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Mads Daugaard
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Journal Articles

Abstract LB_C11: Small-molecule bifunctional inhibitors of PARP1/2 and HDAC enzymes

Sarah Truong, Louise Ramos, Beibei Zhai, Jay Joshi, Fariba Ghaidi, Mona Marzban, Hans Adomat, Charles Chen, John Langlands, Dennis Brown, Jeffrey Bacha, Colin Collins, Poul Sorensen, Wang Shen, Mads Daugaard
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): LB_C11.
https://doi.org/10.1158/1535-7163.TARG-23-LB_C11
Published: 01 December 2023
View article titled, Abstract LB_C11: Small-molecule bifunctional inhibitors of PARP1/2 and HDAC enzymes
Journal Articles

Abstract P081: In vitro activity and efficacy of novel dual PARP-HDAC inhibitors

Sarah Truong, Fariba Ghaidi, Louise Ramos, Jay Joshi, Dennis Brown, Neil Sankar, John Langlands, Jeffrey Bacha, Wang Shen, Mads Daugaard
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12_Supplement): P081.
https://doi.org/10.1158/1535-7163.TARG-21-P081
Published: 01 December 2021
View article titled, Abstract P081: <em>In vitro</em> activity and efficacy of novel dual PARP-HDAC inhibitors
Journal Articles

Abstract P053: VAL-083 (dianhydrogalactitol) synergizes with PARP inhibitors in BRCA-proficient and BRCA-deficient ovarian cancer models

Anne Steino, Guangan He, Beibei Zhai, Jeffrey Bacha, Dennis M. Brown, Mads Daugaard, Zahid H. Siddik
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12_Supplement): P053.
https://doi.org/10.1158/1535-7163.TARG-21-P053
Published: 01 December 2021
View article titled, Abstract P053: VAL-083 (dianhydrogalactitol) synergizes with PARP inhibitors in BRCA-proficient and BRCA-deficient ovarian cancer models
Journal Articles

Selective Inhibition of the Lactate Transporter MCT4 Reduces Growth of Invasive Bladder Cancer

Tilman Todenhöfer, Roland Seiler, Craig Stewart, Igor Moskalev, Jian Gao, Simroop Ladhar, Alireza Kamjabi, Nader Al Nakouzi, Tetsuharo Hayashi, Stephen Choi, Yuzhuo Wang, Sebastian Frees, Mads Daugaard, Htoo Zarni Oo, Pascale Fisel, Matthias Schwab, Elke Schaeffeler, James Douglas, Jörg Hennenlotter, Jens Bedke, Ewan A. Gibb, Ladan Fazli, Arnulf Stenzl, Peter C. Black
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (12): 2746–2755.
https://doi.org/10.1158/1535-7163.MCT-18-0107
Published: 03 December 2018
View article titled, Selective Inhibition of the Lactate Transporter MCT4 Reduces Growth of Invasive Bladder Cancer
Open the PDF for Selective Inhibition of the Lactate Transporter MCT4 Reduces Growth of Invasive Bladder Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A109: DNA-damaging agent dianhydrogalactitol (VAL-083) targets HR repair pathway and suggests combination therapy with topoisomerase and PARP inhibitors

Beibei Zhai, Guangan He, Anne Steino, Jeffrey A. Bacha, Dennis M. Brown, Zahid Siddik, Mads Daugaard
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): A109.
https://doi.org/10.1158/1535-7163.TARG-17-A109
Published: 01 January 2018
View article titled, Abstract A109: DNA-damaging agent dianhydrogalactitol (VAL-083) targets HR repair pathway and suggests combination therapy with topoisomerase and PARP inhibitors
Journal Articles

Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation

Nada Lallous, Eric Leblanc, Ravi S.N. Munuganti, Mohamed D.H. Hassona, Nader Al Nakouzi, Shannon Awrey, Helene Morin, Mani Roshan-Moniri, Kriti Singh, Sam Lawn, Takeshi Yamazaki, Hans H. Adomat, Christophe Andre, Mads Daugaard, Robert N. Young, Emma S. Tomlinson Guns, Paul S. Rennie, Artem Cherkasov
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (12): 2936–2945.
https://doi.org/10.1158/1535-7163.MCT-16-0354
Published: 01 December 2016
View article titled, Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation
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Journal Articles

BAMLET Activates a Lysosomal Cell Death Program in Cancer Cells

Paul Rammer, Line Groth-Pedersen, Thomas Kirkegaard, Mads Daugaard, Anna Rytter, Piotr Szyniarowski, Maria Høyer-Hansen, Lou Klitgaard Povlsen, Jesper Nylandsted, Jakob E. Larsen, Marja Jäättelä
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (1): 24–32.
https://doi.org/10.1158/1535-7163.MCT-09-0559
Published: 12 January 2010
View article titled, BAMLET Activates a Lysosomal Cell Death Program in Cancer Cells
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