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Journal Articles

Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors

Open Access
Sakshi Tomar, Jingli Zhang, Manakamana Khanal, Jessica Hong, Abhilash Venugopalan, Qun Jiang, Manjistha Sengupta, Markku Miettinen, Nan Li, Ira Pastan, Mitchell Ho, Raffit Hassan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (7): 1195–1206.
https://doi.org/10.1158/1535-7163.MCT-22-0073
Published: 05 July 2022
View articletitled, Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors
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Includes: Supplementary data
Journal Articles

GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling

Available to Purchase
Jiajia Pan, Nan Li, Alex Renn, Hu Zhu, Lu Chen, Min Shen, Matthew D. Hall, Min Qian, Ira Pastan, Mitchell Ho
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (6): 960–973.
https://doi.org/10.1158/1535-7163.MCT-21-0778
Published: 01 June 2022
View articletitled, GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling
Open the PDF for GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling in another window
Includes: Supplementary data
Journal Articles

International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer

Open Access
Gilles Vassal, Peter J. Houghton, Stefan M. Pfister, Malcolm A. Smith, Huib N. Caron, Xiao-Nan Li, David J. Shields, Olaf Witt, Jan J. Molenaar, Sara Colombetti, Julia Schüler, Lou F. Stancato
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (8): 1462–1468.
https://doi.org/10.1158/1535-7163.MCT-20-0394
Published: 01 August 2021
View articletitled, International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer
Open the PDF for International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract LB-B12: Pediatric Preclinical Testing Consortium evaluation of 4’-thio-2’-deoxycytidine (TdCyd) and 5-aza-4’-thio-2’-deoxycytidine (Aza-TdCyd)

Free
Beverly A. Teicher, Richard B. Lock, Jerry M. Collins, Richard Gorlick, E. Anders Kolb, Peter J. Houghton, Raushan T. Kurmasheva, Xiao-Nan Li, Stephen W. Erickson, Yuelong Guo, Kathryn Evans, Lin Qi, Malcolm A. Smith
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): LB-B12.
https://doi.org/10.1158/1535-7163.TARG-17-LB-B12
Published: 01 January 2018
View articletitled, Abstract LB-B12: Pediatric Preclinical Testing Consortium evaluation of 4’-thio-2’-deoxycytidine (TdCyd) and 5-aza-4’-thio-2’-deoxycytidine (Aza-TdCyd)
Journal Articles

Abstract LB-B13: Pediatric Preclinical Testing Consortium evaluation of the CHK1 inhibitor prexasertib

Free
Kristina A. Cole, Peter J. Houghton, Raushan T. Kurmasheva, Richard Gorlick, E. Anders Kolb, Min Kang, C. Patrick Reynolds, Xiao-Nan Li, Holly Lindsay, Stephen W. Erickson, Yuelong Guo, Beverly A. Teicher, Malcolm A. Smith, John M. Maris
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): LB-B13.
https://doi.org/10.1158/1535-7163.TARG-17-LB-B13
Published: 01 January 2018
View articletitled, Abstract LB-B13: Pediatric Preclinical Testing Consortium evaluation of the CHK1 inhibitor prexasertib
Journal Articles

Radiotherapy Followed by Aurora Kinase Inhibition Targets Tumor-Propagating Cells in Human Glioblastoma

Free
Nan Li, Dustin J. Maly, Yvan H. Chanthery, Daniel W. Sirkis, Jean L. Nakamura, Mitchel S. Berger, C. David James, Kevan M. Shokat, William A. Weiss, Anders I. Persson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (2): 419–428.
https://doi.org/10.1158/1535-7163.MCT-14-0526
Published: 09 February 2015
View articletitled, Radiotherapy Followed by Aurora Kinase Inhibition Targets Tumor-Propagating Cells in Human Glioblastoma
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Includes: Supplementary data
Journal Articles

Abstract C182: Phosphodiesterase 10: A novel cancer target.

Free
Nan Li, Kevin Lee, Yaguang Xi, Bing Zhu, Bernard D. Gary, Veronica Ramirez-Alcantara, Evrim Gurpinar, Joshua Canzoneri, Alexandra Fajardo, Sara Sigler, John T. Piazza, Xi Chen, Joel Andrews, Meagan Thomas, Wenyan Lu, Yonghe Li, Danuel J. Laan, Mary P. Moyer, Suzanne Russo, Brian T. Eberhardt, Larry Yet, Adam B. Keeton, William E. Grizzle, Gary A. Piazza
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): C182.
https://doi.org/10.1158/1535-7163.TARG-13-C182
Published: 01 November 2013
View articletitled, Abstract C182: Phosphodiesterase 10: A novel cancer target.
Journal Articles

Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling

Free
Nan Li, Yaguang Xi, Heather N. Tinsley, Evrim Gurpinar, Bernard D. Gary, Bing Zhu, Yonghe Li, Xi Chen, Adam B. Keeton, Ashraf H. Abadi, Mary P. Moyer, William E. Grizzle, Wen-Chi Chang, Margie L. Clapper, Gary A. Piazza
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (9): 1848–1859.
https://doi.org/10.1158/1535-7163.MCT-13-0048
Published: 05 September 2013
View articletitled, Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling
Open the PDF for Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling in another window
Journal Articles

A Novel Sulindac Derivative Inhibits Lung Adenocarcinoma Cell Growth through Suppression of Akt/mTOR Signaling and Induction of Autophagy

Free
Evrim Gurpinar, William E. Grizzle, John J. Shacka, Burton J. Mader, Nan Li, Nicholas A. Piazza, Suzanne Russo, Adam B. Keeton, Gary A. Piazza
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5): 663–674.
https://doi.org/10.1158/1535-7163.MCT-12-0785
Published: 08 May 2013
View articletitled, A Novel Sulindac Derivative Inhibits Lung Adenocarcinoma Cell Growth through Suppression of Akt/mTOR Signaling and Induction of Autophagy
Open the PDF for A Novel Sulindac Derivative Inhibits Lung Adenocarcinoma Cell Growth through Suppression of Akt/mTOR Signaling and Induction of Autophagy in another window
Journal Articles

Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, and CMYC

Free
Xiao-Nan Li, Qin Shu, Jack Men-Feng Su, Laszlo Perlaky, Susan M. Blaney, Ching C. Lau
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (12): 1912–1922.
https://doi.org/10.1158/1535-7163.MCT-05-0184
Published: 22 December 2005
View articletitled, Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, and CMYC
Open the PDF for Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, and CMYC in another window