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    Joseph D. Growney
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    Journal Articles

    KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors

    Yogesh K. Chutake, Michele F. Mayo, Nancy Dumont, Jessica Filiatrault, Susanne B. Breitkopf, Patricia Cho, Dapeng Chen, Vaishali S. Dixit, William R. Proctor, Eric W. Kuhn, Sarah Bollinger Martinez, Alice A. McDonald, Jianfeng Qi, Kan-Nian Hu, Rahul Karnik, Joseph D. Growney, Kirti Sharma, Stefanie S. Schalm, Ashwin M. Gollerkeri, Nello Mainolfi, Juliet A. Williams, Matthew M. Weiss
    Journal: Molecular Cancer Therapeutics
    Mol Cancer Ther OF1–OF14.
    https://doi.org/10.1158/1535-7163.MCT-24-0306
    Published: 03 January 2025
    Abstract
    View article titled, KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors
    Open the PDF for KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors in another window
    Includes: Supplementary data

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