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Juliet Williams
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Journal Articles

Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers

Free
Huai-Xiang Hao, Hongyun Wang, Chen Liu, Steven Kovats, Roberto Velazquez, Hengyu Lu, Bhavesh Pant, Matthew Shirley, Matthew J. Meyer, Minying Pu, Joanne Lim, Michael Fleming, LeighAnn Alexander, Ali Farsidjani, Matthew J. LaMarche, Susan Moody, Serena J. Silver, Giordano Caponigro, Darrin D. Stuart, Tinya J. Abrams, Peter S. Hammerman, Juliet Williams, Jeffrey A. Engelman, Silvia Goldoni, Morvarid Mohseni
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12): 2368–2380.
https://doi.org/10.1158/1535-7163.MCT-19-0170
Published: 02 December 2019
View article titled, Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers
Open the PDF for Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract C028: Discovery and characterization of next generation monoclonal antibodies targeting the inhibitory Fc gamma receptor CD32b for the treatment of B and plasma cell malignancies

Free
Haihui Lu, Dongshu Chen, Sunyoung Jang, Babette Wolf, Stefan Ewert, Meghan Flaherty, Fangmin Xu, Sinan Isim, Yeonjiu Shim, Christina Dornelas, Nicole Balke, Xavier Charles Leber, Meike Scharenberg, Johanna Koelln, Eugene Choi, Rebecca Ward, Jennifer Johnson, Thomas Calzascia, Isabelle Isnardi, Juliet Williams, Heather Huet, Emma Lees, Matthew J Meyer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C028.
https://doi.org/10.1158/1535-7163.TARG-19-C028
Published: 01 December 2019
View article titled, Abstract C028: Discovery and characterization of next generation monoclonal antibodies targeting the inhibitory Fc gamma receptor CD32b for the treatment of B and plasma cell malignancies
Journal Articles

Abstract A145: SHP2 inhibition restores sensitivity to ALK inhibitors in resistant ALK-rearranged NSCLC

Free
Leila Dardaei, Hui Qin Wang, Manrose Singh, Paul Fordjour, Satoshi Yoda, Grainne Kerr, Jinsheng Liang, Yichen Cao, Yan Chen, Justin Gainor, Luc Friboulet, Ibiayi Dagogo-Jack, David Myers, Emma Labrot, David Ruddy, Melissa Parks, Dana Lee, Richard DiCecca, Susan Moody, Huaixiang Hao, Morvarid Mohseni, Matthew LaMarche, Juliet Williams, Keith Hoffmaster, Giordano Caponigro, Alice Shaw, Aaron Hata, Cyril Benes, Fang Li, Jeffrey Engelman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): A145.
https://doi.org/10.1158/1535-7163.TARG-17-A145
Published: 01 January 2018
View article titled, Abstract A145: SHP2 inhibition restores sensitivity to ALK inhibitors in resistant ALK-rearranged NSCLC
Journal Articles

Abstract A11: Modeling drug response and resistance using patient-derived xenograft models.

Free
Guizhi Yang, John Green, Colleen Kowal, Shawn Cogan, Roberto Velazquez, John Monahan, Joshua Korn, Nicholas Keen, Juliet Williams, Hui Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A11.
https://doi.org/10.1158/1535-7163.TARG-13-A11
Published: 01 November 2013
View article titled, Abstract A11: Modeling drug response and resistance using patient-derived xenograft models.
Journal Articles

Abstract C210: LIM kinase small molecule inhibitors block tumor cell invasion

Free
Diane Crighton, Mark Charles, Elizabeth Trivier, Steven Hooper, Rebecca Scott, Michelle Riddick, Joanna Brookfield, Tennyson Ekwuru, Martin Stockley, Caroline Foxton, Juliet Williams, Tony Raynham, Erik Sahai, Michael Olson, Tim Hammonds
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): C210.
https://doi.org/10.1158/1535-7163.TARG-09-C210
Published: 10 December 2009
View article titled, Abstract C210: LIM kinase small molecule inhibitors block tumor cell invasion
Journal Articles

Abstract B261: A novel small molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vivo

Free
Christopher R. Ireson, Stephen Jamieson, Stephen Stribbling, Rachel Sutherland, Tony Raynham, Juliet Williams, Mark Charles, Azadeh Bagherzadeh, Muddasar Farooq, Kuzhuvelil B. Harikumar, Ajaikumar B. Kunnumakkara, Amit Deorukhkar, Zhimin Tong, Dipen Maru, Parmeswaran Diagaradjane, Yoichi Matsuo, Sunul Krishnan, Juri Gelovani, Bharat Aggarwal, Sushovan Guha
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B261.
https://doi.org/10.1158/1535-7163.TARG-09-B261
Published: 10 December 2009
View article titled, Abstract B261: A novel small molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vivo