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Maria R. Baer
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Journal Articles

PP2A-activating Drugs Enhance FLT3 Inhibitor Efficacy through AKT Inhibition–Dependent GSK-3β–Mediated c-Myc and Pim-1 Proteasomal Degradation

Mario Scarpa, Prerna Singh, Christopher M. Bailey, Jonelle K. Lee, Shivani Kapoor, Rena G. Lapidus, Sandrine Niyongere, Jaya Sangodkar, Yin Wang, Danilo Perrotti, Goutham Narla, Maria R. Baer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (4): 676–690.
https://doi.org/10.1158/1535-7163.MCT-20-0663
Published: 01 April 2021
View article titled, PP2A-activating Drugs Enhance FLT3 Inhibitor Efficacy through AKT Inhibition–Dependent GSK-3β–Mediated c-Myc and Pim-1 Proteasomal Degradation
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Includes: Supplementary data
Journal Articles

FLT3 Inhibitors in Acute Myeloid Leukemia: Current Status and Future Directions

Maria Larrosa-Garcia, Maria R. Baer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (6): 991–1001.
https://doi.org/10.1158/1535-7163.MCT-16-0876
Published: 01 June 2017
View article titled, FLT3 Inhibitors in Acute Myeloid Leukemia: Current Status and Future Directions
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Journal Articles

Activation of the Constitutive Androstane Receptor Increases the Therapeutic Index of CHOP in Lymphoma Treatment

William D. Hedrich, Jingwei Xiao, Scott Heyward, Yao Zhang, Junran Zhang, Maria R. Baer, Hazem E. Hassan, Hongbing Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (3): 392–401.
https://doi.org/10.1158/1535-7163.MCT-15-0667
Published: 06 March 2016
View article titled, Activation of the Constitutive Androstane Receptor Increases the Therapeutic Index of CHOP in Lymphoma Treatment
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Includes: Supplementary data
Journal Articles

The Novel BCR-ABL and FLT3 Inhibitor Ponatinib Is a Potent Inhibitor of the MDR-Associated ATP-Binding Cassette Transporter ABCG2

Rupashree Sen, Karthika Natarajan, Jasjeet Bhullar, Suneet Shukla, Hong-Bin Fang, Ling Cai, Zhe-Sheng Chen, Suresh V. Ambudkar, Maria R. Baer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (9): 2033–2044.
https://doi.org/10.1158/1535-7163.MCT-12-0302
Published: 06 September 2012
View article titled, The Novel BCR-ABL and FLT3 Inhibitor Ponatinib Is a Potent Inhibitor of the MDR-Associated ATP-Binding Cassette Transporter ABCG2
Open the PDF for The Novel BCR-ABL and FLT3 Inhibitor Ponatinib Is a Potent Inhibitor of the MDR-Associated ATP-Binding Cassette Transporter ABCG2 in another window
Journal Articles

Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL

Jinrong Cheng, Bonnie L. Hylander, Maria R. Baer, Xing Chen, Elizabeth A. Repasky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (7): 1844–1853.
https://doi.org/10.1158/1535-7163.MCT-06-0050
Published: 04 August 2006
View article titled, Multiple mechanisms underlie resistance of leukemia cells to Apo2 Ligand/TRAIL
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Journal Articles

In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells

Hans Minderman, Jeffrey M. Conroy, Kieran L. O'Loughlin, Devin McQuaid, Paul Quinn, Song Li, Lakshmi Pendyala, Norma J. Nowak, Maria R. Baer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2005) 4 (6): 885–900.
https://doi.org/10.1158/1535-7163.MCT-04-0048
Published: 14 June 2005
View article titled, <em>In vitro</em> and <em>in vivo</em> irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells
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Journal Articles

Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein

Tracy Brooks, Hans Minderman, Kieran L. O'Loughlin, Paula Pera, Iwao Ojima, Maria R. Baer, Ralph J. Bernacki
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (11): 1195–1205.
Published: 14 November 2003
View article titled, Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein
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