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Lili Liu
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Journal Articles

Abstract A104: Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: Overriding the limit with methoxyamine (TRC102) to inhibit base excision repair.

Alina Bulgar, Lachelle D. Weeks, Yanling Miao, Shuming Yang, Yan Xu, Chunguang Guo, Sanford Markowitz, Stanton L. Gerson, Lili Liu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): A104.
https://doi.org/10.1158/1535-7163.TARG-11-A104
Published: 12 November 2011
View article titled, Abstract A104: Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: Overriding the limit with methoxyamine (TRC102) to inhibit base excision repair.
Journal Articles

Abstract A100: Pemetrexed-induced uracil accumulation is an importatn source of DNA damage in UNG deficient cells, contributing to hematologic toxicity.

Lachelle D. Weeks, Gabriel Zetner, Peter Scacheri, Lili Liu, Stanton L. Gerson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): A100.
https://doi.org/10.1158/1535-7163.TARG-11-A100
Published: 12 November 2011
View article titled, Abstract A100: Pemetrexed-induced uracil accumulation is an importatn source of DNA damage in UNG deficient cells, contributing to hematologic toxicity.
Journal Articles

Tyrosine Phosphatase Inhibitor-3 Sensitizes Melanoma and Colon Cancer to Biotherapeutics and Chemotherapeutics

Suman Kundu, Keke Fan, Mingli Cao, Daniel J. Lindner, Ralph Tuthill, Lili Liu, Stanton Gerson, Ernest Borden, Taolin Yi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (8): 2287–2296.
https://doi.org/10.1158/1535-7163.MCT-10-0159
Published: 09 August 2010
View article titled, Tyrosine Phosphatase Inhibitor-3 Sensitizes Melanoma and Colon Cancer to Biotherapeutics and Chemotherapeutics
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Journal Articles

Abstract B62: A phase 1 study of oral TRC102 (methoxyamine), an inhibitor of base‐excision repair, to potentiate the therapeutic effects of pemetrexed in patients with advanced refractory cancer

Michael S. Gordon, Glen J. Weiss, Lee S. Rosen, David S. Mendelson, Ramesh K. Ramanathan, Jonathan Goldman, Bonne J. Adams, Delia Alvarez, Lili Liu, Stanton L. Gerson, Charles P. Theuer, Bryan R. Leigh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B62.
https://doi.org/10.1158/1535-7163.TARG-09-B62
Published: 10 December 2009
View article titled, Abstract B62: A phase 1 study of oral TRC102 (methoxyamine), an inhibitor of base‐excision repair, to potentiate the therapeutic effects of pemetrexed in patients with advanced refractory cancer
Journal Articles

Prevention of base excision repair by TRC102 (methoxyamine) potentiates the antitumor activity of pemetrexed in vitro and in vivo.

Lili Liu, Alina Bulgar, Jon Donze, Bonne Adams, Charles Theuer, Stanton Gerson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A292.
Published: 01 November 2007
View article titled, Prevention of base excision repair by TRC102 (methoxyamine) potentiates the antitumor activity of pemetrexed<em> in vitro and in vivo.</em>
Journal Articles

Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts

Lili Liu, Ling Yan, Jon R. Donze, Stanton L. Gerson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (10): 1061–1066.
Published: 24 October 2003
View article titled, Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts
Open the PDF for Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts in another window