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Marion Dorsch
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Journal Articles

Abstract B075: Identifying functional allosteric binding sites using a systematic and scalable AMPS screening platform for drug discovery

Anil K Padyana, Anna Schinzel, Gordon Murray, Joseph H LaPointe, Kaitlyn Selmer, Truc Pham, Melissa J Buskes, Shomit Sengupta, Maria-Jesus Blanco, Thomas Roddy, Marion Dorsch
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): B075.
https://doi.org/10.1158/1535-7163.TARG-23-B075
Published: 01 December 2023
View article titled, Abstract B075: Identifying functional allosteric binding sites using a systematic and scalable AMPS screening platform for drug discovery
Journal Articles

Abstract B127: Evaluating PRKACA as a therapeutic target for Fibrolamellar Carcinoma

Stefanie S Schalm, Erin O’Hearn, Kevin Wilson, Timothy LaBranche, Grace Silva, Lucian DiPietro, Neil Bifulco, Richard Woessner, Nicolas Stransky, Darshan Sappal, Adam Shutes, Robert Campbell, Riadh Lobbardi, Michael Palmer, Joseph Kim, Stephen Miller, Marion Dorsch, Christoph Lengauer, Timothy Guzi, Vivek Kadambi, Andrew Garner, Klaus P Hoeflich
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): B127.
https://doi.org/10.1158/1535-7163.TARG-19-B127
Published: 01 December 2019
View article titled, Abstract B127: Evaluating PRKACA as a therapeutic target for Fibrolamellar Carcinoma
Journal Articles

Abstract A118: Identification of resistance mechanisms to FGFR4 targeted therapy in hepatocellular carcinoma

Megan A Hatlen, Oleg Schmidt-Kittler, Cori-Ann Sherwin, Emily Rozsahegyi, Nooreen Rubin, Michael Sheets, Joseph L Kim, Chandra Miduturu, Neil Bifulco, Natasja Brooijmans, Hongliang Shi, Timothy Guzi, Andy Boral, Christoph Lengauer, Marion Dorsch, Richard D Kim, Yoon-Koo Kang, Beni B Wolf, Klaus P Hoeflich
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): A118.
https://doi.org/10.1158/1535-7163.TARG-19-A118
Published: 01 December 2019
View article titled, Abstract A118: Identification of resistance mechanisms to FGFR4 targeted therapy in hepatocellular carcinoma
Journal Articles

Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor

Sauveur-Michel Maira, Sabina Pecchi, Alan Huang, Matthew Burger, Mark Knapp, Dario Sterker, Christian Schnell, Daniel Guthy, Tobi Nagel, Marion Wiesmann, Saskia Brachmann, Christine Fritsch, Marion Dorsch, Patrick Chène, Kevin Shoemaker, Alain De Pover, Daniel Menezes, Georg Martiny-Baron, Doriano Fabbro, Christopher J. Wilson, Robert Schlegel, Francesco Hofmann, Carlos García-Echeverría, William R. Sellers, Charles F. Voliva
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (2): 317–328.
https://doi.org/10.1158/1535-7163.MCT-11-0474
Published: 08 February 2012
View article titled, Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor
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Includes: Supplementary data