BALB/c-3T3 cells following either mitogenic stimulation or exogenous expression of E2F-1

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Jason Savell, Yihong Ma, Kristin S. Morrow, Richard Jove, Nancy Olashaw, Pope L. Moseley, W. Douglas Cress, Walker Wharton
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (2): 205–213.
https://doi.org/10.1158/1535-7163.205.3.2
Published: 25 February 2004
View articletitled, AG490 inhibits G1-S traverse in BALB/c-3T3 cells following either mitogenic stimulation or exogenous expression of E2F-1
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Journal Articles

Combination Therapy with AG-490 and Interleukin 12 Achieves Greater Antitumor Effects than Either Agent Alone

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Lyudmila Burdelya, Robyn Catlett-Falcone, Alexander Levitzki, Fengdong Cheng, Linda B. Mora, Eduardo Sotomayor, Domenico Coppola, JiaZhi Sun, Said Sebti, William S. Dalton, Richard Jove, Hua Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (11): 893–899.
Published: 01 September 2002
View articletitled, Combination Therapy with AG-490 and Interleukin 12 Achieves Greater Antitumor Effects than Either Agent Alone
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