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Jean-Marc Barret
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Journal Articles

Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3

Christophe Le Clorennec, Hervé Bazin, Olivier Dubreuil, Christel Larbouret, Charline Ogier, Yassamine Lazrek, Véronique Garambois, Marie-Alix Poul, Philippe Mondon, Jean-Marc Barret, Gérard Mathis, Jean-François Prost, André Pèlegrin, Thierry Chardès
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (7): 1312–1323.
https://doi.org/10.1158/1535-7163.MCT-16-0886
Published: 04 July 2017
View article titled, Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3
Open the PDF for Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3 in another window
Includes: Supplementary data
Journal Articles

Abstract A87: Synthesis and structure‐activity relationships of a series of epipodophyllotoxin polyamine conjugated derivatives vectorized for active polyamine transporter system in tumor cells, leading to the selection of F14512 for clinical trials

Thierry Imbert, Yves Guminski, Sandrine Cugnasse, Martial Grousseaud, Jean‐Marc Barret, Anna Kruczynski, Stéphane Vispe, Stéphane Gras, Jean‐Philippe Annereau, Isabelle Vandenberghe, Aline Stennevin, Laurence Lacastaignaratte, Natacha Novosad, Sandrine Pourtau, Sabine Roy, Caroline Castano, Jean‐Christophe Blanchet, Nicolas Guilbaud, Christian Bailly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): A87.
https://doi.org/10.1158/1535-7163.TARG-09-A87
Published: 10 December 2009
View article titled, Abstract A87: Synthesis and structure‐activity relationships of a series of epipodophyllotoxin polyamine conjugated derivatives vectorized for active polyamine transporter system in tumor cells, leading to the selection of F14512 for clinical trials
Journal Articles

Abstract CN08-03: Targeting topoisomerase II inhibitors to cancer cells via the polyamines transport system

Christian Bailly, Anna Kruczynski, Jean‐Marc Barret, Yves Guminski, Thierry Imbert, Nicolas Guilbaud
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): CN08-03.
https://doi.org/10.1158/1535-7163.TARG-09-CN08-03
Published: 10 December 2009
View article titled, Abstract CN08-03: Targeting topoisomerase II inhibitors to cancer cells via the polyamines transport system
Journal Articles

Triptolide is an inhibitor of RNA polymerase I and II–dependent transcription leading predominantly to down-regulation of short-lived mRNA

Stéphane Vispé, Luc DeVries, Laurent Créancier, Jérome Besse, Sophie Bréand, David J. Hobson, Jesper Q. Svejstrup, Jean-Philippe Annereau, Didier Cussac, Charles Dumontet, Nicolas Guilbaud, Jean-Marc Barret, Christian Bailly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (10): 2780–2790.
https://doi.org/10.1158/1535-7163.MCT-09-0549
Published: 12 October 2009
View article titled, Triptolide is an inhibitor of RNA polymerase I and II–dependent transcription leading predominantly to down-regulation of short-lived mRNA
Open the PDF for Triptolide is an inhibitor of RNA polymerase I and II–dependent transcription leading predominantly to down-regulation of short-lived mRNA in another window
Includes: Supplementary data
Journal Articles

F14512, a novel targeted cytotoxic agent with a potent and selective antiproliferative activity against cancer cells expressing a high level of polyamine transport system

Jean-Philippe Annereau, Jean-Marc Barret, Viviane Brel, Aline Stennevin, Karine Andre, Marie-Laure Marionneau, Vanessa Offrete, Anna Kruczynski, Yves Guminski, Thierry Imbert, Nicolas Guilbaud, Christian Bailly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A274.
Published: 01 November 2007
View article titled, F14512, a novel targeted cytotoxic agent with a potent and selective antiproliferative activity against cancer cells expressing a high level of polyamine transport system
Journal Articles

F14512, a novel targeted cytotoxic agent vectored into cells via the polyamine transport system

Jean-Marc Barret, Jean-Guy Delcros, Stephane Vispe, Jean-Philippe Annereau, Viviane Brel, Karine Andre, Aline Stennevin, Yves Guminski, Thierry Imbert, Nicolas Guilbaud, Christian Bailly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A270.
Published: 01 November 2007
View article titled, F14512, a novel targeted cytotoxic agent vectored into cells via the polyamine transport system
Journal Articles

Tumor cell-selective DNA damaging activity of the targeted cytotoxic agent F14512

Stephane Vispe, Jean-Marc Barret, Stephane Gras, Amelie Lansiaux, Brigitte Baldeyrou, Jerome Filiol, Natacha Novosad, Vanessa Offrete, Yoann Menon, Yves Guminski, Thierry Imbert, Nicolas Guilbaud, Christian Bailly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A273.
Published: 01 November 2007
View article titled, Tumor cell-selective DNA damaging activity of the targeted cytotoxic agent F14512
Journal Articles

Preclinical antitumor activity of F14512, a novel targeted cytotoxic agent

Anna Kruczynski, Isabelle Vandenberghe, Vanessa Tillement, Christel Ricome, Sandrine Pourtau, Valerie Faure, Sabine Roy, Jean-Christophe Blanchet, Caroline Castano, Nathalie Chansard, Jean-Marc Barret, Jean-Philippe Annereau, Yves Guminski, Thierry Imbert, Nicolas Guilbaud, Christian Bailly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A276.
Published: 01 November 2007
View article titled, Preclinical antitumor activity of F14512, a novel targeted cytotoxic agent