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John A. Copland
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Journal Articles

Patient-Derived Tumor Xenograft Study with CDK4/6 Inhibitor Plus AKT Inhibitor for the Management of Metastatic Castration-Resistant Prostate Cancer

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Adam M. Kase, Justyna Gleba, James L. Miller, Erin Miller, Joachim Petit, Michael T. Barrett, Yumei Zhou, Ephraim E. Parent, Hancheng Cai, Joshua A. Knight, Jacob Orme, Jordan Reynolds, William F. Durham, Thomas M. Metz, Nathalie Meurice, Brandy Edenfield, Aylin Alasonyalilar Demirer, Ahmet Bilgili, Peyton G. Hickman, Matthew L. Pawlush, Laura Marlow, Daniel P. Wickland, Winston Tan, John A. Copland, III
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (6): 823–835.
https://doi.org/10.1158/1535-7163.MCT-23-0296
Published: 04 June 2024
View articletitled, Patient-Derived Tumor Xenograft Study with CDK4/6 Inhibitor Plus AKT Inhibitor for the Management of Metastatic Castration-Resistant Prostate Cancer
Open the PDF for Patient-Derived Tumor Xenograft Study with CDK4/6 Inhibitor Plus AKT Inhibitor for the Management of Metastatic Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site

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Ryan P. Mackay, Paul M. Weinberger, John A. Copland, Elahe Mahdavian, Qinqin Xu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (6): 925–935.
https://doi.org/10.1158/1535-7163.MCT-21-0619
Published: 01 June 2022
View articletitled, YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site
Open the PDF for YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site in another window
Includes: Supplementary data
Journal Articles

Molecular Inhibitor of QSOX1 Suppresses Tumor Growth In Vivo

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Amber L. Fifield, Paul D. Hanavan, Douglas O. Faigel, Eduard Sergienko, Andrey Bobkov, Nathalie Meurice, Joachim L. Petit, Alysia Polito, Thomas R. Caulfield, Erik P. Castle, John A. Copland, Debabrata Mukhopadhyay, Krishnendu Pal, Shamit K. Dutta, Huijun Luo, Thai H. Ho, Douglas F. Lake
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (1): 112–122.
https://doi.org/10.1158/1535-7163.MCT-19-0233
Published: 03 January 2020
View articletitled, Molecular Inhibitor of QSOX1 Suppresses Tumor Growth In Vivo
Open the PDF for Molecular Inhibitor of QSOX1 Suppresses Tumor Growth In Vivo in another window
Includes: Supplementary data
Journal Articles

Reexpression of Tumor Suppressor, sFRP1, Leads to Antitumor Synergy of Combined HDAC and Methyltransferase Inhibitors in Chemoresistant Cancers

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Simon J. Cooper, Christina A. von Roemeling, Kylie H. Kang, Laura A. Marlow, Stefan K. Grebe, Michael E. Menefee, Han W. Tun, Gerardo Colon-Otero, Edith A. Perez, John A. Copland
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (10): 2105–2115.
https://doi.org/10.1158/1535-7163.MCT-11-0873
Published: 09 October 2012
View articletitled, Reexpression of Tumor Suppressor, sFRP1, Leads to Antitumor Synergy of Combined HDAC and Methyltransferase Inhibitors in Chemoresistant Cancers
Open the PDF for Reexpression of Tumor Suppressor, sFRP1, Leads to Antitumor Synergy of Combined HDAC and Methyltransferase Inhibitors in Chemoresistant Cancers in another window
Includes: Supplementary data