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Martine B.W. Prinsen
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Journal Articles

Abstract A141: Computational models of synergy contribute to efficient combination screening

Free
Joost C.M. Uitdehaag, Martine B.W. Prinsen, Derek W. van Tilborg, Jeffrey J. Kooijman, Jelle Dylus, Jeroen A.D.M. de Roos, Suzanne J.C. van Gerwen, Jos de Man, Rogier C. Buijsman, Guido J.R. Zaman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): A141.
https://doi.org/10.1158/1535-7163.TARG-19-A141
Published: 01 December 2019
View articletitled, Abstract A141: Computational models of synergy contribute to efficient combination screening
Journal Articles

Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017

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Joost C.M. Uitdehaag, Jeffrey J. Kooijman, Jeroen A.D.M. de Roos, Martine B.W. Prinsen, Jelle Dylus, Nicole Willemsen-Seegers, Yusuke Kawase, Masaaki Sawa, Jos de Man, Suzanne J.C. van Gerwen, Rogier C. Buijsman, Guido J.R. Zaman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (2): 470–481.
https://doi.org/10.1158/1535-7163.MCT-18-0877
Published: 04 February 2019
View articletitled, Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017
Open the PDF for Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017 in another window
Includes: Supplementary data
Journal Articles

Abstract B155: Combining cell panel screening with analysis of gene expression levels reveals features of drug response and resistance

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Joost C.M. Uitdehaag, Jeffrey Kooijman, Jeroen A.D.M. de Roos, Martine B.W. Prinsen, Jelle Dylus, Suzanne J.C. van Gerwen, Rogier C. Buijsman, Guido J.R. Zaman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): B155.
https://doi.org/10.1158/1535-7163.TARG-17-B155
Published: 01 January 2018
View articletitled, Abstract B155: Combining cell panel screening with analysis of gene expression levels reveals features of drug response and resistance
Journal Articles

TTK Inhibitors as a Targeted Therapy for CTNNB1 ( β -catenin) Mutant Cancers

Free
Guido J.R. Zaman, Jeroen A.D.M. de Roos, Marion A.A. Libouban, Martine B.W. Prinsen, Jos de Man, Rogier C. Buijsman, Joost C.M. Uitdehaag
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (11): 2609–2617.
https://doi.org/10.1158/1535-7163.MCT-17-0342
Published: 01 November 2017
View articletitled, TTK Inhibitors as a Targeted Therapy for CTNNB1 ( β -catenin) Mutant Cancers
Open the PDF for TTK Inhibitors as a Targeted Therapy for CTNNB1 ( β -catenin) Mutant Cancers in another window
Includes: Supplementary data
Journal Articles

Cell Panel Profiling Reveals Conserved Therapeutic Clusters and Differentiates the Mechanism of Action of Different PI3K/mTOR, Aurora Kinase and EZH2 Inhibitors

Free
Joost C.M. Uitdehaag, Jeroen A.D.M. de Roos, Martine B.W. Prinsen, Nicole Willemsen-Seegers, Judith R.F. de Vetter, Jelle Dylus, Antoon M. van Doornmalen, Jeffrey Kooijman, Masaaki Sawa, Suzanne J.C. van Gerwen, Jos de Man, Rogier C. Buijsman, Guido J.R. Zaman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (12): 3097–3109.
https://doi.org/10.1158/1535-7163.MCT-16-0403
Published: 01 December 2016
View articletitled, Cell Panel Profiling Reveals Conserved Therapeutic Clusters and Differentiates the Mechanism of Action of Different PI3K/mTOR, Aurora Kinase and EZH2 Inhibitors
Open the PDF for Cell Panel Profiling Reveals Conserved Therapeutic Clusters and Differentiates the Mechanism of Action of Different PI3K/mTOR, Aurora Kinase and EZH2 Inhibitors in another window
Includes: Supplementary data