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Journal Articles

Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis

Anjan K. Pradhan, Jinkal Modi, Santanu Maji, Amit Kumar, Praveen Bhoopathi, Padmanabhan Mannangatti, Chunqing Guo, Daniel K. Afosah, Mark C. Mochel, Nitai D. Mukhopadhyay, John M. Kirkwood, Xiang-Yang Wang, Umesh R. Desai, Devanand Sarkar, Luni Emdad, Swadesh K. Das, Paul B. Fisher

Mol Cancer Ther (2023) 22 (10): 1115–1127.

https://doi.org/10.1158/1535-7163.MCT-22-0653

Published: 02 October 2023

View articletitled, Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis

Includes: Supplementary data

Journal Articles

Suppression of Prostate Cancer Pathogenesis Using an MDA-9/Syntenin (SDCBP) PDZ1 Small-Molecule Inhibitor

Swadesh K. Das, Timothy P. Kegelman, Anjan K. Pradhan, Xue-Ning Shen, Praveen Bhoopathi, Sarmistha Talukdar, Santanu Maji, Devanand Sarkar, Luni Emdad, Paul B. Fisher

Mol Cancer Ther (2019) 18 (11): 1997–2007.

https://doi.org/10.1158/1535-7163.MCT-18-1019

Published: 01 November 2019

View articletitled, Suppression of Prostate Cancer Pathogenesis Using an MDA-9/Syntenin (SDCBP) PDZ1 Small-Molecule Inhibitor

Includes: Supplementary data

Journal Articles

Recombinant MDA-7/IL24 Suppresses Prostate Cancer Bone Metastasis through Downregulation of the Akt/Mcl-1 Pathway

Anjan K. Pradhan, Praveen Bhoopathi, Sarmistha Talukdar, Xue-Ning Shen, Luni Emdad, Swadesh K. Das, Devanand Sarkar, Paul B. Fisher

Mol Cancer Ther (2018) 17 (9): 1951–1960.

https://doi.org/10.1158/1535-7163.MCT-17-1002

Published: 04 September 2018

View articletitled, Recombinant MDA-7/IL24 Suppresses Prostate Cancer Bone Metastasis through Downregulation of the Akt/Mcl-1 Pathway

Includes: Supplementary data

Journal Articles

In Situ Vaccination with CD204 Gene-Silenced Dendritic Cell, not Unmodified Dendritic Cell, Enhances Radiation Therapy of Prostate Cancer

Chunqing Guo, Huanfa Yi, Xiaofei Yu, Daming Zuo, Jie Qian, Gary Yang, Barbara A. Foster, John R. Subjeck, Xiaolei Sun, Ross B. Mikkelsen, Paul B. Fisher, Xiang-Yang Wang

Mol Cancer Ther (2012) 11 (11): 2331–2341.

https://doi.org/10.1158/1535-7163.MCT-12-0164

Published: 08 November 2012

View articletitled, In Situ Vaccination with CD204 Gene-Silenced Dendritic Cell, not Unmodified Dendritic Cell, Enhances Radiation Therapy of Prostate Cancer

Includes: Supplementary data

Journal Articles

17-Allylamino-17-Demethoxygeldanamycin and MEK1/2 Inhibitors Kill GI Tumor Cells via Ca²⁺-Dependent Suppression of GRP78/BiP and Induction of Ceramide and Reactive Oxygen Species

Teneille Walker, Clint Mitchell, Margaret A. Park, Adly Yacoub, Mohamed Rahmani, Dieter Häussinger, Roland Reinehr, Christina Voelkel-Johnson, Paul B. Fisher, Steven Grant, Paul Dent

Mol Cancer Ther (2010) 9 (5): 1378–1395.

https://doi.org/10.1158/1535-7163.MCT-09-1131

Published: 09 May 2010

View articletitled, 17-Allylamino-17-Demethoxygeldanamycin and MEK1/2 Inhibitors Kill GI Tumor Cells via Ca2+-Dependent Suppression of GRP78/BiP and Induction of Ceramide and Reactive Oxygen Species

