Page 1 | Search Results | Molecular Cancer Therapeutics | American Association for Cancer Research

1-14 of 14

Sort by

Sort Order Select

Journal Articles

Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress

Antje Lindemann, Ameeta A. Patel, Lin Tang, Noriaki Tanaka, Frederico O. Gleber-Netto, Mason D. Bartels, Li Wang, Daniel J. McGrail, Shiaw-Yih Lin, Steven J. Frank, Mitchell J. Frederick, Jeffrey N. Myers, Abdullah A. Osman

Mol Cancer Ther (2021) 20 (7): 1257–1269.

https://doi.org/10.1158/1535-7163.MCT-20-0252

Published: 01 July 2021

View articletitled, Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress

Includes: Supplementary data

Journal Articles

Abstract A073: Gemcitabine cotreatment enhances the therapeutic effect of prexasertib in HNSCC cells that are less sensitive to Chk1 inhibition single-agent therapy

Mayur A. Gadhikar, Jeffrey N. Myers

Mol Cancer Ther (2018) 17 (1_Supplement): A073.

https://doi.org/10.1158/1535-7163.TARG-17-A073

Published: 01 January 2018

View articletitled, Abstract A073: Gemcitabine cotreatment enhances the therapeutic effect of prexasertib in HNSCC cells that are less sensitive to Chk1 inhibition single-agent therapy

Journal Articles

Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model

Vlad C. Sandulache, Yunyun Chen, Heath D. Skinner, Tongtong Lu, Lei Feng, Laurence E. Court, Jeffrey N. Myers, Raymond E. Meyn, Clifton D. Fuller, James A. Bankson, Stephen Y. Lai

Mol Cancer Ther (2015) 14 (12): 2901–2908.

https://doi.org/10.1158/1535-7163.MCT-15-0217

Published: 06 December 2015

View articletitled, Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model

Includes: Supplementary data

Journal Articles

Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-Risk TP53 Mutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence

Abdullah A. Osman, Marcus M. Monroe, Marcus V. Ortega Alves, Ameeta A. Patel, Panagiotis Katsonis, Alison L. Fitzgerald, David M. Neskey, Mitchell J. Frederick, Sang Hyeok Woo, Carlos Caulin, Teng-Kuei Hsu, Thomas O. McDonald, Marek Kimmel, Raymond E. Meyn, Olivier Lichtarge, Jeffrey N. Myers

Mol Cancer Ther (2015) 14 (2): 608–619.

https://doi.org/10.1158/1535-7163.MCT-14-0735-T

Published: 09 February 2015

View articletitled, Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-Risk TP53 Mutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence

Includes: Supplementary data

Journal Articles

A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell Carcinoma

Tuhina Mazumdar, Lauren A. Byers, Patrick Kwok Shing Ng, Gordon B. Mills, Shaohua Peng, Lixia Diao, You-Hong Fan, Katherine Stemke-Hale, John V. Heymach, Jeffrey N. Myers, Bonnie S. Glisson, Faye M. Johnson

Mol Cancer Ther (2014) 13 (11): 2738–2750.

https://doi.org/10.1158/1535-7163.MCT-13-1090

Published: 03 November 2014

View articletitled, A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell Carcinoma

Includes: Supplementary data

Journal Articles

Chk1/2 Inhibition Overcomes the Cisplatin Resistance of Head and Neck Cancer Cells Secondary to the Loss of Functional p53

Mayur A. Gadhikar, Maria Rita Sciuto, Marcus Vinicius Ortega Alves, Curtis R. Pickering, Abdullah A. Osman, David M. Neskey, Mei Zhao, Alison L. Fitzgerald, Jeffrey N. Myers, Mitchell J. Frederick

Mol Cancer Ther (2013) 12 (9): 1860–1873.

https://doi.org/10.1158/1535-7163.MCT-13-0157

Published: 05 September 2013

View articletitled, Chk1/2 Inhibition Overcomes the Cisplatin Resistance of Head and Neck Cancer Cells Secondary to the Loss of Functional p53

Includes: Supplementary data

Journal Articles

Elevated Cyclin D1 Expression Is Predictive for a Benefit from TPF Induction Chemotherapy in Oral Squamous Cell Carcinoma Patients with Advanced Nodal Disease

Lai-Ping Zhong, Dong-Wang Zhu, William N. William, Jr, Ying Liu, Jie Ma, Cheng-Zhe Yang, Xiao Yang, Li-Zhen Wang, Jiang Li, Jeffrey N. Myers, J. Jack Lee, Chen-Ping Zhang, Zhi-Yuan Zhang

Mol Cancer Ther (2013) 12 (6): 1112–1121.

https://doi.org/10.1158/1535-7163.MCT-12-1013

Published: 09 June 2013

View articletitled, Elevated Cyclin D1 Expression Is Predictive for a Benefit from TPF Induction Chemotherapy in Oral Squamous Cell Carcinoma Patients with Advanced Nodal Disease

