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Journal Articles

Abstract A42: Palbociclib potentiates nab-paclitaxel efficacy in pancreatic ductal adenocarcinoma

Manuel Hidalgo, Camino Menendez, Jing Yuan, Beatriz Salvador, Tao Xie, John Chionis, Pedro Lopez-Casas, Xianxian Zheng, James Hardwick, Paul Rejto, Peter Olson, Todd VanArsdale, David J. Shields
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A42.
https://doi.org/10.1158/1535-7163.TARG-15-A42
Published: 01 December 2015
View article titled, Abstract A42: Palbociclib potentiates nab-paclitaxel efficacy in pancreatic ductal adenocarcinoma
Journal Articles

Inhibition of Wild-Type p53-Expressing AML by the Novel Small Molecule HDM2 Inhibitor CGM097

Ellen Weisberg, Ensar Halilovic, Vesselina G. Cooke, Atsushi Nonami, Tao Ren, Takaomi Sanda, Irene Simkin, Jing Yuan, Brandon Antonakos, Louise Barys, Moriko Ito, Richard Stone, Ilene Galinsky, Kristen Cowens, Erik Nelson, Martin Sattler, Sebastien Jeay, Jens U. Wuerthner, Sean M. McDonough, Marion Wiesmann, James D. Griffin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (10): 2249–2259.
https://doi.org/10.1158/1535-7163.MCT-15-0429
Published: 05 October 2015
View article titled, Inhibition of Wild-Type p53-Expressing AML by the Novel Small Molecule HDM2 Inhibitor CGM097
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Includes: Supplementary data
Journal Articles

Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871)

Adam Pavlicek, Maruja E. Lira, Nathan V. Lee, Keith A. Ching, Jingjing Ye, Joan Cao, Scott J. Garza, Kenneth E. Hook, Mark Ozeck, Stephanie T. Shi, Jing Yuan, Xianxian Zheng, Paul A. Rejto, Julie L.C. Kan, James G. Christensen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (12): 2929–2939.
https://doi.org/10.1158/1535-7163.MCT-13-0442-T
Published: 05 December 2013
View article titled, Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871)
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Includes: Supplementary data
Journal Articles

Abstract C149: The PKC inhibitor Sotrastaurin selectively inhibits the growth of GNAQ mutant uveal melanoma.

Rosemary Barrett, Ribo Guo, Jing Yuan, Vesselina Cooke, Anthony Vattay, Joshua Korn, Guiqing Liang, Xin Li, Ramu Thiruvamoor, Andrew Wylie, Anka Bric, Nicholas Keen, William Sellers
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): C149.
https://doi.org/10.1158/1535-7163.TARG-13-C149
Published: 01 November 2013
View article titled, Abstract C149: The PKC inhibitor Sotrastaurin selectively inhibits the growth of GNAQ mutant uveal melanoma.
Journal Articles

Colorectal Cancer Cells Refractory to Anti-VEGF Treatment Are Vulnerable to Glycolytic Blockade due to Persistent Impairment of Mitochondria

Jie Xu, Jilin Wang, Bin Xu, Haiyan Ge, Xiaolin Zhou, Jing-Yuan Fang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5): 717–724.
https://doi.org/10.1158/1535-7163.MCT-12-1016-T
Published: 08 May 2013
View article titled, Colorectal Cancer Cells Refractory to Anti-VEGF Treatment Are Vulnerable to Glycolytic Blockade due to Persistent Impairment of Mitochondria
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Journal Articles

An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735

Kenneth E. Hook, Scott J. Garza, Maruja E. Lira, Keith A. Ching, Nathan V. Lee, Joan Cao, Jing Yuan, Jingjing Ye, Mark Ozeck, Stephanie T. Shi, Xianxian Zheng, Paul A. Rejto, Julie L.C. Kan, James G. Christensen, Adam Pavlicek
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (3): 710–719.
https://doi.org/10.1158/1535-7163.MCT-11-0184
Published: 06 March 2012
View article titled, An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735
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Includes: Supplementary data
Journal Articles

Therapeutic Potential of AZD1480 for the Treatment of Human Glioblastoma

Braden C. McFarland, Jing-Yuan Ma, Catherine P. Langford, G. Yancey Gillespie, Hao Yu, Ying Zheng, Susan E. Nozell, Dennis Huszar, Etty N. Benveniste
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (12): 2384–2393.
https://doi.org/10.1158/1535-7163.MCT-11-0480
Published: 07 December 2011
View article titled, Therapeutic Potential of AZD1480 for the Treatment of Human Glioblastoma
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Includes: Supplementary data
Journal Articles

PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity

Jing Yuan, Pramod P. Mehta, Min-Jean Yin, Shaoxian Sun, Aihua Zou, Jeffrey Chen, Kristina Rafidi, Zheng Feng, Jeffrey Nickel, Jon Engebretsen, Jill Hallin, Alessandra Blasina, Eric Zhang, Leslie Nguyen, Minghao Sun, Peter K. Vogt, Aileen McHarg, Hengmiao Cheng, James G. Christensen, Julie L.C. Kan, Shubha Bagrodia
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11): 2189–2199.
https://doi.org/10.1158/1535-7163.MCT-11-0185
Published: 08 November 2011
View article titled, PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity
Open the PDF for PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity in another window
Includes: Supplementary data
Journal Articles

N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing

Hongtao Wang, Barry J. Maurer, Yong-Yu Liu, Elaine Wang, Jeremy C. Allegood, Samuel Kelly, Holly Symolon, Ying Liu, Alfred H. Merrill,, Jr., Valérie Gouazé-Andersson, Jing Yuan Yu, Armando E. Giuliano, Myles C. Cabot
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (9): 2967–2976.
https://doi.org/10.1158/1535-7163.MCT-08-0549
Published: 11 September 2008
View article titled, <em>N</em>-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing
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Journal Articles

Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity

James Turkson, Joon S. Kim, Shumin Zhang, Jing Yuan, Mei Huang, Matthew Glenn, Eric Haura, Said Sebti, Andrew D. Hamilton, Richard Jove
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (3): 261–269.
https://doi.org/10.1158/1535-7163.261.3.3
Published: 16 March 2004
View article titled, Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity
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