Includes: Supplementary data

Journal Articles

Astrocyte Elevated Gene-1: A Novel Target for Human Glioma Therapy

Luni Emdad, Devanand Sarkar, Seok-Geun Lee, Zhao Zhong Su, Byoung Kwon Yoo, Rupesh Dash, Adly Yacoub, Christine E. Fuller, Khalid Shah, Paul Dent, Jeffrey N. Bruce, Paul B. Fisher

Mol Cancer Ther (2010) 9 (1): 79–88.

https://doi.org/10.1158/1535-7163.MCT-09-0752

Published: 12 January 2010

View articletitled, Astrocyte Elevated Gene-1: A Novel Target for Human Glioma Therapy

Journal Articles

MDA-7/IL-24–induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK–dependent mechanism

Margaret A. Park, Teneille Walker, Aditi Pandya Martin, Jeremy Allegood, Nicollaq Vozhilla, Luni Emdad, Devanand Sarkar, Mohammed Rahmani, Martin Graf, Adly Yacoub, Costas Koumenis, Sarah Spiegel, David T. Curiel, Christina Voelkel-Johnson, Steven Grant, Paul B. Fisher, Paul Dent

Mol Cancer Ther (2009) 8 (5): 1280–1291.

https://doi.org/10.1158/1535-7163.MCT-09-0073

Published: 13 May 2009

View articletitled, MDA-7/IL-24–induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK–dependent mechanism

Includes: Supplementary data

Journal Articles

Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95

Margaret A. Park, Guo Zhang, Clint Mitchell, Mohamed Rahmani, Hossein Hamed, Michael P. Hagan, Adly Yacoub, David T. Curiel, Paul B. Fisher, Steven Grant, Paul Dent

Mol Cancer Ther (2008) 7 (9): 2633–2648.

https://doi.org/10.1158/1535-7163.MCT-08-0400

Published: 11 September 2008

View articletitled, Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95

Includes: Supplementary data

Journal Articles

Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis

Irina V. Lebedeva, Zhao-zhong Su, Nichollaq Vozhilla, Lejuan Chatman, Devanand Sarkar, Paul Dent, Mohammad Athar, Paul B. Fisher

Mol Cancer Ther (2008) 7 (7): 2042–2050.

https://doi.org/10.1158/1535-7163.MCT-08-0245

Published: 21 July 2008

View articletitled, Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis

Journal Articles

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

Adly Yacoub, Margaret A. Park, Pankaj Gupta, Mohammed Rahmani, Guo Zhang, Hossein Hamed, David Hanna, Devanand Sarkar, Irina V. Lebedeva, Luni Emdad, Moira Sauane, Nicollaq Vozhilla, Sarah Spiegel, Costas Koumenis, Martin Graf, David T. Curiel, Steven Grant, Paul B. Fisher, Paul Dent

Mol Cancer Ther (2008) 7 (2): 297–313.

https://doi.org/10.1158/1535-7163.MCT-07-2166

Published: 15 February 2008

View articletitled, Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

Journal Articles

Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling

Adly Yacoub, Pankaj Gupta, Margaret A. Park, Mohammed Rhamani, Hossein Hamed, David Hanna, Guo Zhang, Devanand Sarkar, Irina V. Lebedeva, Luni Emdad, Costas Koumenis, David T. Curiel, Steven Grant, Paul B. Fisher, Paul Dent

Mol Cancer Ther (2008) 7 (2): 314–329.

https://doi.org/10.1158/1535-7163.MCT-07-2150

Published: 15 February 2008

View articletitled, Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling

Journal Articles

Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells

Clint Mitchell, Maragret A. Park, Guo Zhang, Adly Yacoub, David T. Curiel, Paul B. Fisher, John D. Roberts, Steven Grant, Paul Dent

