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Paolo Orsini
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Journal Articles

Novel Thienoduocarmycin–Trastuzumab ADC Demonstrates Strong Antitumor Efficacy with Favorable Safety Profile in Preclinical Studies

Barbara Valsasina, Paolo Orsini, Michele Caruso, Clara Albanese, Antonella Ciavolella, Ulisse Cucchi, Ivan Fraietta, Nicola Melillo, Francesco Fiorentini, Simona Rizzi, Matteo Salsa, Antonella Isacchi, Fabio Gasparri
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12): 1465–1478.
https://doi.org/10.1158/1535-7163.MCT-23-0315
Published: 01 December 2023
View article titled, Novel Thienoduocarmycin–Trastuzumab ADC Demonstrates Strong Antitumor Efficacy with Favorable Safety Profile in Preclinical Studies
Open the PDF for Novel Thienoduocarmycin–Trastuzumab ADC Demonstrates Strong Antitumor Efficacy with Favorable Safety Profile in Preclinical Studies in another window
Includes: Supplementary data
Journal Articles

Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Elena Ardini, Maria Menichincheri, Patrizia Banfi, Roberta Bosotti, Cristina De Ponti, Romana Pulci, Dario Ballinari, Marina Ciomei, Gemma Texido, Anna Degrassi, Nilla Avanzi, Nadia Amboldi, Maria Beatrice Saccardo, Daniele Casero, Paolo Orsini, Tiziano Bandiera, Luca Mologni, David Anderson, Ge Wei, Jason Harris, Jean-Michel Vernier, Gang Li, Eduard Felder, Daniele Donati, Antonella Isacchi, Enrico Pesenti, Paola Magnaghi, Arturo Galvani
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (4): 628–639.
https://doi.org/10.1158/1535-7163.MCT-15-0758
Published: 05 April 2016
View article titled, Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications
Open the PDF for Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications in another window
Includes: Supplementary data
Journal Articles

Abstract A149: NMS-P945, a highly active payload for antibody drug conjugates generation

Fabio Gasparri, Michele Caruso, Italo Beria, Nicoletta Colombo, Paolo Orsini, Rita Perego, Simona Rizzi, Ulisse Cucchi, Sonia Troiani, Federico Riccardi Sirtori, Clara Albanese, Aurelio Marsiglio, Ivan Fraietta, Francesco Sola, Marina Ciomei, Sabrina Cribioli, Carlo Visco, Eduard Rudolf Felder, Antonella Isacchi, Enrico Pesenti, Arturo Galvani, Daniele Donati, Barbara Valsasina
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A149.
https://doi.org/10.1158/1535-7163.TARG-15-A149
Published: 01 December 2015
View article titled, Abstract A149: NMS-P945, a highly active payload for antibody drug conjugates generation
Journal Articles

Abstract A243: Characterization of NMS‐E628, a small molecule inhibitor of anaplastic lymphoma kinase with antitumor efficacy in ALK‐dependent lymphoma and non‐small cell lung cancer models

Elena Ardini, Maria Menichincheri, Cristina De Ponti, Nadia Amboldi, Maria Beatrice Saccardo, Gemma Texido, Micaela Russo, Paolo Orsini, Tiziano Bandiera, Andrea Lombardi Borgia, Antonella Isacchi, Enrico Pesenti, Francesco Colotta, Paola Magnaghi,, Arturo Galvani, Nerviano Medical
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): A244.
https://doi.org/10.1158/1535-7163.TARG-09-A244
Published: 10 December 2009
View article titled, Abstract A243: Characterization of NMS‐E628, a small molecule inhibitor of anaplastic lymphoma kinase with antitumor efficacy in ALK‐dependent lymphoma and non‐small cell lung cancer models
Journal Articles

Cdc7 kinase inhibitors: 7-Substituted pyrrolopyridinones as potent and orally active antitumor agents

maria menichincheri, Alberto Bargiotti, Jens Berthelsen, Roberto Bossi, Antonella Ciavolella, Alessandra Cirla, Cinzia Cristiani, Valter Croci, Roberto D' Alessio, Barbara Forte, Katia Martina, Antonio Molinari, Alessia Montagnoli, Paolo Orsini, Fabrizio Orzi, Daniele Pezzetta, Antonio Pillan, Italo Poggesi, Fulvia Roletto, Corrado Santocanale, Alessandra Scolaro, Marcellino Tibolla, Barbara Valsasina, Daniele Volpi, Ermes Vanotti
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A224.
Published: 01 November 2007
View article titled, Cdc7 kinase inhibitors: 7-Substituted pyrrolopyridinones as potent and orally active antitumor agents