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Michael Kragh
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Journal Articles

HER-Family Ligands Promote Acquired Resistance to Trastuzumab in Gastric Cancer

Aïda Sampera, Francisco Javier Sánchez-Martín, Oriol Arpí, Laura Visa, Mar Iglesias, Sílvia Menéndez, Élisabeth Gaye, Alba Dalmases, Sergi Clavé, Mariona Gelabert-Baldrich, Thomas Tuxen Poulsen, Michael Kragh, Beatriz Bellosillo, Joan Albanell, Ana Rovira, Clara Montagut
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (11): 2135–2145.
https://doi.org/10.1158/1535-7163.MCT-19-0455
Published: 01 November 2019
View article titled, HER-Family Ligands Promote Acquired Resistance to Trastuzumab in Gastric Cancer
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Includes: Supplementary data
Journal Articles

Acquired Resistance to a MET Antibody In Vivo Can Be Overcome by the MET Antibody Mixture Sym015

Sofie Ellebaek Pollmann, Valerie S. Calvert, Shruti Rao, Simina M. Boca, Subha Madhavan, Ivan D. Horak, Andreas Kjaer, Emanuel F. Petricoin, Michael Kragh, Thomas Tuxen Poulsen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (6): 1259–1270.
https://doi.org/10.1158/1535-7163.MCT-17-0787
Published: 31 May 2018
View article titled, Acquired Resistance to a MET Antibody <em>In Vivo</em> Can Be Overcome by the MET Antibody Mixture Sym015
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Includes: Supplementary data
Journal Articles

Simultaneous Targeting of Two Distinct Epitopes on MET Effectively Inhibits MET- and HGF-Driven Tumor Growth by Multiple Mechanisms

Michael M. Grandal, Serhiy Havrylov, Thomas T. Poulsen, Klaus Koefoed, Anna Dahlman, Gunther R. Galler, Paolo Conrotto, Sara Collins, Karsten W. Eriksen, Dafna Kaufman, George F.Vande Woude, Helle J. Jacobsen, Ivan D. Horak, Michael Kragh, Johan Lantto, Thomas Bouquin, Morag Park, Mikkel W. Pedersen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (12): 2780–2791.
https://doi.org/10.1158/1535-7163.MCT-17-0374
Published: 03 December 2017
View article titled, Simultaneous Targeting of Two Distinct Epitopes on MET Effectively Inhibits MET- and HGF-Driven Tumor Growth by Multiple Mechanisms
Open the PDF for Simultaneous Targeting of Two Distinct Epitopes on MET Effectively Inhibits MET- and HGF-Driven Tumor Growth by Multiple Mechanisms in another window
Includes: Supplementary data
Journal Articles

Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab

Mari Iida, Harsh Bahrar, Toni M. Brand, Hannah E. Pearson, John P. Coan, Rachel A. Orbuch, Bailey G. Flanigan, Adam D. Swick, Prashanth J. Prabakaran, Johan Lantto, Ivan D. Horak, Michael Kragh, Ravi Salgia, Randy J. Kimple, Deric L. Wheeler
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (9): 2175–2186.
https://doi.org/10.1158/1535-7163.MCT-16-0012
Published: 01 September 2016
View article titled, Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab
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Journal Articles

Cetuximab Resistance in Squamous Carcinomas of the Upper Aerodigestive Tract Is Driven by Receptor Tyrosine Kinase Plasticity: Potential for mAb Mixtures

Ida Kjær, Trine Lindsted, Camilla Fröhlich, Jesper Velgaard Olsen, Ivan David Horak, Michael Kragh, Mikkel Wandahl Pedersen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (7): 1614–1626.
https://doi.org/10.1158/1535-7163.MCT-15-0565
Published: 05 July 2016
View article titled, Cetuximab Resistance in Squamous Carcinomas of the Upper Aerodigestive Tract Is Driven by Receptor Tyrosine Kinase Plasticity: Potential for mAb Mixtures
Open the PDF for Cetuximab Resistance in Squamous Carcinomas of the Upper Aerodigestive Tract Is Driven by Receptor Tyrosine Kinase Plasticity: Potential for mAb Mixtures in another window
Includes: Supplementary data
Journal Articles

Targeting Three Distinct HER2 Domains with a Recombinant Antibody Mixture Overcomes Trastuzumab Resistance

Mikkel W. Pedersen, Helle J. Jacobsen, Klaus Koefoed, Anna Dahlman, Ida Kjær, Thomas T. Poulsen, Per-Johan Meijer, Lars S. Nielsen, Ivan D. Horak, Johan Lantto, Michael Kragh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (3): 669–680.
https://doi.org/10.1158/1535-7163.MCT-14-0697
Published: 09 March 2015
View article titled, Targeting Three Distinct HER2 Domains with a Recombinant Antibody Mixture Overcomes Trastuzumab Resistance
Open the PDF for Targeting Three Distinct HER2 Domains with a Recombinant Antibody Mixture Overcomes Trastuzumab Resistance in another window
Includes: Supplementary data
Journal Articles

Sym004, a Novel Anti-EGFR Antibody Mixture, Augments Radiation Response in Human Lung and Head and Neck Cancers

Shyhmin Huang, Chimera R. Peet, Jarob Saker, Chunrong Li, Eric A. Armstrong, Michael Kragh, Mikkel W. Pedersen, Paul M. Harari
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (12): 2772–2781.
https://doi.org/10.1158/1535-7163.MCT-13-0587
Published: 05 December 2013
View article titled, Sym004, a Novel Anti-EGFR Antibody Mixture, Augments Radiation Response in Human Lung and Head and Neck Cancers
Open the PDF for Sym004, a Novel Anti-EGFR Antibody Mixture, Augments Radiation Response in Human Lung and Head and Neck Cancers in another window
Includes: Supplementary data