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Nick Loizos
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Journal Articles

Abstract C129: Antitumor efficacy and non-clinical safety of the high affinity anti-FGFR4 antibody H4: Implications for targeting the FGF19-FGFR4 axis in oncology

Timothy R. Mack, Colleen Burns Burns, Xuemei Guo, William John Feaver, Marie Prewett, Jennifer Gruber, Amelie Forest, Armando R. Irizarry, Ruslan Novosiadly, Nick Loizos, Andrew Dropsey
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): C129.
https://doi.org/10.1158/1535-7163.TARG-15-C129
Published: 01 December 2015
View article titled, Abstract C129: Antitumor efficacy and non-clinical safety of the high affinity anti-FGFR4 antibody H4: Implications for targeting the FGF19-FGFR4 axis in oncology
Journal Articles

Abstract C159: A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth.

Maria Lebron, Laura Brennan, Chris Damoci, Marie Prewett, Marina Starodubtseva, Michael Amatulli, Yiwei Zhang, Douglas Burtrum, Paul Balderes, Kris Persaud, David Surguladze, Nick Loizos, Keren Paz, Helen Kotanides
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): C159.
https://doi.org/10.1158/1535-7163.TARG-13-C159
Published: 01 November 2013
View article titled, Abstract C159: A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth.
Journal Articles

Stromal Platelet-Derived Growth Factor Receptor α (PDGFRα) Provides a Therapeutic Target Independent of Tumor Cell PDGFRα Expression in Lung Cancer Xenografts

David E. Gerber, Puja Gupta, Michael T. Dellinger, Jason E. Toombs, Michael Peyton, Inga Duignan, Jennifer Malaby, Timothy Bailey, Colleen Burns, Rolf A. Brekken, Nick Loizos
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (11): 2473–2482.
https://doi.org/10.1158/1535-7163.MCT-12-0431
Published: 08 November 2012
View article titled, Stromal Platelet-Derived Growth Factor Receptor α (PDGFRα) Provides a Therapeutic Target Independent of Tumor Cell PDGFRα Expression in Lung Cancer Xenografts
Open the PDF for Stromal Platelet-Derived Growth Factor Receptor α (PDGFRα) Provides a Therapeutic Target Independent of Tumor Cell PDGFRα Expression in Lung Cancer Xenografts in another window
Includes: Supplementary data
Journal Articles

Abstract C54: In vitro and in vivo anti-tumor activity of the antimacrophage stimulating 1-receptor antibody IMC-RON8 in breast and bladder cancer models.

Nick Loizos, Timothy Bailey, Michael Topper, Scott Eastman, Anthony Pennello, Jennifer O'Toole
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): C54.
https://doi.org/10.1158/1535-7163.TARG-11-C54
Published: 12 November 2011
View article titled, Abstract C54: In vitro and in vivo anti-tumor activity of the antimacrophage stimulating 1-receptor antibody IMC-RON8 in breast and bladder cancer models.
Journal Articles

Platelet-derived growth factor receptor-α: a novel therapeutic target in human hepatocellular cancer

Peggy Stock, Dulabh Monga, Xinping Tan, Amanda Micsenyi, Nick Loizos, Satdarshan P.S. Monga
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (7): 1932–1941.
https://doi.org/10.1158/1535-7163.MCT-06-0720
Published: 09 July 2007
View article titled, Platelet-derived growth factor receptor-α: a novel therapeutic target in human hepatocellular cancer
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Journal Articles

Targeting the platelet-derived growth factor receptor α with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: Implications as a potential therapeutic target

Nick Loizos, Yan Xu, Jim Huber, Meilin Liu, Dan Lu, Bridget Finnerty, Robin Rolser, Asra Malikzay, Anita Persaud, Erik Corcoran, Dhanvanthri S. Deevi, Paul Balderes, Rajiv Bassi, Xenia Jimenez, Christopher J. Joynes, Venkata R.M. Mangalampalli, Philipp Steiner, James R. Tonra, Yan Wu, Daniel S. Pereira, Zhenping Zhu, Dale L. Ludwig, Daniel J. Hicklin, Peter Bohlen, Larry Witte, Paul Kussie
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (3): 369–379.
https://doi.org/10.1158/1535-7163.MCT-04-0114
Published: 14 March 2005
View article titled, Targeting the platelet-derived growth factor receptor α with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: Implications as a potential therapeutic target
Open the PDF for Targeting the platelet-derived growth factor receptor α with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: Implications as a potential therapeutic target in another window