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Ker Yu
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Journal Articles

Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function

Rui Jin, Liang Liu, Yun Xing, Tao Meng, Lanping Ma, Jinpeng Pei, Ying Cong, Xuesai Zhang, Zhiqiang Ren, Xin Wang, Jingkang Shen, Ker Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (11): 2340–2352.
https://doi.org/10.1158/1535-7163.MCT-20-0076
Published: 03 November 2020
View article titled, Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
Open the PDF for Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function in another window
Includes: Supplementary data
Journal Articles

Abstract B145: Highly selective pyrazolopyrimidine mTOR inhibitors with profound in vivo antitumor activity

Arie Zask, Joshua Kaplan, Kevin Curran, Jeroen C. Verheijen, David J. Richard, Natasja Brooijmans, Eric Bennett, Judy Lucas, Lourdes Toral‐Barza, Irwin Hollander, James J. Gibbons, Robert T. Abraham, Semiramis Ayral‐Kaloustian, Tarek S. Mansour, Ker Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B145.
https://doi.org/10.1158/1535-7163.TARG-09-B145
Published: 10 December 2009
View article titled, Abstract B145: Highly selective pyrazolopyrimidine mTOR inhibitors with profound <em>in vivo</em> antitumor activity
Journal Articles

Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines

Lourdes Toral-Barza, Wei-Guo Zhang, Xinyi Huang, Leonard A. McDonald, Edward J. Salaski, Laurel R. Barbieri, Wei-Dong Ding, Girija Krishnamurthy, Yong Bo Hu, Judy Lucas, Valerie S. Bernan, Ping Cai, Jeremy I. Levin, Tarek S. Mansour, James J. Gibbons, Robert T. Abraham, Ker Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11): 3028–3038.
https://doi.org/10.1158/1535-7163.MCT-07-0211
Published: 19 November 2007
View article titled, Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines
Open the PDF for Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines in another window