Page 1 | Search Results | Molecular Cancer Therapeutics | American Association for Cancer Research

1-11 of 11

Sort by

Sort Order Select

Journal Articles

Anticancer Efficacy of KRAS^G12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRAS^G12C-Mutant Pancreatic and Lung Cancers

Mol Cancer Ther (2023) 22 (12): 1422–1433.

https://doi.org/10.1158/1535-7163.MCT-23-0251

Published: 01 December 2023

View article titled, Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers

Includes: Supplementary data

Journal Articles

PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Gabriel B. Mpilla, Md. Hafiz Uddin, Mohammed N. Al-Hallak, Amro Aboukameel, Yiwei Li, Steve H. Kim, Rafic Beydoun, Gregory Dyson, Erkan Baloglu, William T. Senapedis, Yosef Landesman, Kay-Uwe Wagner, Nerissa T. Viola, Bassel F. El-Rayes, Philip A. Philip, Ramzi M. Mohammad, Asfar S. Azmi

Mol Cancer Ther (2021) 20 (10): 1836–1845.

https://doi.org/10.1158/1535-7163.MCT-20-1105

Published: 01 October 2021

View article titled, PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Includes: Supplementary data

Journal Articles

Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma

Amro Aboukameel, Irfana Muqbil, William Senapedis, Erkan Baloglu, Yosef Landesman, Sharon Shacham, Michael Kauffman, Philip A. Philip, Ramzi M. Mohammad, Asfar S. Azmi

Mol Cancer Ther (2017) 16 (1): 76–87.

https://doi.org/10.1158/1535-7163.MCT-16-0205

Published: 05 January 2017

View article titled, Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma

Includes: Supplementary data

Journal Articles

A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Fardokht Abulwerdi, Chenzhong Liao, Meilan Liu, Asfar S. Azmi, Amro Aboukameel, Ahmed S.A. Mady, Thippeswamy Gulappa, Tomasz Cierpicki, Scott Owens, Tao Zhang, Duxin Sun, Jeanne A. Stuckey, Ramzi M. Mohammad, Zaneta Nikolovska-Coleska

Mol Cancer Ther (2014) 13 (3): 565–575.

https://doi.org/10.1158/1535-7163.MCT-12-0767

Published: 09 March 2014

View article titled, A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Includes: Supplementary data

Journal Articles

Proof of Concept: Network and Systems Biology Approaches Aid in the Discovery of Potent Anticancer Drug Combinations

Asfar S. Azmi, Zhiwei Wang, Philip A. Philip, Ramzi M. Mohammad, Fazlul H. Sarkar

Mol Cancer Ther (2010) 9 (12): 3137–3144.

https://doi.org/10.1158/1535-7163.MCT-10-0642

Published: 14 December 2010

View article titled, Proof of Concept: Network and Systems Biology Approaches Aid in the Discovery of Potent Anticancer Drug Combinations

Journal Articles

ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells

Jyoti Nautiyal, Yingjie Yu, Amro Aboukameel, Shailender S. Kanwar, Jayanta K. Das, Jianhua Du, Bhaumik B. Patel, Fazlul H. Sarkar, Arun K. Rishi, Ramzi M. Mohammad, Adhip P.N. Majumdar

Mol Cancer Ther (2010) 9 (6): 1503–1514.

https://doi.org/10.1158/1535-7163.MCT-10-0019

Published: 09 June 2010

View article titled, ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells

Includes: Supplementary data

Journal Articles

Critical role of prostate apoptosis response-4 in determining the sensitivity of pancreatic cancer cells to small-molecule inhibitor-induced apoptosis

Asfar Sohail Azmi, Zhiwei Wang, Ravshan Burikhanov, Vivek M. Rangnekar, Guoping Wang, Jianyong Chen, Shaomeng Wang, Fazlul H. Sarkar, Ramzi M. Mohammad

Mol Cancer Ther (2008) 7 (9): 2884–2893.

https://doi.org/10.1158/1535-7163.MCT-08-0438

Published: 11 September 2008

View article titled, Critical role of prostate apoptosis response-4 in determining the sensitivity of pancreatic cancer cells to small-molecule inhibitor-induced apoptosis

Journal Articles

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X_L [(−)-gossypol] against diffuse large cell lymphoma

Ramzi M. Mohammad, Shaomeng Wang, Amro Aboukameel, Ben Chen, Xihan Wu, Jianyong Chen, Ayad Al-Katib

Mol Cancer Ther (2005) 4 (1): 13–21.

https://doi.org/10.1158/1535-7163.13.4.1

Published: 18 January 2005

View article titled, Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL [(−)-gossypol] against diffuse large cell lymphoma

Journal Articles

Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy

Ramzi M. Mohammad, Ayad Al-Katib, Amro Aboukameel, Daniel R. Doerge, Fazlul Sarkar, Omer Kucuk

Mol Cancer Ther (2003) 2 (12): 1361–1368.

Published: 05 January 2004

View article titled, Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy

Journal Articles

2-[4-(7-Chloro-2-quinoxalinyloxy)phenoxy]-propionic Acid (XK469), an Inhibitor of Topoisomerase (Topo) IIβ, Up-Regulates Topo IIα and Enhances Topo IIα-mediated Cytotoxicity

Edith J. Mensah-Osman, Ayad M. Al-Katib, Hai-Young Wu, Nadir I. Osman, Ramzi M. Mohammad

Mol Cancer Ther (2002) 1 (14): 1321–1326.

Published: 01 December 2002

View article titled, 2-[4-(7-Chloro-2-quinoxalinyloxy)phenoxy]-propionic Acid (XK469), an Inhibitor of Topoisomerase (Topo) IIβ, Up-Regulates Topo IIα and Enhances Topo IIα-mediated Cytotoxicity

Journal Articles

2-[4-(7-Chloro-2-quinoxalinyloxy)phenoxy]-propionic Acid (XK469) Inhibition of Topoisomerase IIβ Is Not Sufficient for Therapeutic Response in Human Waldenstrom’s Macroglobulinemia Xenograft Model

Edith J. Mensah-Osman, Ayad M. Al-Katib, Mahmoud H. Dandashi, Ramzi M. Mohammad

Mol Cancer Ther (2002) 1 (14): 1315–1320.

Published: 01 December 2002

View article titled, 2-[4-(7-Chloro-2-quinoxalinyloxy)phenoxy]-propionic Acid (XK469) Inhibition of Topoisomerase IIβ Is Not Sufficient for Therapeutic Response in Human Waldenstrom’s Macroglobulinemia Xenograft Model

NARROW

Anticancer Efficacy of KRAS^G12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRAS^G12C-Mutant Pancreatic and Lung Cancers

PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma

A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Proof of Concept: Network and Systems Biology Approaches Aid in the Discovery of Potent Anticancer Drug Combinations

ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells

Critical role of prostate apoptosis response-4 in determining the sensitivity of pancreatic cancer cells to small-molecule inhibitor-induced apoptosis

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X_L [(−)-gossypol] against diffuse large cell lymphoma

Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy

2-[4-(7-Chloro-2-quinoxalinyloxy)phenoxy]-propionic Acid (XK469), an Inhibitor of Topoisomerase (Topo) IIβ, Up-Regulates Topo IIα and Enhances Topo IIα-mediated Cytotoxicity

2-[4-(7-Chloro-2-quinoxalinyloxy)phenoxy]-propionic Acid (XK469) Inhibition of Topoisomerase IIβ Is Not Sufficient for Therapeutic Response in Human Waldenstrom’s Macroglobulinemia Xenograft Model

Email alerts

AACR Journals

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only