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Jeff Settleman
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Journal Articles

Abstract B121: An oncogene-linked prodrug strategy in lung cancer

Aaron Boudreau, Jennifer Roth, James Rong, Niclas Olsson, Chris Mader, Jordan Byran, Jordan Rossen, Li Wang, Kevin Larpenteur, Amy Goodale, Colin Trepicchio, Samantha Bender, Aviad Tsherniak, Aravind Subramanian, Mustafa Kocak, Federica Piccioni, Josh Bittker, Cong Zhu, Frank Li, Nick Eriksson, Daphne Koller, Fiona McAllister, Todd Golub, Jeff Settleman, Ari Firestone, David Stokoe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): B121.
https://doi.org/10.1158/1535-7163.TARG-19-B121
Published: 01 December 2019
View article titled, Abstract B121: An oncogene-linked prodrug strategy in lung cancer
Journal Articles

Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma

Nisebita Sahu, Emily Chan, Felix Chu, Thinh Pham, Hartmut Koeppen, William Forrest, Mark Merchant, Jeff Settleman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (9): 1729–1738.
https://doi.org/10.1158/1535-7163.MCT-17-0009
Published: 04 September 2017
View article titled, Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma
Open the PDF for Cotargeting of MEK and PDGFR/STAT3 Pathways to Treat Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells

Ho-June Lee, Yi Cao, Victoria Pham, Elizabeth Blackwood, Catherine Wilson, Marie Evangelista, Christiaan Klijn, David Stokoe, Jeff Settleman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (4): 694–704.
https://doi.org/10.1158/1535-7163.MCT-16-0504
Published: 02 April 2017
View article titled, Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells
Open the PDF for Ras–MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract LB-C02: A KRAS dependency microRNA signature reveals a p62/Sqstm1-centered autophagy network regulated by mir-124

ANITA K. MEHTA, Kevin Hua, William Whipple, Minh-Thuy Nguyen, Stephanie Bartley, Margaret McGuiness, Jeff Settleman, Joanne Weidhaas, Anurag Singh
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): LB-C02.
https://doi.org/10.1158/1535-7163.TARG-15-LB-C02
Published: 01 December 2015
View article titled, Abstract LB-C02: A KRAS dependency microRNA signature reveals a p62/Sqstm1-centered autophagy network regulated by mir-124
Journal Articles

Abstract C155: Inhibition of TAK1 promotes apoptosis in KRAS and Wnt pathway codependent colon cancers.

Anurag Singh, Michael F. Sweeney, Jeff Settleman, Daniel A. Haber
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): C155.
https://doi.org/10.1158/1535-7163.TARG-11-C155
Published: 12 November 2011
View article titled, Abstract C155: Inhibition of TAK1 promotes apoptosis in KRAS and Wnt pathway codependent colon cancers.