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Lisa Maria Mustachio
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Journal Articles

A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers

Masanori Kawakami, Lisa Maria Mustachio, Yulong Chen, Zibo Chen, Xiuxia Liu, Cheng-Hsin Wei, Jason Roszik, Adam S. Kittai, Alexey V. Danilov, Xiaoshan Zhang, Bingliang Fang, Jing Wang, John V. Heymach, Liliya Tyutyunyk-Massey, Sarah J. Freemantle, Jonathan M. Kurie, Xi Liu, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2021) 20 (3): 477–489.
https://doi.org/10.1158/1535-7163.MCT-19-0987
Published: 02 March 2021
View articletitled, A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers
Open the PDF for A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers in another window
Includes: Supplementary data
Journal Articles

Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy

Lin Zheng, Zibo Chen, Masanori Kawakami, Yulong Chen, Jason Roszik, Lisa Maria Mustachio, Jonathan M. Kurie, Pamela Villalobos, Wei Lu, Carmen Behrens, Barbara Mino, Luisa M. Solis, Jennifer Silvester, Kelsie L. Thu, David W Cescon, Jaime Rodriguez-Canales, Ignacio I. Wistuba, Tak W. Mak, Xi Liu, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (10): 1775–1786.
https://doi.org/10.1158/1535-7163.MCT-18-0864
Published: 01 October 2019
View articletitled, Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy
Open the PDF for Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy in another window
Includes: Supplementary data
Journal Articles

Engaging Anaphase Catastrophe Mechanisms to Eradicate Aneuploid Cancers

Masanori Kawakami, Lisa Maria Mustachio, Xi Liu, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (4): 724–731.
https://doi.org/10.1158/1535-7163.MCT-17-1108
Published: 01 April 2018
View articletitled, Engaging Anaphase Catastrophe Mechanisms to Eradicate Aneuploid Cancers
Open the PDF for Engaging Anaphase Catastrophe Mechanisms to Eradicate Aneuploid Cancers in another window
Journal Articles

Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2

Alexey V. Danilov, Shanhu Hu, Bernardo Orr, Kristina Godek, Lisa Maria Mustachio, David Sekula, Xi Liu, Masanori Kawakami, Faye M. Johnson, Duane A. Compton, Sarah J. Freemantle, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (11): 2758–2766.
https://doi.org/10.1158/1535-7163.MCT-16-0127
Published: 01 November 2016
View articletitled, Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2
Open the PDF for Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2 in another window
Includes: Multimedia, Supplementary data
Journal Articles

Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown

Shanhu Hu, Yun Lu, Bernardo Orr, Kristina Godek, Lisa Maria Mustachio, Masanori Kawakami, David Sekula, Duane A. Compton, Sarah Freemantle, Ethan Dmitrovsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (11): 2576–2585.
https://doi.org/10.1158/1535-7163.MCT-15-0443
Published: 03 November 2015
View articletitled, Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown
Open the PDF for Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown in another window
Includes: Supplementary data