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Journal Articles

Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling

Dhanya K. Nambiar, Paulraj Rajamani, Gagan Deep, Anil K. Jain, Rajesh Agarwal, Rana P. Singh

Mol Cancer Ther (2015) 14 (12): 2722–2734.

https://doi.org/10.1158/1535-7163.MCT-15-0348

Published: 06 December 2015

View article titled, Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling

Includes: Supplementary data

Journal Articles

Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

Manjinder Kaur, Balaiya Velmurugan, Alpna Tyagi, Gagan Deep, Suchitra Katiyar, Chapla Agarwal, Rajesh Agarwal

Mol Cancer Ther (2009) 8 (8): 2366–2374.

https://doi.org/10.1158/1535-7163.MCT-09-0304

Published: 14 August 2009

View article titled, Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

Journal Articles

Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells

Manesh Chittezhath, Gagan Deep, Rana P. Singh, Chapla Agarwal, Rajesh Agarwal

Mol Cancer Ther (2008) 7 (7): 1817–1826.

https://doi.org/10.1158/1535-7163.MCT-08-0256

Published: 21 July 2008

View article titled, Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells

Journal Articles

Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice

Komal Raina, Subapriya Rajamanickam, Gagan Deep, Meenakshi Singh, Rajesh Agarwal, Chapla Agarwal

Mol Cancer Ther (2008) 7 (5): 1258–1267.

https://doi.org/10.1158/1535-7163.MCT-07-2220

Published: 15 May 2008

View article titled, Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice

Journal Articles

Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine–induced urinary bladder carcinogenesis in male ICR mice

Alpna Tyagi, Komal Raina, Rana P. Singh, Mallikarjuna Gu, Chapla Agarwal, Gail Harrison, L. Michael Glode, Rajesh Agarwal

Mol Cancer Ther (2007) 6 (12): 3248–3255.

https://doi.org/10.1158/1535-7163.MCT-07-2006

Published: 18 December 2007

View article titled, Chemopreventive effects of silymarin and silibinin on <em>N</em>-butyl-<em>N</em>-(4-hydroxybutyl) nitrosamine–induced urinary bladder carcinogenesis in male ICR mice

Journal Articles

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells

Srirupa Roy, Manjinder Kaur, Chapla Agarwal, Marianne Tecklenburg, Robert A. Sclafani, Rajesh Agarwal

Mol Cancer Ther (2007) 6 (10): 2696–2707.

https://doi.org/10.1158/1535-7163.MCT-07-0104

Published: 15 October 2007

View article titled, p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells

Journal Articles

Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells

Chapla Agarwal, Alpna Tyagi, Rajesh Agarwal

Mol Cancer Ther (2006) 5 (12): 3294–3302.

https://doi.org/10.1158/1535-7163.MCT-06-0483

Published: 15 December 2006

View article titled, Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells

Journal Articles

Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice

Mallikarjuna Gu, Rana P. Singh, Sivanandhan Dhanalakshmi, Sarumathi Mohan, Rajesh Agarwal

Mol Cancer Ther (2006) 5 (8): 2121–2129.

https://doi.org/10.1158/1535-7163.MCT-06-0052

Published: 23 August 2006

View article titled, Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice

Journal Articles

Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated–p53 activation

Manjinder Kaur, Rajesh Agarwal, Chapla Agarwal

Mol Cancer Ther (2006) 5 (5): 1265–1274.

https://doi.org/10.1158/1535-7163.MCT-06-0014

Published: 26 May 2006

View article titled, Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated–p53 activation

Journal Articles

Silibinin inhibits UVB- and epidermal growth factor–induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-κB in mouse epidermal JB6 cells

Rana P. Singh, Sivanandhan Dhanalakshmi, Sarumathi Mohan, Chapla Agarwal, Rajesh Agarwal

Mol Cancer Ther (2006) 5 (5): 1145–1153.

https://doi.org/10.1158/1535-7163.MCT-05-0478

Published: 26 May 2006

View article titled, Silibinin inhibits UVB- and epidermal growth factor–induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-κB in mouse epidermal JB6 cells

Journal Articles

Inhibition of Retinoblastoma Protein (Rb) Phosphorylation at Serine Sites and an Increase in Rb-E2F Complex Formation by Silibinin in Androgen-dependent Human Prostate Carcinoma LNCaP Cells: Role in Prostate Cancer Prevention

Alpana Tyagi, Chapla Agarwal, Rajesh Agarwal

Mol Cancer Ther (2002) 1 (7): 525–532.

Published: 01 May 2002

View article titled, Inhibition of Retinoblastoma Protein (Rb) Phosphorylation at Serine Sites and an Increase in Rb-E2F Complex Formation by Silibinin in Androgen-dependent Human Prostate Carcinoma LNCaP Cells: Role in Prostate Cancer Prevention

NARROW

Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling

Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells

Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice

Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine–induced urinary bladder carcinogenesis in male ICR mice

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells

Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells

Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice

Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated–p53 activation

Silibinin inhibits UVB- and epidermal growth factor–induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-κB in mouse epidermal JB6 cells

Inhibition of Retinoblastoma Protein (Rb) Phosphorylation at Serine Sites and an Increase in Rb-E2F Complex Formation by Silibinin in Androgen-dependent Human Prostate Carcinoma LNCaP Cells: Role in Prostate Cancer Prevention

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