1-7 of 7
Pablo Avilés
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Unveiling the Mechanism of Lurbinectedin’s Action and Its Potential in Combination Therapies in Small Cell Lung Cancer

Antonio Calles, Emiliano Calvo, Gema Santamaría Nuñez, Federico Costanzo, María José Guillén, Marta Martinez Diez, Aparna Gupta, Carmen Cuevas, Jean-Marc Egly, Pablo Avilés
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF12.
https://doi.org/10.1158/1535-7163.MCT-24-0050
Published: 30 December 2024
View article titled, Unveiling the Mechanism of Lurbinectedin’s Action and Its Potential in Combination Therapies in Small Cell Lung Cancer
Open the PDF for Unveiling the Mechanism of Lurbinectedin’s Action and Its Potential in Combination Therapies in Small Cell Lung Cancer in another window
Journal Articles

MI130004, a Novel Antibody–Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding In Vivo Activity against HER2-Expressing Tumors

Pablo Avilés, Juan Manuel Domínguez, María José Guillén, María José Muñoz-Alonso, Cristina Mateo, Raquel Rodriguez-Acebes, José Manuel Molina-Guijarro, Andrés Francesch, Juan Fernando Martínez-Leal, Simon Munt, Carlos M. Galmarini, Carmen Cuevas
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (4): 786–794.
https://doi.org/10.1158/1535-7163.MCT-17-0795
Published: 01 April 2018
View article titled, MI130004, a Novel Antibody–Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding <em>In Vivo</em> Activity against HER2-Expressing Tumors
Open the PDF for MI130004, a Novel Antibody–Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding <em>In Vivo</em> Activity against HER2-Expressing Tumors in another window
Includes: Supplementary data
Journal Articles

Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells

Gema Santamaría Nuñez, Carlos Mario Genes Robles, Christophe Giraudon, Juan Fernando Martínez-Leal, Emmanuel Compe, Frédéric Coin, Pablo Aviles, Carlos María Galmarini, Jean-Marc Egly
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2016) 15 (10): 2399–2412.
https://doi.org/10.1158/1535-7163.MCT-16-0172
Published: 02 October 2016
View article titled, Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells
Open the PDF for Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract A147: MI130004, a new ADC with a payload of marine origin shows outstanding activity against HER2-expressing tumors

Pablo Aviles, Maria Jose Guillen, Juan Manuel Dominguez, Carlos M. Galmarini, Carmen Cuevas
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A147.
https://doi.org/10.1158/1535-7163.TARG-15-A147
Published: 01 December 2015
View article titled, Abstract A147: MI130004, a new ADC with a payload of marine origin shows outstanding activity against HER2-expressing tumors
Journal Articles

Evaluation of antitumor efficacy of Plitidepsin in vitro in 72 patient derived tumor xenografts using a clonogenic assay and determination of a predictive gene signature

Armin Maier, Andre Korrat, Heinz Fiebig, Doreen LePage, Maria Jose Guillen, Carmen Cuevas, Pablo Aviles
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): C61.
Published: 01 November 2007
View article titled, Evaluation of antitumor efficacy of Plitidepsin <em>in vitro </em>in 72 patient derived tumor xenografts using a clonogenic assay and determination of a predictive gene signature
Journal Articles

Antitumor activity of Zalypsis® (PM00104) in experimental models of bladder, gastric and liver cancer.

Doreen LePage, Halina Sasak, Maria Jose Guillen, Wendy Grant, Carmen Cuevas, Pablo Aviles
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): C62.
Published: 01 November 2007
View article titled, Antitumor activity of Zalypsis<sup>®</sup> (PM00104) in experimental models of bladder, gastric and liver cancer.
Journal Articles

Preclinical evaluation of PM00104 to support the selection of tumor indications for clinical development

Thomas Greiner, Armin Maier, Niko Bausch, Heinz Fiebig, Doreen LePage, Maria Jose Guillen, Carmen Cuevas, Pablo Aviles
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): C60.
Published: 01 November 2007
View article titled, Preclinical evaluation of PM00104 to support the selection of tumor indications for clinical development