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Patrick Chène
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Journal Articles

Characterization of the Novel and Specific PI3Kα Inhibitor NVP-BYL719 and Development of the Patient Stratification Strategy for Clinical Trials

Christine Fritsch, Alan Huang, Christian Chatenay-Rivauday, Christian Schnell, Anupama Reddy, Manway Liu, Audrey Kauffmann, Daniel Guthy, Dirk Erdmann, Alain De Pover, Pascal Furet, Hui Gao, Stephane Ferretti, Youzhen Wang, Joerg Trappe, Saskia M. Brachmann, Sauveur-Michel Maira, Christopher Wilson, Markus Boehm, Carlos Garcia-Echeverria, Patrick Chene, Marion Wiesmann, Robert Cozens, Joseph Lehar, Robert Schlegel, Giorgio Caravatti, Francesco Hofmann, William R. Sellers
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2014) 13 (5): 1117–1129.
https://doi.org/10.1158/1535-7163.MCT-13-0865
Published: 05 May 2014
View article titled, Characterization of the Novel and Specific PI3Kα Inhibitor NVP-BYL719 and Development of the Patient Stratification Strategy for Clinical Trials
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Includes: Supplementary data
Journal Articles

Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor

Sauveur-Michel Maira, Sabina Pecchi, Alan Huang, Matthew Burger, Mark Knapp, Dario Sterker, Christian Schnell, Daniel Guthy, Tobi Nagel, Marion Wiesmann, Saskia Brachmann, Christine Fritsch, Marion Dorsch, Patrick Chène, Kevin Shoemaker, Alain De Pover, Daniel Menezes, Georg Martiny-Baron, Doriano Fabbro, Christopher J. Wilson, Robert Schlegel, Francesco Hofmann, Carlos García-Echeverría, William R. Sellers, Charles F. Voliva
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (2): 317–328.
https://doi.org/10.1158/1535-7163.MCT-11-0474
Published: 08 February 2012
View article titled, Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor
Open the PDF for Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor in another window
Includes: Supplementary data
Journal Articles

Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805

Fabienne Baffert, Catherine H. Régnier, Alain De Pover, Carole Pissot-Soldermann, Gisele A. Tavares, Francesca Blasco, Josef Brueggen, Patrick Chène, Peter Drueckes, Dirk Erdmann, Pascal Furet, Marc Gerspacher, Marc Lang, David Ledieu, Lynda Nolan, Stephan Ruetz, Joerg Trappe, Eric Vangrevelinghe, Markus Wartmann, Lorenza Wyder, Francesco Hofmann, Thomas Radimerski
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (7): 1945–1955.
https://doi.org/10.1158/1535-7163.MCT-10-0053
Published: 07 July 2010
View article titled, Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805
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Includes: Supplementary data
Journal Articles

Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800

Andrew J. Massey, Joseph Schoepfer, Paul A. Brough, Josef Brueggen, Patrick Chène, Martin J. Drysdale, Ulrike Pfaar, Thomas Radimerski, Stephan Ruetz, Alain Schweitzer, Mike Wood, Carlos Garcia-Echeverria, Michael Rugaard Jensen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (4): 906–919.
https://doi.org/10.1158/1535-7163.MCT-10-0055
Published: 07 April 2010
View article titled, Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800
Open the PDF for Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800 in another window
Includes: Supplementary data
Journal Articles

NVP-AUY922: A novel small molecule HSP90 inhibitor with potent in vivo antitumor efficacy

Michael Rugaard Jensen, Joseph Schoepfer, Thomas Radimersky, Andrew Massey, Josef Brueggen, Alain Schweitzer, Ulrike Pfaar, Stephan Ruetz, Chantal Guy, Alan Buckler, Christian Schnell, Robert Cozens, Paul Brough, Martin Drysdale, Cornelia Quadt, Carlos Garcia-Echeverria, Patrick Chene
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B279.
Published: 01 November 2007
View article titled, NVP-AUY922: A novel small molecule HSP90 inhibitor with potent <em>in vivo</em> antitumor efficacy