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Jim Nonomiya
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Journal Articles

GDC-0980 Is a Novel Class I PI3K/mTOR Kinase Inhibitor with Robust Activity in Cancer Models Driven by the PI3K Pathway

Jeffrey J. Wallin, Kyle A. Edgar, Jane Guan, Megan Berry, Wei Wei Prior, Leslie Lee, John D. Lesnick, Cristina Lewis, Jim Nonomiya, Jodie Pang, Laurent Salphati, Alan G. Olivero, Daniel P. Sutherlin, Carol O'Brien, Jill M. Spoerke, Sonal Patel, Letitia Lensun, Robert Kassees, Leanne Ross, Mark R. Lackner, Deepak Sampath, Marcia Belvin, Lori S. Friedman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (12): 2426–2436.
https://doi.org/10.1158/1535-7163.MCT-11-0446
Published: 07 December 2011
View article titled, GDC-0980 Is a Novel Class I PI3K/mTOR Kinase Inhibitor with Robust Activity in Cancer Models Driven by the PI3K Pathway
Open the PDF for GDC-0980 Is a Novel Class I PI3K/mTOR Kinase Inhibitor with Robust Activity in Cancer Models Driven by the PI3K Pathway in another window
Includes: Supplementary data
Journal Articles

Abstract C201: A novel potent and selective inhibitor of PI3K/mTOR, GDC‐0980, currently in phase I clinical trials

Lori S. Friedman, Marcia Belvin, Leanne Berry, Megan Berry, Georgette Castanedo, Kyle Edgar, Adrian Folkes, Jane Guan, Tim Heffron, John Lesnick, Cris Lewis, Jim Nonomiya, Alan Olivero, Sonal Patel, Jodie Pang, Wei Wei Prior, Laurent Salphati, Deepak Sampath, Dan Sutherlin, Jeff Wallin, Bingyan Zhu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): C201.
https://doi.org/10.1158/1535-7163.TARG-09-C201
Published: 10 December 2009
View article titled, Abstract C201: A novel potent and selective inhibitor of PI3K/mTOR, GDC‐0980, currently in phase I clinical trials
Journal Articles

Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy

Cathy Zhang, Karen Lundgren, Zhengming Yan, Maria E. Arango, Sharon Price, Andrea Huber, Joseph Higgins, Gabriel Troche, Judith Skaptason, Tatiana Koudriakova, Jim Nonomiya, Michelle Yang, Patrick O'Connor, Steve Bender, Gerrit Los, Cristina Lewis, Bart Jessen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (4): 818–828.
https://doi.org/10.1158/1535-7163.MCT-07-0440
Published: 15 April 2008
View article titled, Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy
Open the PDF for Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy in another window