Includes: Supplementary data

Journal Articles

Glycolytic Inhibition Alters Anaplastic Thyroid Carcinoma Tumor Metabolism and Improves Response to Conventional Chemotherapy and Radiation

Vlad C. Sandulache, Heath D. Skinner, Yuan Wang, Yunyun Chen, Cristina T. Dodge, Thomas J. Ow, James A. Bankson, Jeffrey N. Myers, Stephen Y. Lai

Mol Cancer Ther (2012) 11 (6): 1373–1380.

https://doi.org/10.1158/1535-7163.MCT-12-0041

Published: 10 June 2012

View articletitled, Glycolytic Inhibition Alters Anaplastic Thyroid Carcinoma Tumor Metabolism and Improves Response to Conventional Chemotherapy and Radiation

Includes: Supplementary data

Journal Articles

Abstract A145: EGFR-targeting of carbon nanovectors loaded with paclitaxel improves their antitumor efficacy and radiosensitization of head and neck squamous cell carcinoma in vivo.

Daisuke Sano, Jacob M. Berlin, Daniela C. Marcano, David R. Valdecanas, Ge Zhou, Luka Milas, James M. Tour, Jeffrey N. Myers

Mol Cancer Ther (2011) 10 (11_Supplement): A145.

https://doi.org/10.1158/1535-7163.TARG-11-A145

Published: 12 November 2011

View articletitled, Abstract A145: EGFR-targeting of carbon nanovectors loaded with paclitaxel improves their antitumor efficacy and radiosensitization of head and neck squamous cell carcinoma in vivo.

Journal Articles

Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

Mol Cancer Ther (2010) 9 (6): 1755–1763.

https://doi.org/10.1158/1535-7163.MCT-09-1047

Published: 09 June 2010

View articletitled, Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

Journal Articles

Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice

Seungwon Kim, Yasemin D. Yazici, Gabriel Calzada, Zhuo-Ying Wang, Maher N. Younes, Samar A. Jasser, Adel K. El-Naggar, Jeffrey N. Myers

Mol Cancer Ther (2007) 6 (6): 1785–1792.

https://doi.org/10.1158/1535-7163.MCT-06-0595

Published: 15 June 2007

View articletitled, Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice

Journal Articles

Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model

Maher N. Younes, Young Wook Park, Yasemin Dakak Yazici, Meirong Gu, Alfredo A. Santillan, Xiaolin Nong, Seungwon Kim, Samar A. Jasser, Adel K. El-Naggar, Jeffrey N. Myers

Mol Cancer Ther (2006) 5 (11): 2696–2705.

https://doi.org/10.1158/1535-7163.MCT-05-0228

Published: 22 November 2006

View articletitled, Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model

Journal Articles

Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer

Maher N. Younes, Seungwon Kim, Orhan G. Yigitbasi, Mahitosh Mandal, Samar A. Jasser, Yasemin Dakak Yazici, Bradley A. Schiff, Adel El-Naggar, Benjamin N. Bekele, Gordon B. Mills, Jeffrey N. Myers

Mol Cancer Ther (2005) 4 (8): 1146–1156.

https://doi.org/10.1158/1535-7163.MCT-05-0078

Published: 10 August 2005

View articletitled, Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer

Journal Articles

Targeted molecular therapy of anaplastic thyroid carcinoma with AEE788

Seungwon Kim, Bradley A. Schiff, Orhan G. Yigitbasi, Dao Doan, Samar A. Jasser, B. Nebiyou Bekele, Mahitosh Mandal, Jeffrey N. Myers

Mol Cancer Ther (2005) 4 (4): 632–640.

https://doi.org/10.1158/1535-7163.MCT-04-0293

Published: 12 April 2005

View articletitled, Targeted molecular therapy of anaplastic thyroid carcinoma with AEE788

Update search

NARROW

Format

Subjects

Journal

Article Type

Issue Section

Date

Availability

Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress

Abstract A073: Gemcitabine cotreatment enhances the therapeutic effect of prexasertib in HNSCC cells that are less sensitive to Chk1 inhibition single-agent therapy

Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model

Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-Risk TP53 Mutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence

A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell Carcinoma

Chk1/2 Inhibition Overcomes the Cisplatin Resistance of Head and Neck Cancer Cells Secondary to the Loss of Functional p53

Elevated Cyclin D1 Expression Is Predictive for a Benefit from TPF Induction Chemotherapy in Oral Squamous Cell Carcinoma Patients with Advanced Nodal Disease

Glycolytic Inhibition Alters Anaplastic Thyroid Carcinoma Tumor Metabolism and Improves Response to Conventional Chemotherapy and Radiation

Abstract A145: EGFR-targeting of carbon nanovectors loaded with paclitaxel improves their antitumor efficacy and radiosensitization of head and neck squamous cell carcinoma in vivo.

Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice

Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model

Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer

Targeted molecular therapy of anaplastic thyroid carcinoma with AEE788

Email alerts

AACR Journals

Update search

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only