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Nagaraj S. Nagathihalli
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Journal Articles

Targeting Tumor–Stromal IL6/STAT3 Signaling through IL1 Receptor Inhibition in Pancreatic Cancer

Austin R. Dosch, Samara Singh, Xizi Dai, Siddharth Mehra, Iago De Castro Silva, Anna Bianchi, Supriya Srinivasan, Zhen Gao, Yuguang Ban, Xi Chen, Sulagna Banerjee, Nagaraj S. Nagathihalli, Jashodeep Datta, Nipun B. Merchant
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (11): 2280–2290.
https://doi.org/10.1158/1535-7163.MCT-21-0083
Published: 01 November 2021
View article titled, Targeting Tumor–Stromal IL6/STAT3 Signaling through IL1 Receptor Inhibition in Pancreatic Cancer
Open the PDF for Targeting Tumor–Stromal IL6/STAT3 Signaling through IL1 Receptor Inhibition in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma

Brent A. Willobee, Alexander A. Gaidarski, Austin R. Dosch, Jason A. Castellanos, Xizi Dai, Siddharth Mehra, Fanuel Messaggio, Supriya Srinivasan, Michael N. VanSaun, Nagaraj S. Nagathihalli, Nipun B. Merchant
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (7): 1246–1256.
https://doi.org/10.1158/1535-7163.MCT-19-1043
Published: 01 July 2021
View article titled, Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma
Open the PDF for Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer

Tulasigeri M. Totiger, Supriya Srinivasan, Venkatakrishna R. Jala, Purushottam Lamichhane, Austin R. Dosch, Alexander A. Gaidarski, III, Chandrashekhar Joshi, Shobith Rangappa, Jason Castellanos, Praveen Kumar Vemula, Xi Chen, Deukwoo Kwon, Nilesh Kashikar, Michael VanSaun, Nipun B. Merchant, Nagaraj S. Nagathihalli
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (2): 301–311.
https://doi.org/10.1158/1535-7163.MCT-18-0464
Published: 04 February 2019
View article titled, Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer
Open the PDF for Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Smoking Induces Epithelial-to-Mesenchymal Transition in Non–Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin

Nagaraj S. Nagathihalli, Pierre P. Massion, Adriana L. Gonzalez, Pengcheng Lu, Pran K. Datta
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (11): 2362–2372.
https://doi.org/10.1158/1535-7163.MCT-12-0107
Published: 08 November 2012
View article titled, Smoking Induces Epithelial-to-Mesenchymal Transition in Non–Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin
Open the PDF for Smoking Induces Epithelial-to-Mesenchymal Transition in Non–Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin in another window
Includes: Supplementary data