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Pankaj K. Singh
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Journal Articles

IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer

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Spas Dimitrov Markov, Thomas C. Caffrey, Kelly A. O'Connell, James A. Grunkemeyer, Simon Shin, Ryan Hanson, Prathamesh P. Patil, Surendra K. Shukla, Daisy Gonzalez, Ayrianne J. Crawford, Krysten E. Vance, Ying Huang, Kirsten C. Eberle, Prakash Radhakrishnan, Paul M. Grandgenett, Pankaj K. Singh, Ragupathy Madiyalakan, Tracy R. Daniels-Wells, Manuel L. Penichet, Christopher F. Nicodemus, Jill A. Poole, Elizabeth M. Jaffee, Michael A. Hollingsworth, Kamiya Mehla
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12): 2457–2468.
https://doi.org/10.1158/1535-7163.MCT-21-0368
Published: 03 December 2021
View article titled, IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer
Open the PDF for IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria

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Christopher W. Schultz, Grace A. McCarthy, Teena Nerwal, Avinoam Nevler, James B. DuHadaway, Matthew D. McCoy, Wei Jiang, Samantha Z. Brown, Austin Goetz, Aditi Jain, Valerie S. Calvert, Vikalp Vishwakarma, Dezhen Wang, Ranjan Preet, Joel Cassel, Ross Summer, Hoora Shaghaghi, Yves Pommier, Simone A. Baechler, Michael J. Pishvaian, Talia Golan, Charles J. Yeo, Emanuel F. Petricoin, George C. Prendergast, Joseph Salvino, Pankaj K. Singh, Dan A. Dixon, Jonathan R. Brody
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (11): 2166–2176.
https://doi.org/10.1158/1535-7163.MCT-20-0652
Published: 01 November 2021
View article titled, The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria
Open the PDF for The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria in another window
Includes: Supplementary data
Journal Articles

Exploiting Arginine Auxotrophy with Pegylated Arginine Deiminase (ADI-PEG20) to Sensitize Pancreatic Cancer to Radiotherapy via Metabolic Dysregulation

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Pankaj K. Singh, Amit A. Deorukhkar, Bhanu P. Venkatesulu, Xiaolin Li, Ramesh Tailor, John S. Bomalaski, Sunil Krishnan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12): 2381–2393.
https://doi.org/10.1158/1535-7163.MCT-18-0708
Published: 02 December 2019
View article titled, Exploiting Arginine Auxotrophy with Pegylated Arginine Deiminase (ADI-PEG20) to Sensitize Pancreatic Cancer to Radiotherapy via Metabolic Dysregulation
Open the PDF for Exploiting Arginine Auxotrophy with Pegylated Arginine Deiminase (ADI-PEG20) to Sensitize Pancreatic Cancer to Radiotherapy via Metabolic Dysregulation in another window
Includes: Supplementary data
Journal Articles

Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells

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Joshua J. Souchek, Amanda L. Davis, Tanner K. Hill, Megan B. Holmes, Bowen Qi, Pankaj K. Singh, Steven J. Kridel, Aaron M. Mohs
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (9): 1819–1830.
https://doi.org/10.1158/1535-7163.MCT-17-0013
Published: 04 September 2017
View article titled, Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells
Open the PDF for Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells in another window
Includes: Supplementary data