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Pedro J. Beltran
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Journal Articles

Abstract A084: Use of the natural nucleotide, GTP, is essential for the identification of potent, active-state KRASG12C inhibitors that bind in the switch II pocket

Bin Wang, Alok Sharma, James Stice, Brian Smith, Marcin Dyba, Devansh Singh, John-Paul Denson, Dana Rabara, Erik Larsen, Yue Yang, Felice C Lightstone, Andrew Stephen, Dwight Nissley, Frank McCormick, Eli Wallace, Anna E Maciag, Pedro J Beltran
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): A084.
https://doi.org/10.1158/1535-7163.TARG-23-A084
Published: 01 December 2023
View article titled, Abstract A084: Use of the natural nucleotide, GTP, is essential for the identification of potent, active-state KRAS<sup>G12C</sup> inhibitors that bind in the switch II pocket
Journal Articles

Targeting IGF-IR with Ganitumab Inhibits Tumorigenesis and Increases Durability of Response to Androgen-Deprivation Therapy in VCaP Prostate Cancer Xenografts

Cale D. Fahrenholtz, Pedro J. Beltran, Kerry L. Burnstein
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (4): 394–404.
https://doi.org/10.1158/1535-7163.MCT-12-0648
Published: 08 April 2013
View article titled, Targeting IGF-IR with Ganitumab Inhibits Tumorigenesis and Increases Durability of Response to Androgen-Deprivation Therapy in VCaP Prostate Cancer Xenografts
Open the PDF for Targeting IGF-IR with Ganitumab Inhibits Tumorigenesis and Increases Durability of Response to Androgen-Deprivation Therapy in VCaP Prostate Cancer Xenografts in another window
Includes: Supplementary data
Journal Articles

Effect of a Low-Fat Diet Combined with IGF-1 Receptor Blockade on 22Rv1 Prostate Cancer Xenografts

Ramdev Konijeti, Satomi Koyama, Ashley Gray, R. James Barnard, Jonathan W. Said, Brandon Castor, David Elashoff, Junxiang Wan, Pedro J. Beltran, Frank J. Calzone, Pinchas Cohen, Colette Galet, William J. Aronson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (7): 1539–1546.
https://doi.org/10.1158/1535-7163.MCT-11-1003
Published: 05 July 2012
View article titled, Effect of a Low-Fat Diet Combined with IGF-1 Receptor Blockade on 22Rv1 Prostate Cancer Xenografts
Open the PDF for Effect of a Low-Fat Diet Combined with IGF-1 Receptor Blockade on 22Rv1 Prostate Cancer Xenografts in another window
Journal Articles

Abstract C55: Ganitumab (AMG 479) inhibits the development and progression of castration-resistant VCaP human prostate cancer xenografts.

Cale D. Fahrenholtz, Pedro J. Beltran, Frank J. Calzone, Kerry L. Burnstein
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): C55.
https://doi.org/10.1158/1535-7163.TARG-11-C55
Published: 12 November 2011
View article titled, Abstract C55: Ganitumab (AMG 479) inhibits the development and progression of castration-resistant VCaP human prostate cancer xenografts.
Journal Articles

Selective and Potent Raf Inhibitors Paradoxically Stimulate Normal Cell Proliferation and Tumor Growth

Josette Carnahan, Pedro J. Beltran, Carol Babij, Quynh Le, Mark J. Rose, Steven Vonderfecht, Joseph L. Kim, Adrian L. Smith, Karthik Nagapudi, Martin A. Broome, Manory Fernando, Hue Kha, Brian Belmontes, Robert Radinsky, Richard Kendall, Teresa L. Burgess
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (8): 2399–2410.
https://doi.org/10.1158/1535-7163.MCT-10-0181
Published: 09 August 2010
View article titled, Selective and Potent Raf Inhibitors Paradoxically Stimulate Normal Cell Proliferation and Tumor Growth
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Includes: Supplementary data
Journal Articles

Abstract C172: Efficacy of AMG 479, alone and in combination with cisplatin, in ovarian carcinoma xenograft models

Pedro J. Beltran, Petia Mitchell, Elaina Cajulis, Gordon Moody, Young‐Ah Chung, Jon Wang, Brian Belmontes, Robert Radinsky, Frank J. Calzone
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): C172.
https://doi.org/10.1158/1535-7163.TARG-09-C172
Published: 10 December 2009
View article titled, Abstract C172: Efficacy of AMG 479, alone and in combination with cisplatin, in ovarian carcinoma xenograft models
Journal Articles

AMG 479, a fully human anti–insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells

Pedro J. Beltran, Petia Mitchell, Young-A Chung, Elaina Cajulis, John Lu, Brian Belmontes, Joanne Ho, Mei Mei Tsai, Min Zhu, Steven Vonderfecht, Renato Baserga, Richard Kendall, Robert Radinsky, Frank J. Calzone
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (5): 1095–1105.
https://doi.org/10.1158/1535-7163.MCT-08-1171
Published: 13 May 2009
View article titled, AMG 479, a fully human anti–insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells
Open the PDF for AMG 479, a fully human anti–insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells in another window
Includes: Supplementary data