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Jon C. Aster
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Journal Articles

p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition

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Felix Oppel, Senyao Shao, Sarah Gendreizig, Mark W. Zimmerman, Matthias Schürmann, Viyof Ful Flavian, Peter Goon, Susan N. Chi, Jon C. Aster, Holger Sudhoff, A. Thomas Look
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (11): 1689–1700.
https://doi.org/10.1158/1535-7163.MCT-21-0770
Published: 03 November 2022
View articletitled, p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition
Open the PDF for p53 Pathway Inactivation Drives SMARCB1-deficient p53-wildtype Epithelioid Sarcoma Onset Indicating Therapeutic Vulnerability Through MDM2 Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract PL07-03: The multifaceted role of Notch signaling in tumor/microenvironment interaction

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Jon C. Aster
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): PL07-03.
https://doi.org/10.1158/1535-7163.TARG-15-PL07-03
Published: 01 December 2015
View articletitled, Abstract PL07-03: The multifaceted role of Notch signaling in tumor/microenvironment interaction
Journal Articles

Abstract B39: MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma

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Erica M. Walsh, Adlai R. Grayson, Michael J. Cameron, Jernej Godec, Todd Ashworth, Alexandra B. Aserlind, Hongfang Wang, Gerard Evan, Michael J. Kluk, James E. Bradner, Jon C. Aster, Christopher A. French
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5_Supplement): B39.
https://doi.org/10.1158/1535-7163.PMS-B39
Published: 01 May 2014
View articletitled, Abstract B39: MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma
Journal Articles

Abstract B249: Small molecule inhibitors of the Pim protein kinases block the growth of T‐acute lymphoblastic leukemias

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Andrew S. Kraft, Ying‐Wei Lin, Zanna Beharry, Elizabeth G. Hill, Jin H. Song, Wenxue Wang, Zuping Xia, Zhenhua Zhang, Peter D. Aplan, Jon C. Aster, Charles D. Smith
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B249.
https://doi.org/10.1158/1535-7163.TARG-09-B249
Published: 10 December 2009
View articletitled, Abstract B249: Small molecule inhibitors of the Pim protein kinases block the growth of T‐acute lymphoblastic leukemias