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Journal Articles

A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis

Qian Wang, Shengnan Jia, Ding Wang, Xuyang Chen, Dhan V. Kalvakolanu, Hongwu Zheng, Xiaodong Wei, Naiyan Wen, Hang Liang, Baofeng Guo, Ling Zhang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (12): 2542–2553.
https://doi.org/10.1158/1535-7163.MCT-20-0037
Published: 02 December 2020
View article titled, A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis
Open the PDF for A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis in another window
Includes: Supplementary data
Journal Articles

The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors

Govindi J. Samaranayake, Clara I. Troccoli, Ling Zhang, Mai Huynh, Christina J. Jayaraj, Debin Ji, Lisa McPherson, Yoshiyuki Onishi, Dao M. Nguyen, David J. Robbins, Mahsa Karbaschi, Marcus S. Cooke, Antonio Barrientos, Eric T. Kool, Priyamvada Rai
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (2): 432–446.
https://doi.org/10.1158/1535-7163.MCT-19-0437
Published: 06 February 2020
View article titled, The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors
Open the PDF for The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors in another window
Includes: Supplementary data
Journal Articles

Abstract A080: A phase 1 study of single-agent pexidartinib in Asian patients with advanced solid tumors (NCT02734433)

Chia-Chi Lin, Jih-Hsiang Lee, Chih-Hung Hsu, Wei-Wu Chen, Yu-Hsin Yen, Chih-Hsin Yang, Ling Zhang, Shun-ichi Sasaki, Lillian Chiu, Ann-Lii Cheng
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): A080.
https://doi.org/10.1158/1535-7163.TARG-17-A080
Published: 01 January 2018
View article titled, Abstract A080: A phase 1 study of single-agent pexidartinib in Asian patients with advanced solid tumors (NCT02734433)
Journal Articles

Rho Kinase Inhibitor Fasudil Suppresses the Vasculogenic Mimicry of B16 Mouse Melanoma Cells Both In Vitro and In Vivo

Yun Xia, Xian-Yi Cai, Ji-Quan Fan, Li-Ling Zhang, Jing-Hua Ren, Jing Chen, Zhen-Yu Li, Rui-Guang Zhang, Fang Zhu, Gang Wu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (7): 1582–1590.
https://doi.org/10.1158/1535-7163.MCT-14-0523
Published: 06 July 2015
View article titled, Rho Kinase Inhibitor Fasudil Suppresses the Vasculogenic Mimicry of B16 Mouse Melanoma Cells Both <em>In Vitro</em> and <em>In Vivo</em>
Open the PDF for Rho Kinase Inhibitor Fasudil Suppresses the Vasculogenic Mimicry of B16 Mouse Melanoma Cells Both <em>In Vitro</em> and <em>In Vivo</em> in another window
Includes: Supplementary data
Journal Articles

A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter

Daniel Hochhauser, Rob Glynne-Jones, Vanessa Potter, Cristina Grávalos, Thomas J. Doyle, Kumudu Pathiraja, Qing Zhang, Ling Zhang, Edward A. Sausville
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5): 809–818.
https://doi.org/10.1158/1535-7163.MCT-12-0710
Published: 08 May 2013
View article titled, A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the <em>O</em><sup>6</sup>-Methylguanine-DNA Methyltransferase Promoter
Open the PDF for A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the <em>O</em><sup>6</sup>-Methylguanine-DNA Methyltransferase Promoter in another window