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Journal Articles

Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent

Finith Jernigan, Arthur Branstrom, John D. Baird, Liangxian Cao, Mandar Dali, Bansri Furia, Min Jung Kim, Kylie O'Keefe, Ronald Kong, Oscar L. Laskin, Joseph M. Colacino, Mark Pykett, Anna Mollin, Josephine Sheedy, Melissa Dumble, Young-Choon Moon, Richard Sheridan, Tobias Mühlethaler, Robert J. Spiegel, Andrea E. Prota, Michel O. Steinmetz, Marla Weetall
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 1846–1857.
https://doi.org/10.1158/1535-7163.MCT-20-0774
Published: 01 October 2021
View article titled, Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent
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Journal Articles

Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties

Liangxian Cao, Marla Weetall, Christopher Trotta, Katherine Cintron, Jiyuan Ma, Min Jung Kim, Bansri Furia, Charles Romfo, Jason D. Graci, Wencheng Li, Joshua Du, Josephine Sheedy, Jean Hedrick, Nicole Risher, Shirley Yeh, Hongyan Qi, Tamil Arasu, Seongwoo Hwang, William Lennox, Ronald Kong, Janet Petruska, Young-Choon Moon, John Babiak, Thomas W. Davis, Allan Jacobson, Neil G. Almstead, Art Branstrom, Joseph M. Colacino, Stuart W. Peltz
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2019) 18 (1): 3–16.
https://doi.org/10.1158/1535-7163.MCT-18-0863
Published: 02 January 2019
View article titled, Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
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Includes: Supplementary data
Journal Articles

Inhibition of BMI1, a Therapeutic Approach in Endometrial Cancer

Megan Buechel, Anindya Dey, Shailendra Kumar Dhar Dwivedi, Aleia Crim, Kai Ding, Roy Zhang, Priyabrata Mukherjee, Kathleen N. Moore, Liangxian Cao, Arthur Branstrom, Marla Weetall, John Baird, Resham Bhattacharya
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (10): 2136–2143.
https://doi.org/10.1158/1535-7163.MCT-17-1192
Published: 01 October 2018
View article titled, Inhibition of BMI1, a Therapeutic Approach in Endometrial Cancer
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Includes: Supplementary data
Journal Articles

Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer

Anindya Dey, Xunhao Xiong, Aleia Crim, Shailendra Kumar Dhar Dwivedi, Soumyajit Banerjee Mustafi, Priyabrata Mukherjee, Liangxian Cao, Nadiya Sydorenko, Ramil Baiazitov, Young-Choon Moon, Melissa Dumble, Thomas Davis, Resham Bhattacharya
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1): 39–49.
https://doi.org/10.1158/1535-7163.MCT-17-0574
Published: 01 January 2018
View article titled, Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Abstract A130: Targeting BMI-1 by the novel BMI-1 inhibitor PTC596 in acute leukemia

Yuki Nishida, Aya Maeda, Liangxian Cao, Melissa Dumble, Shinya Kimura, Thomas W. Davis, Kensuke Kojima
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A130.
https://doi.org/10.1158/1535-7163.TARG-15-A130
Published: 01 December 2015
View article titled, Abstract A130: Targeting BMI-1 by the novel BMI-1 inhibitor PTC596 in acute leukemia