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Rebecca Mosher
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Journal Articles

Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody–Drug Conjugate for the Treatment of Cancer

Dorin Toader, Shawn P. Fessler, Scott D. Collins, Patrick R. Conlon, Reddy Bollu, Kalli C. Catcott, Chen-Ni Chin, Anouk Dirksen, Bingfan Du, Jeremy R. Duvall, Stacy Higgins, Mariya V. Kozytska, Kamela Bellovoda, Chelsey Faircloth, David Lee, Fu Li, Liuliang Qin, Caitlin Routhier, Pamela Shaw, Cheri A. Stevenson, Jason Wang, Phonphimon Wongthida, Elena Ter-Ovanesyan, Elizabeth Ditty, Stephen P. Bradley, Ling Xu, Mao Yin, Alexandr V. Yurkovetskiy, Rebecca Mosher, Marc Damelin, Timothy B. Lowinger
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (9): 999–1012.
https://doi.org/10.1158/1535-7163.MCT-22-0786
Published: 05 September 2023
View article titled, Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody–Drug Conjugate for the Treatment of Cancer
Open the PDF for Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody–Drug Conjugate for the Treatment of Cancer in another window
Includes: Supplementary data
Journal Articles

The Dolaflexin-based Antibody–Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b

Natalya D. Bodyak, Rebecca Mosher, Aleksandr V. Yurkovetskiy, Mao Yin, Charlie Bu, Patrick R. Conlon, Damon R. Demady, Michael J. DeVit, Dmitry R. Gumerov, Venu R. Gurijala, Winnie Lee, Dennis McGillicuddy, Peter U. Park, Laura L. Poling, Marina Protopova, LiuLiang Qin, Cheri A. Stevenson, Elena Ter-Ovanesyan, Alex Uttard, Dongmei Xiao, Jian Xu, Ling Xu, Donald A. Bergstrom, Timothy B. Lowinger
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2021) 20 (5): 896–905.
https://doi.org/10.1158/1535-7163.MCT-20-0183
Published: 01 May 2021
View article titled, The Dolaflexin-based Antibody–Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b
Open the PDF for The Dolaflexin-based Antibody–Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b in another window
Includes: Supplementary data
Journal Articles

Abstract A043: NaPi2b expression in a large surgical non-small cell lung cancer cohort

Paul L Mitchell, Hui Yu, Gareth Rivalland, Khashayar Asadi, Rebecca Mosher, Fred Hirsch, Christopher Rivard
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): A043.
https://doi.org/10.1158/1535-7163.TARG-19-A043
Published: 01 December 2019
View article titled, Abstract A043: NaPi2b expression in a large surgical non-small cell lung cancer cohort
Journal Articles

Abstract B119: Relationship of NaPi2b expression and efficacy of XMT-1536, a NaPi2b targeting antibody-drug conjugate (ADC), in an unselected panel of human primary ovarian mouse xenograft models

Rebecca Mosher, Laura Poling, LiuLiang Qin, Natalya Bodyak, Donald Bergstrom
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): B119.
https://doi.org/10.1158/1535-7163.TARG-17-B119
Published: 01 January 2018
View article titled, Abstract B119: Relationship of NaPi2b expression and efficacy of XMT-1536, a NaPi2b targeting antibody-drug conjugate (ADC), in an unselected panel of human primary ovarian mouse xenograft models
Journal Articles

Abstract A41: The preanalytic impact of simulated ischemia on PI3K biomarkers

Lance Ostrom, Rebecca Mosher, Massisimo Loda
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): A41.
https://doi.org/10.1158/1535-7163.TARG-09-A41
Published: 10 December 2009
View article titled, Abstract A41: The preanalytic impact of simulated ischemia on PI3K biomarkers
Journal Articles

Abstract B27: Correlation between TNFα and LCL161 anti‐tumor activity in patient derived xenograft models of human cancer

Brant Firestone, Colleen Conway, Guizhi Yang, Hui Gao, Dale Porter, Joanna Slisz, Dan He, Rebecca Mosher, John Monahan, Christopher Straub, Michael Morrissey, Yung‐mae Yao, Leigh Zawel
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B27.
https://doi.org/10.1158/1535-7163.TARG-09-B27
Published: 10 December 2009
View article titled, Abstract B27: Correlation between TNFα and LCL161 anti‐tumor activity in patient derived xenograft models of human cancer