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Lyubomir T. Vassilev
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Journal Articles

Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors

Audrey Turchick, Astrid Zimmermann, Li-Ya Chiu, Heike Dahmen, Brian Elenbaas, Frank T. Zenke, Andree Blaukat, Lyubomir T. Vassilev
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (7): 859–872.
https://doi.org/10.1158/1535-7163.MCT-22-0685
Published: 05 July 2023
View article titled, Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors
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Includes: Supplementary data
Journal Articles

A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies

Astrid Zimmermann, Frank T. Zenke, Li-Ya Chiu, Heike Dahmen, Ulrich Pehl, Thomas Fuchss, Thomas Grombacher, Beatrix Blume, Lyubomir T. Vassilev, Andree Blaukat
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (6): 859–870.
https://doi.org/10.1158/1535-7163.MCT-21-0934
Published: 01 June 2022
View article titled, A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies
Open the PDF for A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies in another window
Includes: Supplementary data
Journal Articles

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

Frank T. Zenke, Astrid Zimmermann, Christian Sirrenberg, Heike Dahmen, Vladimir Kirkin, Ulrich Pehl, Thomas Grombacher, Claudia Wilm, Thomas Fuchss, Christiane Amendt, Lyubomir T. Vassilev, Andree Blaukat
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2020) 19 (5): 1091–1101.
https://doi.org/10.1158/1535-7163.MCT-19-0734
Published: 04 May 2020
View article titled, Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models
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Includes: Supplementary data
Journal Articles

Abstract C128: Small-molecule antagonists of MDM2 and MDMX.

Thelma Thompson, Bradford Graves, Mingxuan Xia, Cheryl Janson, Christine Lukacs, Dayanand Deo, Kuo-Sen Huang, Christian Tovar, Allen Lovey, Jutta Wanner, Lyubomir T. Vassilev
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): C128.
https://doi.org/10.1158/1535-7163.TARG-11-C128
Published: 12 November 2011
View article titled, Abstract C128: Small-molecule antagonists of MDM2 and MDMX.
Journal Articles

1,25-Dihydroxyvitamin D3 Enhances the Apoptotic Activity of MDM2 Antagonist Nutlin-3a in Acute Myeloid Leukemia Cells Expressing Wild-type p53

Thelma Thompson, Michael Andreeff, George P. Studzinski, Lyubomir T. Vassilev
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (5): 1158–1168.
https://doi.org/10.1158/1535-7163.MCT-09-1036
Published: 09 May 2010
View article titled, 1,25-Dihydroxyvitamin D<sub>3</sub> Enhances the Apoptotic Activity of MDM2 Antagonist Nutlin-3a in Acute Myeloid Leukemia Cells Expressing Wild-type p53
Open the PDF for 1,25-Dihydroxyvitamin D<sub>3</sub> Enhances the Apoptotic Activity of MDM2 Antagonist Nutlin-3a in Acute Myeloid Leukemia Cells Expressing Wild-type p53 in another window
Includes: Supplementary data
Journal Articles

Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53

Harm C.A. Graat, Jan E. Carette, Frederik H.E. Schagen, Lyubomir T. Vassilev, Winald R. Gerritsen, Gertjan J.L. Kaspers, Paul I.J.M. Wuisman, Victor W. van Beusechem
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (5): 1552–1561.
https://doi.org/10.1158/1535-7163.MCT-06-0631
Published: 18 May 2007
View article titled, Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53
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Journal Articles

Macrophage inhibitory cytokine-1: A novel biomarker for p53 pathway activation

Hong Yang, Zoran Filipovic, David Brown, Samuel N. Breit, Lyubomir T. Vassilev
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (10): 1023–1029.
Published: 24 October 2003
View article titled, Macrophage inhibitory cytokine-1: A novel biomarker for p53 pathway activation
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