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Kevan M. Shokat
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Journal Articles

CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization

Lisa Werr, Dennis Plenker, Marcel A. Dammert, Carina Lorenz, Johannes Brägelmann, Hannah L. Tumbrink, Sebastian Klein, Anna Schmitt, Reinhard Büttner, Thorsten Persigehl, Kevan M. Shokat, F. Thomas Wunderlich, Alison M. Schram, Martin Peifer, Martin L. Sos, H. Christian Reinhardt, Roman K. Thomas
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (5): 821–830.
DOI: https://doi.org/10.1158/1535-7163.MCT-21-0820
Published: 04 May 2022
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Includes: Supplementary data
Journal Articles

A Patient-derived Xenograft Model of Pancreatic Neuroendocrine Tumors Identifies Sapanisertib as a Possible New Treatment for Everolimus-resistant Tumors

Chester E. Chamberlain, Michael S. German, Katherine Yang, Jason Wang, Henry VanBrocklin, Melanie Regan, Kevan M. Shokat, Gregory S. Ducker, Grace E. Kim, Byron Hann, David B. Donner, Robert S. Warren, Alan P. Venook, Emily K. Bergsland, Danny Lee, Yucheng Wang, Eric K. Nakakura
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (12): 2702–2709.
DOI: https://doi.org/10.1158/1535-7163.MCT-17-1204
Published: 03 December 2018
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Includes: Supplementary data
Journal Articles

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib

Rowan E. Miller, Rachel Brough, Ilirjana Bajrami, Chris T. Williamson, Simon McDade, James Campbell, Asha Kigozi, Rumana Rafiq, Helen Pemberton, Rachel Natrajan, Josephine Joel, Holly Astley, Claire Mahoney, Jonathan D. Moore, Chris Torrance, John D. Gordan, James T. Webber, Rebecca S. Levin, Kevan M. Shokat, Sourav Bandyopadhyay, Christopher J. Lord, Alan Ashworth
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (7): 1472–1484.
DOI: https://doi.org/10.1158/1535-7163.MCT-15-0554
Published: 05 July 2016
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Includes: Supplementary data
Journal Articles

Abstract PR01: Inhibitory role of phosphatidylinositol-3,4-bisphosphate in triple-negative breast cancers

Darien E. Reed, Kevan M. Shokat
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (7_Supplement): PR01.
DOI: https://doi.org/10.1158/1538-8514.PI3K14-PR01
Published: 06 July 2015
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Journal Articles

Radiotherapy Followed by Aurora Kinase Inhibition Targets Tumor-Propagating Cells in Human Glioblastoma

Nan Li, Dustin J. Maly, Yvan H. Chanthery, Daniel W. Sirkis, Jean L. Nakamura, Mitchel S. Berger, C. David James, Kevan M. Shokat, William A. Weiss, Anders I. Persson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (2): 419–428.
DOI: https://doi.org/10.1158/1535-7163.MCT-14-0526
Published: 09 February 2015
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Includes: Supplementary data
Journal Articles

Abstract PR15: Primary resistance to MAPK inhibition in BRAF-mutant cancer is determined by kinetics of feedback release

Martin L. Sos, John D. Gordan, Kevan M. Shokat
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5_Supplement): PR15.
DOI: https://doi.org/10.1158/1535-7163.PMS-PR15
Published: 01 May 2014
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Journal Articles

Abstract PL04-03: Selective inhibition of K-Ras G12C through allosteric control of GTP affinity and effector interactions.

Jonathan M. Ostrem, Ulf Peters, Martin L. Sos, James A. Wells, Kevan M. Shokat
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): PL04-03.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-PL04-03
Published: 01 November 2013
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Journal Articles

Abstract A180: Selective inhibition of K-Ras G12C through allosteric control of GTP affinity and effector interactions.

Ulf Peters, Jonathan M. Ostrem, Martin L. Sos, James A. Wells, Kevan M. Shokat
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A180.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-A180
Published: 01 November 2013
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Journal Articles

Characterization of structurally distinct, isoform-selective phosphoinositide 3′-kinase inhibitors in combination with radiation in the treatment of glioblastoma

Jack S. Chen, Linda J. Zhou, Michal Entin-Meer, Xiaodong Yang, Mila Donker, Zachary A. Knight, William Weiss, Kevan M. Shokat, Daphne Haas-Kogan, David Stokoe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (4): 841–850.
DOI: https://doi.org/10.1158/1535-7163.MCT-07-0393
Published: 15 April 2008
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Journal Articles

Effect of combined DNA repair inhibition and G2 checkpoint inhibition on cell cycle progression after DNA damage

Christopher M. Sturgeon, Zachary A. Knight, Kevan M. Shokat, Michel Roberge
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (4): 885–892.
DOI: https://doi.org/10.1158/1535-7163.MCT-05-0358
Published: 28 April 2006
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