Mol Cancer Ther (2007) 6 (12): 3101–3112.

https://doi.org/10.1158/1535-7163.MCT-07-0561

Published: 18 December 2007

View articletitled, Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells

Journal Articles

Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells

Luni Emdad, Irina V. Lebedeva, Zao-Zhong Su, Devanand Sarkar, Paul Dent, David T. Curiel, Paul B. Fisher

Mol Cancer Ther (2007) 6 (11): 2985–2994.

https://doi.org/10.1158/1535-7163.MCT-07-0399

Published: 19 November 2007

View articletitled, Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells

Journal Articles

Radiation-induced cell signaling: inside-out and outside-in

Kristoffer Valerie, Adly Yacoub, Michael P. Hagan, David T. Curiel, Paul B. Fisher, Steven Grant, Paul Dent

Mol Cancer Ther (2007) 6 (3): 789–801.

https://doi.org/10.1158/1535-7163.MCT-06-0596

Published: 15 March 2007

View articletitled, Radiation-induced cell signaling: inside-out and outside-in

Journal Articles

Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus

Matthew A. Tyler, Ilya V. Ulasov, Anton Borovjagin, Adam M. Sonabend, Andrey Khramtsov, Yu Han, Paul Dent, Paul B. Fisher, David T. Curiel, Maciej S. Lesniak

Mol Cancer Ther (2006) 5 (9): 2408–2416.

https://doi.org/10.1158/1535-7163.MCT-06-0187

Published: 19 September 2006

View articletitled, Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus

Journal Articles

MDA-7 (Interleukin-24) Inhibits the Proliferation of Renal Carcinoma Cells and Interacts with Free Radicals to Promote Cell Death and Loss of Reproductive Capacity

Adly Yacoub, Clint Mitchell, Jessica Brannon, Elizabeth Rosenberg, Liang Qiao, Robert McKinstry, W. Marston Linehan, Zao-shong Su, Devanand Sarkar, Irina V. Lebedeva, Kristoffer Valerie, Rahul V. Gopalkrishnan, Steven Grant, Paul B. Fisher, Paul Dent

Mol Cancer Ther (2003) 2 (7): 623–632.

Published: 25 July 2003

View articletitled, MDA-7 (Interleukin-24) Inhibits the Proliferation of Renal Carcinoma Cells and Interacts with Free Radicals to Promote Cell Death and Loss of Reproductive Capacity

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Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis

Suppression of Prostate Cancer Pathogenesis Using an MDA-9/Syntenin (SDCBP) PDZ1 Small-Molecule Inhibitor

Recombinant MDA-7/IL24 Suppresses Prostate Cancer Bone Metastasis through Downregulation of the Akt/Mcl-1 Pathway

In Situ Vaccination with CD204 Gene-Silenced Dendritic Cell, not Unmodified Dendritic Cell, Enhances Radiation Therapy of Prostate Cancer

17-Allylamino-17-Demethoxygeldanamycin and MEK1/2 Inhibitors Kill GI Tumor Cells via Ca²⁺-Dependent Suppression of GRP78/BiP and Induction of Ceramide and Reactive Oxygen Species

Astrocyte Elevated Gene-1: A Novel Target for Human Glioma Therapy

MDA-7/IL-24–induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK–dependent mechanism

Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95

Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells

Regulation of GST-MDA-7 toxicity in human glioblastoma cells by ERBB1, ERK1/2, PI3K, and JNK1-3 pathway signaling

Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells

Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells

Radiation-induced cell signaling: inside-out and outside-in

Enhanced transduction of malignant glioma with a double targeted Ad5/3-RGD fiber-modified adenovirus

MDA-7 (Interleukin-24) Inhibits the Proliferation of Renal Carcinoma Cells and Interacts with Free Radicals to Promote Cell Death and Loss of Reproductive Capacity

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