1-6 of 6
Melissa Dumble
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent

Finith Jernigan, Arthur Branstrom, John D. Baird, Liangxian Cao, Mandar Dali, Bansri Furia, Min Jung Kim, Kylie O'Keefe, Ronald Kong, Oscar L. Laskin, Joseph M. Colacino, Mark Pykett, Anna Mollin, Josephine Sheedy, Melissa Dumble, Young-Choon Moon, Richard Sheridan, Tobias Mühlethaler, Robert J. Spiegel, Andrea E. Prota, Michel O. Steinmetz, Marla Weetall
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 1846–1857.
https://doi.org/10.1158/1535-7163.MCT-20-0774
Published: 01 October 2021
View article titled, Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent
Open the PDF for Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent in another window
Journal Articles

Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer

Anindya Dey, Xunhao Xiong, Aleia Crim, Shailendra Kumar Dhar Dwivedi, Soumyajit Banerjee Mustafi, Priyabrata Mukherjee, Liangxian Cao, Nadiya Sydorenko, Ramil Baiazitov, Young-Choon Moon, Melissa Dumble, Thomas Davis, Resham Bhattacharya
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1): 39–49.
https://doi.org/10.1158/1535-7163.MCT-17-0574
Published: 01 January 2018
View article titled, Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer
Open the PDF for Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A130: Targeting BMI-1 by the novel BMI-1 inhibitor PTC596 in acute leukemia

Yuki Nishida, Aya Maeda, Liangxian Cao, Melissa Dumble, Shinya Kimura, Thomas W. Davis, Kensuke Kojima
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A130.
https://doi.org/10.1158/1535-7163.TARG-15-A130
Published: 01 December 2015
View article titled, Abstract A130: Targeting BMI-1 by the novel BMI-1 inhibitor PTC596 in acute leukemia
Journal Articles

Reduced Expression of the Androgen Receptor by Third Generation of Antisense Shows Antitumor Activity in Models of Prostate Cancer

Yixian Zhang, Stephen Castaneda, Melissa Dumble, Maoliang Wang, Mary Mileski, Zhengxing Qu, Steven Kim, Victoria Shi, Patricia Kraft, Ying Gao, Jenny Pak, Puja Sapra, Raj Bandaru, Hong Zhao, Robert L. Vessella, Ivan D. Horak, Lee M. Greenberger
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (12): 2309–2319.
https://doi.org/10.1158/1535-7163.MCT-11-0329
Published: 07 December 2011
View article titled, Reduced Expression of the Androgen Receptor by Third Generation of Antisense Shows Antitumor Activity in Models of Prostate Cancer
Open the PDF for Reduced Expression of the Androgen Receptor by Third Generation of Antisense Shows Antitumor Activity in Models of Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Bridging the Gap between Cytotoxic and Biologic Therapy with Metronomic Topotecan and Pazopanib in Ovarian Cancer

William M. Merritt, Alpa M. Nick, Amy R. Carroll, Chunhua Lu, Koji Matsuo, Melissa Dumble, Nicholas Jennings, ShuYun Zhang, Yvonne G. Lin, Whitney A. Spannuth, Aparna A. Kamat, Rebecca L. Stone, Mian M.K. Shahzad, Robert L. Coleman, Rakesh Kumar, Anil K. Sood
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (4): 985–995.
https://doi.org/10.1158/1535-7163.MCT-09-0967
Published: 07 April 2010
View article titled, Bridging the Gap between Cytotoxic and Biologic Therapy with Metronomic Topotecan and Pazopanib in Ovarian Cancer
Open the PDF for Bridging the Gap between Cytotoxic and Biologic Therapy with Metronomic Topotecan and Pazopanib in Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers

Peter Sabbatini, Susan Korenchuk, Jason L. Rowand, Arthur Groy, Qi Liu, Dominic Leperi, Charity Atkins, Melissa Dumble, Jingsong Yang, Kelly Anderson, Ryan G. Kruger, Richard R. Gontarek, Kenneth R. Maksimchuk, Sapna Suravajjala, Russell R. Lapierre, J. Brad Shotwell, Joseph W. Wilson, Stanley D. Chamberlain, Sridhar K. Rabindran, Rakesh Kumar
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (10): 2811–2820.
https://doi.org/10.1158/1535-7163.MCT-09-0423
Published: 12 October 2009
View article titled, GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers
Open the PDF for GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers in another window
Includes: Supplementary data