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Mitchell Ho
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Journal Articles

Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors

Open Access
Sakshi Tomar, Jingli Zhang, Manakamana Khanal, Jessica Hong, Abhilash Venugopalan, Qun Jiang, Manjistha Sengupta, Markku Miettinen, Nan Li, Ira Pastan, Mitchell Ho, Raffit Hassan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (7): 1195–1206.
https://doi.org/10.1158/1535-7163.MCT-22-0073
Published: 05 July 2022
View articletitled, Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors
Open the PDF for Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors in another window
Includes: Supplementary data
Journal Articles

GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling

Available to Purchase
Jiajia Pan, Nan Li, Alex Renn, Hu Zhu, Lu Chen, Min Shen, Matthew D. Hall, Min Qian, Ira Pastan, Mitchell Ho
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (6): 960–973.
https://doi.org/10.1158/1535-7163.MCT-21-0778
Published: 01 June 2022
View articletitled, GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling
Open the PDF for GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling in another window
Includes: Supplementary data
Journal Articles

Combination Therapy of Hepatocellular Carcinoma by GPC3-Targeted Bispecific Antibody and Irinotecan is Potent in Suppressing Tumor Growth in Mice

Available to Purchase
Xin Chen, Yanmin Chen, Rong Liang, Lanxin Xiang, Jingwen Li, Yuankui Zhu, Huixia He, Le Huang, Dianbao Zuo, Weihang Li, Xinjun Liang, Shuang Dong, Sheng Hu, Mitchell Ho, Mingqian Feng
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (1): 149–158.
https://doi.org/10.1158/1535-7163.MCT-20-1025
Published: 07 January 2022
View articletitled, Combination Therapy of Hepatocellular Carcinoma by GPC3-Targeted Bispecific Antibody and Irinotecan is Potent in Suppressing Tumor Growth in Mice
Open the PDF for Combination Therapy of Hepatocellular Carcinoma by GPC3-Targeted Bispecific Antibody and Irinotecan is Potent in Suppressing Tumor Growth in Mice in another window
Journal Articles

T-Cell Receptor Mimic Antibodies for Cancer Immunotherapy

Available to Purchase
Zhijian Duan, Mitchell Ho
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (9): 1533–1541.
https://doi.org/10.1158/1535-7163.MCT-21-0115
Published: 01 September 2021
View articletitled, T-Cell Receptor Mimic Antibodies for Cancer Immunotherapy
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Journal Articles

Abstract CN07-02: Immunotoxins targeting GPC3 for liver cancer

Free
Mitchell Ho, Bryan D Fleming, Tim F Greten, Ira Pastan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): CN07-02.
https://doi.org/10.1158/1535-7163.TARG-19-CN07-02
Published: 01 December 2019
View articletitled, Abstract CN07-02: Immunotoxins targeting GPC3 for liver cancer
Journal Articles

A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface

Available to Purchase
Zhewei Tang, Mingqian Feng, Wei Gao, Yen Phung, Weizao Chen, Amit Chaudhary, Brad St. Croix, Min Qian, Dimiter S. Dimitrov, Mitchell Ho
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (4): 416–426.
https://doi.org/10.1158/1535-7163.MCT-12-0731
Published: 08 April 2013
View articletitled, A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface
Open the PDF for A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface in another window
Includes: Supplementary data
Journal Articles

A novel human monoclonal antibody that binds with high affinity to mesothelin-expressing cells and kills them by antibody-dependent cell-mediated cytotoxicity

Available to Purchase
Yang Feng, Xiaodong Xiao, Zhongyu Zhu, Emily Streaker, Mitchell Ho, Ira Pastan, Dimiter S. Dimitrov
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (5): 1113–1118.
https://doi.org/10.1158/1535-7163.MCT-08-0945
Published: 13 May 2009
View articletitled, A novel human monoclonal antibody that binds with high affinity to mesothelin-expressing cells and kills them by antibody-dependent cell-mediated cytotoxicity
Open the PDF for A novel human monoclonal antibody that binds with high affinity to mesothelin-expressing cells and kills them by antibody-dependent cell-mediated cytotoxicity in another window