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Misako Nagasaka
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Journal Articles

Abstract LB_A17: Trial in progress: First-in-human phase I dose-escalation study of a novel Bicycle toxin conjugate (BT5528) targeting EphA2 in patients with advanced solid tumors

Elisa Fontana, Babar Bashir, Judy S. Wang, Raid Aljumaily, Jean-Pascal Machiels, Maria Vieito, Gerald Falchook, Louise Carter, Bernard Doger de Spéville, Alastair Greystoke, Sang Wun Kim, Nuria Kotecki, Alexander I. Spira, Irene Moreno Candilejo, Bristi Basu, Hans Prenen, Alberto Bessudo, Misako Nagasaka, Jordi Rodón Ahnert, Joo-Hwan Park, Min-Yuen Teo, Julia Rotow, Jie Liu, Assunta De Rienzo, Mengyao Li, Adriana Domingo, Hanna Orr, Gavin Bennett, Rajiv Sharma, Meredith McKean
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): LB_A17.
https://doi.org/10.1158/1535-7163.TARG-23-LB_A17
Published: 01 December 2023
View article titled, Abstract LB_A17: Trial in progress: First-in-human phase I dose-escalation study of a novel Bicycle toxin conjugate (BT5528) targeting EphA2 in patients with advanced solid tumors
Journal Articles

Abstract PR003: Repotrectinib in patients with ROS1 fusion-positive (ROS1+) non-small cell lung cancer (NSCLC): Update from the pivotal phase 1/2 TRIDENT-1 trial

Jessica J Lin, Byoung Chul Cho, D. Ross Camidge, Sang-We Kim, Benjamin Solomon, Rafal Dziadziuszko, Benjamin Besse, Koichi Goto, Adrianus Johannes de Langen, Jürgen Wolf, Ki Hyeong Lee, Sanjay Popat, Christoph Springfeld, Misako Nagasaka, Enriqueta Felip, Nong Yang, Shun Lu, Steven Kao, Vamsidhar Velcheti, Parneet Cheema, Shanna Stopatschinskaja, Minal Mehta, Denise Trone, Felipe Ades, Christophe Y. Calvet, Alexander Drilon
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): PR003.
https://doi.org/10.1158/1535-7163.TARG-23-PR003
Published: 01 December 2023
View article titled, Abstract PR003: Repotrectinib in patients with <em>ROS1</em> fusion-positive (<em>ROS1</em>+) non-small cell lung cancer (NSCLC): Update from the pivotal phase 1/2 TRIDENT-1 trial
Journal Articles

Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers

Husain Yar Khan, Misako Nagasaka, Amro Aboukameel, Osama Alkhalili, Md. Hafiz Uddin, Sahar F. Bannoura, Yousef Mzannar, Ibrahim Azar, Eliza W. Beal, Miguel E. Tobon, Steve H. Kim, Rafic Beydoun, Erkan Baloglu, William Senapedis, Bassel F. El-Rayes, Philip A. Philip, Ramzi M. Mohammad, Anthony F. Shields, Mohammed Najeeb Al Hallak, Asfar S. Azmi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12): 1422–1433.
https://doi.org/10.1158/1535-7163.MCT-23-0251
Published: 01 December 2023
View article titled, Anticancer Efficacy of KRAS<sup>G12C</sup> Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of <em>KRAS</em><sup>G12C</sup>-Mutant Pancreatic and Lung Cancers
Open the PDF for Anticancer Efficacy of KRAS<sup>G12C</sup> Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of <em>KRAS</em><sup>G12C</sup>-Mutant Pancreatic and Lung Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract C025: Trial in progress: First-in-human study of BBT-207 in advanced non-small cell lung cancer harboring EGFR mutation after treatment with EGFR TKI

NaEun Jeon, Alexander Spira, Douglas Orr, Lyudmila Bazhenova, Misako Nagasaka, Jin Seok Ahn, Dong-Wan Kim, Yu Jung Kim, Jimin Cho, Agnes Jung, Eunsoo Jung, Chul-Won Kim, Taiguang Jin, Yong-Hee Lee, Sang-Yoon Lee
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): C025.
https://doi.org/10.1158/1535-7163.TARG-23-C025
Published: 01 December 2023
View article titled, Abstract C025: Trial in progress: First-in-human study of BBT-207 in advanced non-small cell lung cancer harboring <em>EGFR</em> mutation after treatment with EGFR TKI
Journal Articles

Characterization of KRAS Mutation Subtypes in Non–small Cell Lung Cancer

Julia Judd, Nagla Abdel Karim, Hina Khan, Abdul Rafeh Naqash, Yasmine Baca, Joanne Xiu, Ari M. VanderWalde, Hirva Mamdani, Luis E. Raez, Misako Nagasaka, Sachin Gopalkrishna Pai, Mark A. Socinski, Jorge J. Nieva, Chul Kim, Antoinette J. Wozniak, Chukwuemeka Ikpeazu, Gilberto de Lima Lopes, Jr, Alexander I. Spira, W. Michael Korn, Edward S. Kim, Stephen V. Liu, Hossein Borghaei
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12): 2577–2584.
https://doi.org/10.1158/1535-7163.MCT-21-0201
Published: 01 December 2021
View article titled, Characterization of KRAS Mutation Subtypes in Non–small Cell Lung Cancer
Open the PDF for Characterization of KRAS Mutation Subtypes in Non–small Cell Lung Cancer in another window
Includes: Supplementary data