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Michele F. Mayo
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Journal Articles

KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors

Yogesh K. Chutake, Michele F. Mayo, Nancy Dumont, Jessica Filiatrault, Susanne B. Breitkopf, Patricia Cho, Dapeng Chen, Vaishali S. Dixit, William R. Proctor, Eric W. Kuhn, Sarah Bollinger Martinez, Alice A. McDonald, Jianfeng Qi, Kan-Nian Hu, Rahul Karnik, Joseph D. Growney, Kirti Sharma, Stefanie S. Schalm, Ashwin M. Gollerkeri, Nello Mainolfi, Juliet A. Williams, Matthew M. Weiss
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF14.
https://doi.org/10.1158/1535-7163.MCT-24-0306
Published: 03 January 2025
View article titled, KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors
Open the PDF for KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors in another window
Includes: Supplementary data
Journal Articles

A New Class of Antibody–Drug Conjugates with Potent DNA Alkylating Activity

Michael L. Miller, Nathan E. Fishkin, Wei Li, Kathleen R. Whiteman, Yelena Kovtun, Emily E. Reid, Katie E. Archer, Erin K. Maloney, Charlene A. Audette, Michele F. Mayo, Alan Wilhelm, Holly A. Modafferi, Rajeeva Singh, Jan Pinkas, Victor Goldmacher, John M. Lambert, Ravi V.J. Chari
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2016) 15 (8): 1870–1878.
https://doi.org/10.1158/1535-7163.MCT-16-0184
Published: 03 August 2016
View article titled, A New Class of Antibody–Drug Conjugates with Potent DNA Alkylating Activity
Open the PDF for A New Class of Antibody–Drug Conjugates with Potent DNA Alkylating Activity in another window
Includes: Supplementary data
Journal Articles

Abstract A221: Novel PARP6 inhibitors demonstrate in vivo efficacy in xenograft models.

Michele F. Mayo, Shaun Grosskurth, Xin Wang, Philip Petteruti, Prasad Nadella, Corinne Reimer, Keith Mikule
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A221.
https://doi.org/10.1158/1535-7163.TARG-13-A221
Published: 01 November 2013
View article titled, Abstract A221: Novel PARP6 inhibitors demonstrate <em>in vivo</em> efficacy in xenograft models.